R
Roland S. Liblau
Researcher at Centre national de la recherche scientifique
Publications - 6
Citations - 664
Roland S. Liblau is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: T cell & Cytotoxic T cell. The author has an hindex of 6, co-authored 6 publications receiving 485 citations. Previous affiliations of Roland S. Liblau include Pierre-and-Marie-Curie University.
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Journal ArticleDOI
Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment.
Claudio L. Bassetti,Antoine Roger Adamantidis,Denis Burdakov,Denis Burdakov,Denis Burdakov,Fang Han,Ulf Kallweit,Ramin Khatami,Frits Koning,Brigitte R. Kornum,Gert Jan Lammers,Roland S. Liblau,Pierre H. Luppi,Pierre H. Luppi,Geert Mayer,T. Pollmacher,Takeshi Sakurai,Federica Sallusto,Federica Sallusto,Thomas E. Scammell,Mehdi Tafti,Yves Dauvilliers,Yves Dauvilliers +22 more
TL;DR: Current understanding of how genetic, environmental and immune-related factors contribute to a prominent orexin signalling deficiency in patients with NT1 are focused on, along with uncertainties concerning the ‘narcoleptic borderland’, including narcolepsy type 2 (NT2).
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Antigen-dependent and -independent Ca2+ Responses Triggered in T Cells by Dendritic Cells Compared with B Cells
TL;DR: The results suggest that Ag is better recognized by T cells on DCs essentially because T–DC adhesion precedes Ag recognition, whereas T–B adhesion requires Ag recognition.
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Myelin/oligodendrocyte glycoprotein–deficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice
Cécile Delarasse,Philippe Daubas,Lennart T. Mars,Csaba Vizler,Tobias Litzenburger,Antonio Iglesias,Jan Bauer,Bruno Della Gaspera,Anna Schubart,Laurence Decker,Dalia Dimitri,G. Roussel,Andrée Dierich,Sandra Amor,A. Dautigny,Roland S. Liblau,Danielle Pham-Dinh +16 more
TL;DR: A total lack of immune tolerance to MOG in WT C57BL/6 mice may be responsible for the high pathogenicity of the anti-MOG immune response as well as the high susceptibility of most animal strains to Mog-induced EAE.
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Role of autoreactive CD8+ T cells in organ-specific autoimmune diseases: insight from transgenic mouse models.
TL;DR: The study of autoreactive CD8+ T cells and the characterization of their antigenic specificity should help unravel the pathophysiology of organ‐specific autoimmune diseases, help identify exacerbating foreign antigens, and allow the design of antigen‐specific immunotherapy targeting the pathogenic autore active T cells.
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Bispecificity for Myelin and Neuronal Self-Antigens Is a Common Feature of CD4 T Cells in C57BL/6 Mice
Liliana E. Lucca,Sabine Desbois,Abdulraouf Ramadan,Avraham Ben-Nun,Miriam Eisenstein,Nadège Carrié,Jean-Charles Guéry,Alessandro Sette,Phuong Nguyen,Terrence L. Geiger,Lennart T. Mars,Roland S. Liblau +11 more
TL;DR: Data indicate that due to linear sequence homology, part of the MOG35–55-specific T cell repertoire of all C57BL/6 mice also recognizes NF-M15–35, with potential implications for CNS autoimmunity.