R
Ronald M. Evans
Researcher at Salk Institute for Biological Studies
Publications - 729
Citations - 176865
Ronald M. Evans is an academic researcher from Salk Institute for Biological Studies. The author has contributed to research in topics: Nuclear receptor & Receptor. The author has an hindex of 199, co-authored 708 publications receiving 166722 citations. Previous affiliations of Ronald M. Evans include Scripps Research Institute & University of California, Davis.
Papers
More filters
Journal ArticleDOI
Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1.
Tohru Tsukui,Javier Capdevila,Koji Tamura,Pilar Ruiz-Lozano,Concepción Rodríguez-Esteban,Sayuri Yonei-Tamura,Jorge Magallon,Roshantha A.S. Chandraratna,Kenneth R. Chien,Bruce Blumberg,Bruce Blumberg,Ronald M. Evans,Juan Carlos Izpisua Belmonte +12 more
TL;DR: It is demonstrated that retinoic acid controls Lefty-1 expression in a pathway downstream or parallel to Shh, and evidence that RA controls left-right development across vertebrate species is provided.
Journal ArticleDOI
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR)
Junichiro Sonoda,Wen Xie,John M. Rosenfeld,Joyce L. Barwick,Philip S. Guzelian,Ronald M. Evans +5 more
TL;DR: It is proposed that PXR serves as a master regulator of the phase I and II responses to facilitate rapid and efficient detoxification and elimination of foreign chemicals.
Journal ArticleDOI
Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor α clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia
Wilson H. Miller,Akira Kakizuka,Stanley R. Frankel,Raymond P. Warrell,Anthony DeBlasio,Kristi Levine,Ronald M. Evans,Ronald M. Evans,Ethan Dmitrovsky +8 more
TL;DR: RT-PCR for PML/RAR-alpha mRNA provides a more-sensitive test for the t(15;17) than routine cytogenetics or Northern analysis, and best defines this RA-responsive malignancy.
Journal ArticleDOI
The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export
TL;DR: Binding of Spt6 to Ser2-P RNAPII provides a cotranscriptional mechanism to recruit Iws1, REF1/Aly, and associated mRNA processing, surveillance, and export factors to responsive genes.
Journal ArticleDOI
Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.
TL;DR: A novel in vivo nucleic acid labeling approach is demonstrated to demonstrate the existence of nascent RNA polymerase II transcripts within this nuclear body, and to show that PML and the transactivation cofactor, CREB binding protein (CBP), colocalize within the nucleus.