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Sai Kiang Lim

Researcher at Agency for Science, Technology and Research

Publications -  167
Citations -  24991

Sai Kiang Lim is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Mesenchymal stem cell & Microvesicles. The author has an hindex of 52, co-authored 152 publications receiving 18269 citations. Previous affiliations of Sai Kiang Lim include Genome Institute of Singapore & National University of Singapore.

Papers
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Journal ArticleDOI

Delineating biological pathways unique to embryonic stem cell-derived insulin-producing cell lines from their noninsulin-producing progenitor cell lines.

TL;DR: Gene expression analysis has identified the PPP, clathrin-mediated endocytosis, and the PPAR signaling pathway as the major delineating pathways in these insulin-producing cell lines, and their biological relevance was confirmed by biochemical and cellular assays.
Patent

Pre-eclampsia biomarkers

TL;DR: In this article, the authors describe a method of detecting pre-eclampsia in a cell, tissue, organ or organism, the method comprising detecting a modulated level of expression, activity, or amount of a biomarker polypeptide selected from the group consisting of PlGF, FLT1, BNP, ANP, CD9, PAI-1, TGF β, PCT, SI 00b, TIMP1, CD 105 and IL6 in or of a microparticle type.
Journal ArticleDOI

HuMSC-EV induce monocyte/macrophage mobilization to orchestrate neovascularization in wound healing process following radiation injury

TL;DR: HuMSC-derived extracellular vesicles were locally administered in mice hindlimb following 80-Gy X-ray irradiation and animals were monitored at different time points as mentioned in this paper .
Book ChapterDOI

Embryonic Stem Cells for Therapies – Challenges and Possibilities

TL;DR: The successful establishment of human embryonic stem cells in culture has raised unprecedented public interest and expectation of treating intractable diseases such as diabetes, spinal cord injuries, neurodegenerative and cardiovascular diseases, but translation of hESC into therapies has been challenging.
Journal ArticleDOI

Multivariate statistical methods in the forensic investigation of the post-blast residues measured by Fourier transform infrared spectroscopy

TL;DR: In this article, Fourier transform infrared (FTIR) spectroscopy has gained significant attention among the forensic scientists because it shows high sensitivity and selectivity, and offers near-real-time detection.