S
Sai Kiang Lim
Researcher at Agency for Science, Technology and Research
Publications - 167
Citations - 24991
Sai Kiang Lim is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Mesenchymal stem cell & Microvesicles. The author has an hindex of 52, co-authored 152 publications receiving 18269 citations. Previous affiliations of Sai Kiang Lim include Genome Institute of Singapore & National University of Singapore.
Papers
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Journal ArticleDOI
Delineating biological pathways unique to embryonic stem cell-derived insulin-producing cell lines from their noninsulin-producing progenitor cell lines.
Tiansheng Chen,Soon Sim Tan,Ronne Wee Yeh Yeo,Bao Ju Teh,Ruihua Luo,Guodong Li,Sai Kiang Lim,Sai Kiang Lim +7 more
TL;DR: Gene expression analysis has identified the PPP, clathrin-mediated endocytosis, and the PPAR signaling pathway as the major delineating pathways in these insulin-producing cell lines, and their biological relevance was confirmed by biochemical and cellular assays.
Patent
Pre-eclampsia biomarkers
Sai Kiang Lim,Kok Hian Tan +1 more
TL;DR: In this article, the authors describe a method of detecting pre-eclampsia in a cell, tissue, organ or organism, the method comprising detecting a modulated level of expression, activity, or amount of a biomarker polypeptide selected from the group consisting of PlGF, FLT1, BNP, ANP, CD9, PAI-1, TGF β, PCT, SI 00b, TIMP1, CD 105 and IL6 in or of a microparticle type.
Journal ArticleDOI
HuMSC-EV induce monocyte/macrophage mobilization to orchestrate neovascularization in wound healing process following radiation injury
Céline Loinard,A Ribault,Bruno Lhomme,Marc Benderitter,Stephane Flamant,Sandrine Paul,Valérie Dubois,Ruenn Chai Lai,Sai Kiang Lim,Radia Tamarat +9 more
TL;DR: HuMSC-derived extracellular vesicles were locally administered in mice hindlimb following 80-Gy X-ray irradiation and animals were monitored at different time points as mentioned in this paper .
Book ChapterDOI
Embryonic Stem Cells for Therapies – Challenges and Possibilities
Ronne Wee Yeh Yeo,Sai Kiang Lim +1 more
TL;DR: The successful establishment of human embryonic stem cells in culture has raised unprecedented public interest and expectation of treating intractable diseases such as diabetes, spinal cord injuries, neurodegenerative and cardiovascular diseases, but translation of hESC into therapies has been challenging.
Journal ArticleDOI
Multivariate statistical methods in the forensic investigation of the post-blast residues measured by Fourier transform infrared spectroscopy
Krzysztof Banas,Agnieszka Banas,Herbert O. Moser,M. Bahou,Marian Cholewa,Ping Yang,Sai Kiang Lim +6 more
TL;DR: In this article, Fourier transform infrared (FTIR) spectroscopy has gained significant attention among the forensic scientists because it shows high sensitivity and selectivity, and offers near-real-time detection.