S
Sai Kiang Lim
Researcher at Agency for Science, Technology and Research
Publications - 167
Citations - 24991
Sai Kiang Lim is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Mesenchymal stem cell & Microvesicles. The author has an hindex of 52, co-authored 152 publications receiving 18269 citations. Previous affiliations of Sai Kiang Lim include Genome Institute of Singapore & National University of Singapore.
Papers
More filters
Journal ArticleDOI
Hypoxia Modulates A431 Cellular Pathways Association to Tumor Radioresistance and Enhanced Migration Revealed by Comprehensive Proteomic and Functional Studies
Yan Ren,Piliang Hao,Bamaprasad Dutta,Esther Sok Hwee Cheow,Kae Hwan Sim,Chee Sian Gan,Sai Kiang Lim,Siu Kwan Sze +7 more
TL;DR: The results revealed that hypoxia induced several biological processes involved in tumor migration and radioresistance and provided potential new targets for tumor therapy.
Journal ArticleDOI
Role of haptoglobin in free hemoglobin metabolism.
TL;DR: The strong avidity with which Hp binds hemoglobin and the high conservation of the Hp gene across species suggest that Hp plays an important role in the metabolism of free hemoglobin.
Journal ArticleDOI
Phenotyping of an in vitro model of ischemic penumbra by iTRAQ-based shotgun quantitative proteomics.
Arnab Datta,Jung Eun Park,Xin Li,Huoming Zhang,Zhi Shan Ho,Klaus Heese,Sai Kiang Lim,James P. Tam,Siu Kwan Sze +8 more
TL;DR: This study shows the potential application of iTRAQ-based quantitative proteomics for the elucidation of pathophysiology and the discovery of novel therapeutic targets in the field of neuroproteomics.
Book ChapterDOI
Mesenchymal Stem Cell Exosomes: The Future MSC-Based Therapy?
Ruenn Chai Lai,Ronne Wee Yeh Yeo,Ronne Wee Yeh Yeo,Soon Sim Tan,Bin Zhang,Yijun Yin,Newman Siu Kwan Sze,Andre Choo,Sai Kiang Lim +8 more
TL;DR: The exosome, a secreted membrane vesicle, is identified, as an active therapeutic factor in MSC secretion, and could potentially underpin the therapeutic efficacy of MSC in diverse disease indications.
Journal ArticleDOI
Plasma biomarker discovery in preeclampsia using a novel differential isolation technology for circulating extracellular vesicles.
Kok Hian Tan,Kok Hian Tan,Soon Sim Tan,Siu Kwan Sze,Wai Kheong Ryan Lee,Mor Jack Ng,Sai Kiang Lim +6 more
TL;DR: Cholera toxin B chain (CTB) and annexin V (AV) which respectively bind GM1 ganglioside and phosphatidylserine were used to isolate extracellular vesicles from plasma of PE patients and healthy pregnant women.