S
Sai Kiang Lim
Researcher at Agency for Science, Technology and Research
Publications - 167
Citations - 24991
Sai Kiang Lim is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Mesenchymal stem cell & Microvesicles. The author has an hindex of 52, co-authored 152 publications receiving 18269 citations. Previous affiliations of Sai Kiang Lim include Genome Institute of Singapore & National University of Singapore.
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Journal ArticleDOI
A preliminary investigation of circulating extracellular vesicles and biomarker discovery associated with treatment response in head and neck squamous cell carcinoma
Dorival Mendes Rodrigues-Junior,Soon Sim Tan,Luciano de Souza Viana,André Lopes Carvalho,Sai Kiang Lim,N. Gopalakrishna Iyer,André Luiz Vettore +6 more
TL;DR: Gene Set Enrichment Analysis and Search Tool for the Retrieval of Interacting Genes database analysis indicated that the content of circulating plasma EVs might have a relevant function for the tumor intercellular communication in the HNSCC patients.
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Embryonic Cell Lines with Endothelial Potential: An In Vitro System for Studying Endothelial Differentiation
TL;DR: Embryonic cell lines that differentiate exclusively into endothelial cells were derived from early mouse embryos using empirical but reproducible culture techniques without viral or chemical transformation and can undergo in vitro and in vivo endothelial differentiation that recapitulated known endothelium differentiation pathways.
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Consequences of haemolysis without haptoglobin.
TL;DR: The data suggest that Hp plays a pivotal role in reducing renal oxidative damage during haemolysis, and gross pathological analysis indicated that the kidney was the most affected tissue in phenylhydrazine-treated Hp-/- and Hp+/+ mice, and H p-/- mice were more severely affected.
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Generating mESC-derived insulin-producing cell lines through an intermediate lineage-restricted progenitor line
Guodong Li,Ruihua Luo,Jiping Zhang,Keng Suan Yeo,Qizhou Lian,Fei Xie,Eileen Khia Way Tan,Dorothée Caille,Oi Lian Kon,Manuel Salto-Tellez,Paolo Meda,Sai Kiang Lim,Sai Kiang Lim,Sai Kiang Lim +13 more
TL;DR: A novel reproducible protocol to establish homogeneous and scalable insulin-producing cell lines from mouse (m) ESCs via differentiation of the previously described lineage-restricted clonal mESC-derived E-RoSH cells is described.
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Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes
Jia Tong Loh,Bin Zhang,Joey Kay Hui Teo,Ruenn Chai Lai,Andre Choo,Kong-Peng Lam,Sai Kiang Lim +6 more
TL;DR: In this article , the authors identified a feed-forward loop between complements and neutrophils that could amplify and perpetuate the cytokine storm seen in severe SARS-CoV-2-infected patients.