Sandeep Dhayade

TL;DR: In this paper, the nuclear-cytosolic acetyl-CoA synthetase 2 (ACSS2) was found to sustain the growth of hypoxic tumor cells.

TL;DR: In this article, the authors investigated MCL-1 protein expression in a breast cancer tissue microarray and correlate this with clinical data, finding that high MCL1 expression is associated with poor outcome in breast cancer.

TL;DR: The role of cGMP in the vascular responses to NaHS is confirmed and genetic deletion of PKG-I attenuates NaHS and L-cysteine-stimulated vasodilation and suggests that there is a cross-talk between KATP and PKG.

TL;DR: It is shown that formate production in murine cancers with high oxidative metabolism exceeds the biosynthetic demand and that high formate levels promotes invasion of cancer cells, a hallmark of oxidative cancers.

TL;DR: It is identified that C-type natriuretic peptide (CNP), a ligand of the membrane-bound guanylate cyclase B, enhances the activity of cGMP-dependent protein kinase I (cGKI) in melanoma cells by increasing the intracellular levels of c GMP.