S
Sandra K. Erickson
Researcher at University of California, San Francisco
Publications - 77
Citations - 5570
Sandra K. Erickson is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Cholesterol & Reverse cholesterol transport. The author has an hindex of 36, co-authored 77 publications receiving 5332 citations. Previous affiliations of Sandra K. Erickson include Veterans Health Administration & Stanford University.
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Journal ArticleDOI
Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis
Sylvaine Cases,Steven J. Smith,Yaowu Zheng,Heather M. Myers,Steven R. Lear,Eric Sande,Sabine Novak,Colin Collins,Carrie B. Welch,Aldons J. Lusis,Sandra K. Erickson,Robert V. Farese +11 more
TL;DR: An expressed sequence tag clone that shared regions of similarity with acyl CoA:cholesterol acyltransferase, an enzyme that also uses fatty acyl coA as a substrate was identified, which will greatly facilitate studies of cellular glycerolipid metabolism and its regulation.
Journal ArticleDOI
Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype
Clive R. Pullinger,Celeste Eng,Gerald Salen,Sarah Shefer,Ashok K. Batta,Sandra K. Erickson,Andrea Verhagen,Christopher R. Rivera,Sean J. Mulvihill,Mary J. Malloy,John P. Kane +10 more
TL;DR: A new metabolic disorder presenting with hyperlipidemia caused by a homozygous deletion mutation in CYP7A1 is reported, which leads to a frameshift that results in loss of the active site and enzyme function.
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ACAT-2, A Second Mammalian Acyl-CoA:Cholesterol Acyltransferase ITS CLONING, EXPRESSION, AND CHARACTERIZATION
Sylvaine Cases,Sabine Novak,Yaowu Zheng,Heather M. Myers,Steven R. Lear,Steven R. Lear,Eric Sande,Carrie B. Welch,Aldons J. Lusis,Thomas A. Spencer,Brian R. Krause,Sandra K. Erickson,Sandra K. Erickson,Robert V. Farese +13 more
TL;DR: A second mammalian ACAT enzyme is described, designated ACAT-2, that is 44% identical to the first cloned mouse ACAT (henceforth designated ACat-1) and will facilitate molecular approaches to understanding the role of ACAT enzymes in mammalian biology.
Journal ArticleDOI
CEACAM1 regulates insulin clearance in liver
Matthew N. Poy,Yan Yang,Khadijeh Rezaei,Mats A. Fernström,Abraham D. Lee,Yoshiaki Kido,Sandra K. Erickson,Sonia M. Najjar +7 more
TL;DR: A mechanism through which insulin signaling regulates insulin sensitivity by modulating hepatic insulin clearance is suggested by suggesting that CEACAM1 phosphorylation leads to upregulation of receptor-mediated insulin endocytosis and degradation in the hepatocyte.
Journal ArticleDOI
The dual role of mevalonate in the cell cycle.
V Quesney-Huneeus,H A Galick,Marvin D. Siperstein,Sandra K. Erickson,Thomas A. Spencer,J A Nelson +5 more
TL;DR: It was shown that the cholesterol requirement is limited to the early and mid-G1 phases, whereas the isopentenyl effect is required at the late G1-S interphase of the cell cycle.