S
Sebastian Maier
Publications - 5
Citations - 1122
Sebastian Maier is an academic researcher. The author has contributed to research in topics: Lung cancer & Homeobox A1. The author has an hindex of 4, co-authored 5 publications receiving 1051 citations.
Papers
More filters
Journal ArticleDOI
Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer
Jonathan Weiss,Martin L. Sos,Danila Seidel,Martin Peifer,Thomas Zander,Johannes M. Heuckmann,Roland T. Ullrich,Roopika Menon,Sebastian Maier,Alex Soltermann,Holger Moch,Patrick Wagener,Florian Fischer,Stefanie Heynck,Mirjam Koker,Jakob Schöttle,Frauke Leenders,Franziska Gabler,Ines Dabow,Silvia Querings,Lukas C. Heukamp,Hyatt Balke-Want,Sascha Ansén,Daniel Rauh,Ingelore Baessmann,Janine Altmüller,Zoe Wainer,Matthew Conron,Gavin M. Wright,Prudence A. Russell,Ben Solomon,Elisabeth Brambilla,Christian Brambilla,Philippe Lorimier,Steinar Sollberg,Odd Terje Brustugun,Walburga Engel-Riedel,Corinna Ludwig,Iver Petersen,Jörg Sänger,Joachim H. Clement,Harry J.M. Groen,Wim Timens,Hannie Sietsma,Erik Thunnissen,Egbert F. Smit,Daniëlle A.M. Heideman,Federico Cappuzzo,C. Ligorio,Stefania Damiani,Michael Hallek,Rameen Beroukhim,William Pao,Bert Klebl,Matthias Baumann,Reinhard Buettner,Karen Ernestus,Erich Stoelben,Jürgen Wolf,Peter Nürnberg,Peter Nürnberg,Sven Perner,Roman K. Thomas +62 more
TL;DR: F focal FGFR1 amplification is common in squamous cell lung cancer and associated with tumor growth and survival, suggesting that FGFR inhibitors may be a viable therapeutic option in this cohort of patients.
Journal ArticleDOI
SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer
Theresia Wilbertz,Patrick L. Wagner,Karen Petersen,Ann-Cathrin Stiedl,Veit Scheble,Sebastian Maier,Markus Reischl,Ralf Mikut,Nasser K. Altorki,Holger Moch,Falko Fend,Annette Staebler,Adam J. Bass,Adam J. Bass,Matthew Meyerson,Mark A. Rubin,Alex Soltermann,Claudia Lengerke,Sven Perner +18 more
TL;DR: High SOX2 expression levels proved to be a marker for prolonged overall survival among patients with squamous cell carcinomas and adenocarcinomas of the lung and are associated with indicators of favorable prognosis.
Journal ArticleDOI
SOX2 amplification is a common event in squamous cell carcinomas of different organ sites
Sebastian Maier,Theresia Wilbertz,Martin Braun,Veit Scheble,Markus Reischl,Ralf Mikut,Roopika Menon,Pavel Nikolov,Karen Petersen,Christine Beschorner,Holger Moch,Christoph Kakies,Chris Protzel,Jürgen Bauer,Alex Soltermann,Falko Fend,Annette Staebler,Claudia Lengerke,Sven Perner +18 more
TL;DR: It is concluded that SOX2 amplification and consequentSOX2 protein overexpression may represent important mechanisms of tumor initiation and progression in a considerable subset of squamous cell carcinomas.
Journal ArticleDOI
Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer (Science Translational Medicine (2012) 4, (130er2))
Jonathan Weiss,Martin L. Sos,Danila Seidel,Martin Peifer,Thomas Zander,Johannes M. Heuckmann,Roland T. Ullrich,Roopika Menon,Sebastian Maier,Alex Soltermann,Holger Moch,P. Wagener,Florian Fischer,Stefanie Heynck,Mirjam Koker,Jakob Schöttle,Frauke Leenders,Franziska Gabler,I. Dabow,Silvia Querings,Lukas C. Heukamp,Hyatt Balke-Want,Sascha Ansén,Daniel Rauh,Ingelore Baessmann,Janine Altmüller,Zoe Wainer,Matthew Conron,Gavin M. Wright,Prudence A. Russell,Ben Solomon,Elizabeth Brambilla,Christian Brambilla,Philippe Lorimier,S. Sollberg,Odd Terje Brustugun,Walburga Engel-Riedel,Corinna Ludwig,Iver Petersen,Jörg Sänger,Joachim H. Clement,Hendricus Groen,Wim Timens,Hannie Sietsma,Erik Thunnissen,E.F. Smit,Daniëlle A M Heideman,Federico Cappuzzo,C. Ligorio,Stefania Damiani,Michael Hallek,Rameen Beroukhim,William Pao,Bert Klebl,M. Baumann,Reinhard Buettner,Karen Ernestus,Erich Stoelben,Juergen Wolf,Peter Nürnberg,Sven Perner,Roman K. Thomas +61 more
Journal ArticleDOI
NKX2-1 (NK2 homeobox 1)
TL;DR: Review on NKX2-1 (NK2 homeobox 1), with data on DNA, on the protein encoded, and where the gene is implicated.