D
Daniëlle A M Heideman
Researcher at VU University Amsterdam
Publications - 59
Citations - 3246
Daniëlle A M Heideman is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Cervical intraepithelial neoplasia & Cervical cancer. The author has an hindex of 20, co-authored 59 publications receiving 2541 citations. Previous affiliations of Daniëlle A M Heideman include University of Washington.
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Journal ArticleDOI
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
Martin Peifer,Lynnette Fernandez-Cuesta,Martin L. Sos,Julie George,Danila Seidel,Lawryn H. Kasper,Dennis Plenker,Frauke Leenders,Ruping Sun,Thomas Zander,Roopika Menon,Mirjam Koker,Ilona Dahmen,Christian Müller,Vincenzo Di Cerbo,Hans Ulrich Schildhaus,Janine Altmüller,Ingelore Baessmann,Christian Becker,Bram De Wilde,Jo Vandesompele,Diana Böhm,Sascha Ansén,Franziska Gabler,Ines Wilkening,Stefanie Heynck,Johannes M. Heuckmann,Xin Lu,Scott L. Carter,Kristian Cibulskis,Shantanu Banerji,Gad Getz,Kwon-Sik Park,Daniel Rauh,Christian Grütter,Matthias Fischer,Laura Pasqualucci,Gavin M. Wright,Zoe Wainer,Prudence A. Russell,Iver Petersen,Yuan Chen,Erich Stoelben,Corinna Ludwig,Philipp A. Schnabel,Hans Hoffmann,Thomas Muley,Michael Brockmann,Walburga Engel-Riedel,Lucia Anna Muscarella,Vito Michele Fazio,Harry J.M. Groen,Wim Timens,Hannie Sietsma,Erik Thunnissen,Egber Smit,Daniëlle A M Heideman,Peter J.F. Snijders,Federico Cappuzzo,C. Ligorio,Stefania Damiani,John K. Field,Steinar Solberg,Odd Terje Brustugun,Marius Lund-Iversen,Jörg Sänger,Joachim H. Clement,Alex Soltermann,Holger Moch,Walter Weder,Benjamin Solomon,Jean-Charles Soria,Pierre Validire,Benjamin Besse,Elisabeth Brambilla,Christian Brambilla,Sylvie Lantuejoul,Philippe Lorimier,Peter M. Schneider,Michael Hallek,William Pao,Matthew Meyerson,Matthew Meyerson,Julien Sage,Jay Shendure,Robert Schneider,Robert Schneider,Reinhard Büttner,Jürgen Wolf,Peter Nürnberg,Sven Perner,Lukas C. Heukamp,Paul K. Brindle,Stefan A. Haas,Roman K. Thomas +94 more
TL;DR: This study implicates histone modification as a major feature of SCLC, reveals potentially therapeutically tractable genomic alterations and provides a generalizable framework for the identification of biologically relevant genes in the context of high mutational background.
Journal ArticleDOI
Human papillomavirus testing for the detection of high-grade cervical intraepithelial neoplasia and cancer: final results of the POBASCAM randomised controlled trial
D.C. Rijkaart,Johannes Berkhof,Lawrence Rozendaal,Folkert J. van Kemenade,N. W. J. Bulkmans,Daniëlle A M Heideman,Gemma G. Kenter,Jack Cuzick,Peter J.F. Snijders,Chris J.L.M. Meijer +9 more
TL;DR: The aim of this study was to assess whether HPV DNA testing in the first screen decreases detection of cervical intraepithelial neoplasia (CIN) grade 3 or worse, CIN grade 2 or better, and cervical cancer in the second screening.
Journal ArticleDOI
Triage by methylation-marker testing versus cytology in women who test HPV-positive on self-collected cervicovaginal specimens (PROHTECT-3): a randomised controlled non-inferiority trial
Viola M.J. Verhoef,Remko P. Bosgraaf,Folkert J. van Kemenade,Folkert J. van Kemenade,Lawrence Rozendaal,Daniëlle A M Heideman,Albertus T. Hesselink,Ruud L.M. Bekkers,Renske D.M. Steenbergen,Leon F.A.G. Massuger,Willem J. G. Melchers,Johan Bulten,Lucy I H Overbeek,Johannes Berkhof,Peter J.F. Snijders,Chris J.L.M. Meijer +15 more
TL;DR: DNA methylation analysis of MAL and miR-124-2 genes on HPV-test-positive self-samples is non-inferior to cytology triage in the detection of CIN2 or worse, opening the way to full molecular screening.
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Performance of human papillomavirus testing on self-collected versus clinician-collected samples for the detection of cervical intraepithelial neoplasia of grade 2 or worse: a randomised, paired screen-positive, non-inferiority trial
Nicole J Polman,Renée M.F. Ebisch,Daniëlle A M Heideman,Willem J. G. Melchers,Ruud L.M. Bekkers,Anco Molijn,Chris J.L.M. Meijer,Wim Quint,Peter J.F. Snijders,Leon F.A.G. Massuger,Folkert J. van Kemenade,Johannes Berkhof +11 more
TL;DR: It is suggested that HPV self-sampling could be used as a primary screening method in routine screening by evaluating the clinical accuracy of primary HPV testing on self-collected samples within an organised screening setting.
Journal ArticleDOI
CADM1 and MAL promoter methylation levels in hrHPV‐positive cervical scrapes increase proportional to degree and duration of underlying cervical disease
Mariska Bierkens,Albertus T. Hesselink,Chris J.L.M. Meijer,Daniëlle A M Heideman,G. Bea A. Wisman,Ate G.J. van der Zee,Peter J.F. Snijders,Renske D.M. Steenbergen +7 more
TL;DR: CADM1 and MAL promoter methylation levels in hrHPV‐positive cervical scrapes are related to the degree and duration of underlying cervical disease and markedly increased in cervical cancer.