Deep learning is a form of machine learning that enables computers to learn from experience and understand the world in terms of a hierarchy of concepts. Because the computer gathers knowledge from experience, there is no need for a human computer operator to formally specify all the knowledge that the computer needs. The hierarchy of concepts allows the computer to learn complicated concepts by building them out of simpler ones; a graph of these hierarchies would be many layers deep. This book introduces a broad range of topics in deep learning. The text offers mathematical and conceptual background, covering relevant concepts in linear algebra, probability theory and information theory, numerical computation, and machine learning. It describes deep learning techniques used by practitioners in industry, including deep feedforward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology; and it surveys such applications as natural language processing, speech recognition, computer vision, online recommendation systems, bioinformatics, and videogames. Finally, the book offers research perspectives, covering such theoretical topics as linear factor models, autoencoders, representation learning, structured probabilistic models, Monte Carlo methods, the partition function, approximate inference, and deep generative models. Deep Learning can be used by undergraduate or graduate students planning careers in either industry or research, and by software engineers who want to begin using deep learning in their products or platforms. A website offers supplementary material for both readers and instructors.

Deep Learning

We describe latent Dirichlet allocation (LDA), a generative probabilistic model for collections of discrete data such as text corpora. LDA is a three-level hierarchical Bayesian model, in which each item of a collection is modeled as a finite mixture over an underlying set of topics. Each topic is, in turn, modeled as an infinite mixture over an underlying set of topic probabilities. In the context of text modeling, the topic probabilities provide an explicit representation of a document. We present efficient approximate inference techniques based on variational methods and an EM algorithm for empirical Bayes parameter estimation. We report results in document modeling, text classification, and collaborative filtering, comparing to a mixture of unigrams model and the probabilistic LSI model.

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Latent dirichlet allocation

We propose a generative model for text and other collections of discrete data that generalizes or improves on several previous models including naive Bayes/unigram, mixture of unigrams [6], and Hof-mann's aspect model, also known as probabilistic latent semantic indexing (pLSI) [3]. In the context of text modeling, our model posits that each document is generated as a mixture of topics, where the continuous-valued mixture proportions are distributed as a latent Dirichlet random variable. Inference and learning are carried out efficiently via variational algorithms. We present empirical results on applications of this model to problems in text modeling, collaborative filtering, and text classification.

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Latent Dirichlet Allocation

Data Mining: Practical Machine Learning Tools and Techniques offers a thorough grounding in machine learning concepts as well as practical advice on applying machine learning tools and techniques in real-world data mining situations. This highly anticipated third edition of the most acclaimed work on data mining and machine learning will teach you everything you need to know about preparing inputs, interpreting outputs, evaluating results, and the algorithmic methods at the heart of successful data mining. Thorough updates reflect the technical changes and modernizations that have taken place in the field since the last edition, including new material on Data Transformations, Ensemble Learning, Massive Data Sets, Multi-instance Learning, plus a new version of the popular Weka machine learning software developed by the authors. Witten, Frank, and Hall include both tried-and-true techniques of today as well as methods at the leading edge of contemporary research. *Provides a thorough grounding in machine learning concepts as well as practical advice on applying the tools and techniques to your data mining projects *Offers concrete tips and techniques for performance improvement that work by transforming the input or output in machine learning methods *Includes downloadable Weka software toolkit, a collection of machine learning algorithms for data mining tasks-in an updated, interactive interface. Algorithms in toolkit cover: data pre-processing, classification, regression, clustering, association rules, visualization

Data Mining: Practical Machine Learning Tools and Techniques

抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

One of the ultimate goals of the field of artificial intelligence and robotics is to develop systems that assist us in our everyday lives by autonomously carrying out a variety of different tasks To achieve this and to generate appropriate actions, such systems need to be able to accurately interpret their sensory input and estimate their state or the state of the environment to be successful In recent years, probabilistic approaches have emerged as a key technology for these problems In this article, we will describe state-of-the-art solutions to challenging tasks from the area of mobile robotics, autonomous cars, and activity recognition, which are all based on the paradigm of probabilistic state estimation

Probabilistic State Estimation Techniques for Autonomous and Decision Support Systems

Focusing on examples of knowledge systems and machine learning, this paper illustrates the transfer of AI technology from science to real-world applications. Decades of AI research precede a rather short but significant period, in which companies report the useful exploitation of AI technology. This paper illustrates the role played by science, and it argues that AI is just beginning to produce an ever increasingly variety of real world applications. Keyword Codes: I.2.0; I.2.1; I.2.6

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From AI Technology Research to Applications.

: We describe a heuristic search algorithm for generating optimal plans in a new class of decision problem, characterized by the incorporation of hidden state. The approach exploits the nature of the hidden state to reduce the state space by orders of magnitude. It then interleaves AO*-type heuristic expansion of the reduced space with forwards and backwards propagation phases to produce a solution in a fraction of the time required by other techniques. Results are provided on an outdoor path planning application.

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Planning with pinch points

In this paper we describe a scalable algorithm for the simultaneous mapping and localization (SLAM) problem. SLAM is the problem of acquiring a map of a static environment with a mobile robot. The vast majority of SLAM algorithms are based on the extended Kalman filter (EKF). In this paper we advocate an algorithm that relies on the dual of the EKF, the extended information filter (EIF). We show that when represented in the information form, map posteriors are dominated by a small number of links that tie together nearby features in the map. This insight is developed into a sparse variant of the EIF, called the sparse extended information filter (SEIF). SEIFs represent maps by graphical networks of features that are locally interconnected, where links represent relative information between pairs of nearby features, as well as information about the robot's pose relative to the map. We show that all essential update equations in SEIFs can be executed in constant time, irrespective of the size of the map. We also provide empirical results obtained for a benchmark data set collected in an outdoor environment, and using a multi-robot mapping simulation.

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Sebastian Thrun

Papers

Probabilistic State Estimation Techniques for Autonomous and Decision Support Systems

From AI Technology Research to Applications.

Planning with pinch points

Simultaneous and Mapping With Sparse Extended Information

Robotics Research: Results of the 12th International Symposium ISRR (Springer Tracts in Advanced Robotics)