S
Serge A.R.B. Rombouts
Researcher at Leiden University Medical Center
Publications - 238
Citations - 29190
Serge A.R.B. Rombouts is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Resting state fMRI & Functional magnetic resonance imaging. The author has an hindex of 79, co-authored 234 publications receiving 26071 citations. Previous affiliations of Serge A.R.B. Rombouts include Leiden University & Loyola University Medical Center.
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Journal ArticleDOI
Global and local gray matter loss in mild cognitive impairment and Alzheimer's disease.
G. Karas,P. Scheltens,Serge A.R.B. Rombouts,Pieter Jelle Visser,R.A. van Schijndel,Nick C. Fox,Frederik Barkhof +6 more
TL;DR: GM loss in the MTL characterizes MCI, while GM loss inThe parietal and cingulate cortices might be a feature of AD, according to patterns of gray matter loss.
Journal ArticleDOI
Loss of 'small-world' networks in Alzheimer's disease: graph analysis of FMRI resting-state functional connectivity.
Ernesto J. Sanz-Arigita,Menno M. Schoonheim,Jessica S. Damoiseaux,Serge A.R.B. Rombouts,Erik Maris,Frederik Barkhof,Philip Scheltens,Cornelis J. Stam +7 more
TL;DR: Evidence is presented of AD-induced changes in global brain functional connectivity specifically affecting long-distance connectivity, which supports the anterior-posterior disconnection theory and its role in AD.
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Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
Jonathan D. Rohrer,Jennifer M. Nicholas,Jennifer M. Nicholas,David M. Cash,John C. van Swieten,Elise G.P. Dopper,Lize C. Jiskoot,Rick van Minkelen,Serge A.R.B. Rombouts,M. Jorge Cardoso,Shona Clegg,Miklos Espak,Simon Mead,David L. Thomas,Enrico De Vita,Mario Masellis,Sandra E. Black,Morris Freedman,Ron Keren,Bradley J. MacIntosh,Ekaterina Rogaeva,David F. Tang-Wai,Maria Carmela Tartaglia,Robert Laforce,Fabrizio Tagliavini,Pietro Tiraboschi,Veronica Redaelli,Sara Prioni,Marina Grisoli,Barbara Borroni,Alessandro Padovani,Daniela Galimberti,Elio Scarpini,Andrea Arighi,Giorgio G. Fumagalli,James B. Rowe,Ian Coyle-Gilchrist,Caroline Graff,Caroline Graff,Marie Fallström,Vesna Jelic,Vesna Jelic,Anne Kinhult Ståhlbom,Anne Kinhult Ståhlbom,Christin Andersson,Christin Andersson,Håkan Thonberg,Håkan Thonberg,Lena Lilius,Giovanni B. Frisoni,Giuliano Binetti,Michela Pievani,Martina Bocchetta,Luisa Benussi,Roberta Ghidoni,Elizabeth Finger,Sandro Sorbi,Benedetta Nacmias,Gemma Lombardi,Cristina Polito,Jason D. Warren,Sebastien Ourselin,Nick C. Fox,Martin N. Rossor +63 more
TL;DR: Structural imaging and cognitive changes can be identified 5-10 years before expected onset of symptoms in asymptomatic adults at risk of genetic frontotemporal dementia, which could help to define biomarkers that can stage presymPTomatic disease and track disease progression.
Journal ArticleDOI
Adolescent risky decision-making: neurocognitive development of reward and control regions.
Linda Van Leijenhorst,Bregtje Gunther Moor,Bregtje Gunther Moor,Zdeňa A. Op de Macks,Serge A.R.B. Rombouts,Serge A.R.B. Rombouts,P. Michiel Westenberg,Eveline A. Crone +7 more
TL;DR: In this paper, the authors used fMRI to study the effect of adolescent's risky behavior on the ventral medial prefrontal cortex (VM) prefrontal cortex and ventral striatum (VS).
Journal ArticleDOI
A comprehensive study of gray matter loss in patients with Alzheimer’s disease using optimized voxel-based morphometry
G. Karas,Emma J. Burton,Serge A.R.B. Rombouts,R.A. van Schijndel,John T. O'Brien,P. Scheltens,Ian G. McKeith,David Williams,Clive Ballard,Frederik Barkhof +9 more
TL;DR: This work demonstrates global cortical atrophy with sparing of the sensorimotor cortex, occipital poles, and cerebellum, and offers a comprehensive view of atrophy patterns in AD.