S
Shi Yi Yang
Researcher at National Taiwan University
Publications - 5
Citations - 348
Shi Yi Yang is an academic researcher from National Taiwan University. The author has contributed to research in topics: Adenocarcinoma & Single-nucleotide polymorphism. The author has an hindex of 5, co-authored 5 publications receiving 322 citations. Previous affiliations of Shi Yi Yang include Academia Sinica.
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Journal ArticleDOI
The 5p15.33 Locus Is Associated with Risk of Lung Adenocarcinoma in Never-Smoking Females in Asia
Chao A. Hsiung,Qing Lan,Yun Chul Hong,Chien-Jen Chen,Chien-Jen Chen,Iii Dean Hosgood,I. Shou Chang,Nilanjan Chatterjee,Paul Brennan,Chen Wu,Wei Zheng,Gee-Chen Chang,Gee-Chen Chang,Tangchun Wu,Jae Yong Park,Chin-Fu Hsiao,Yeul Hong Kim,Hongbing Shen,Adeline Seow,Meredith Yeager,Ying-Huang Tsai,Young Tae Kim,Wong Ho Chow,Huan Guo,Wen Chang Wang,Sook Whan Sung,Zhibin Hu,Kuan-Yu Chen,Joohyun Kim,Ying Chen,Liming Huang,Kyoung Mu Lee,Yen Li Lo,Yu Tang Gao,Jin Hee Kim,Li Liu,Ming Shyan Huang,Tae Hoon Jung,Guangfu Jin,Neil E. Caporaso,Dianke Yu,Chang Ho Kim,Wu Chou Su,Xiao-Ou Shu,Ping Xu,In San Kim,Yuh Min Chen,Hongxia Ma,Min Shen,Sung Ick Cha,Wen Tan,Chin-Hao Chang,Jae Sook Sung,Mingfeng Zhang,Tsung-Ying Yang,Kyong Hwa Park,Jeff Yuenger,Chih-Liang Wang,Jeong Seon Ryu,Yong-Bing Xiang,Qifei Deng,Amy Hutchinson,Jun Suk Kim,Qiuyin Cai,Maria Teresa Landi,Chong-Jen Yu,Ju Yeon Park,Margaret A. Tucker,Jen Yu Hung,Chien Chung Lin,Reury Perng Perng,Paolo Boffetta,Chih Yi Chen,Kun-Chieh Chen,Shi Yi Yang,Chi Yuan Hu,Chung Kai Chang,Joseph F. Fraumeni,Stephen J. Chanock,Pan-Chyr Yang,Nathaniel Rothman,Dongxin Lin +81 more
TL;DR: Results show that genetic variation in the CLPTM1L-TERT locus of chromosome 5p15.33 is directly associated with the risk of lung cancer, most notably adenocarcinoma.
Journal ArticleDOI
R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability
Hsuan-Yu Chen,Sung-Liang Yu,Bing Ching Ho,Kang-Yi Su,Yi Chiung Hsu,Chi Sheng Chang,Yu Cheng Li,Shi Yi Yang,Pin Yen Hsu,Hao Ho,Ya Hsuan Chang,Chih Yi Chen,Hwai I. Yang,Chung Ping Hsu,Tsung-Ying Yang,Kun-Chieh Chen,Kuo-Hsuan Hsu,Jeng-Sen Tseng,Jiun Yi Hsia,Cheng Yen Chuang,Shinsheng Yuan,Mei Hsuan Lee,Chia Hsin Liu,Guan I. Wu,Chao A. Hsiung,Yuh Min Chen,Chih-Liang Wang,Ming Shyan Huang,Chong-Jen Yu,Kuan-Yu Chen,Ying-Huang Tsai,Wu Chou Su,Huei-Wen Chen,Jeremy J.W. Chen,Chien-Jen Chen,Gee-Chen Chang,Pan-Chyr Yang,Ker-Chau Li,Ker-Chau Li +38 more
TL;DR: YAP1 mutation was shown to increase the colony formation ability and invasion potential of lung cancer cells and implicated YAP1 R331W as an allele predisposed for lung adenocarcinoma with high familial penetrance.
Journal ArticleDOI
EGFR L858R Mutation and Polymorphisms of Genes related to Estrogen Biosynthesis and Metabolism in Never-smoking Female Lung Adenocarcinoma Patients
Shi Yi Yang,Tsung-Ying Yang,Kun Chieh Chen,Yao Jen Li,Yao Jen Li,Kuo-Hsuan Hsu,Chi Rne Tsai,Chih Yi Chen,Chung Ping Hsu,Jiun Yi Hsia,Cheng Yen Chuang,Ying-Huang Tsai,Kuan-Yu Chen,Ming Shyan Huang,Wu Chou Su,Yuh Min Chen,Chao A. Hsiung,Chen-Yang Shen,Gee-Chen Chang,Pan-Chyr Yang,Chien-Jen Chen,Chien-Jen Chen +21 more
TL;DR: The L858R mutation of EGFR is associated with polymorphisms of genes related to estrogen biosynthesis and metabolism in never-smoking female lung adenocarcinoma patients and the number of risk alleles of CYP17, CYP19A1, ERα, and COMT was associated with an increasing OR.
Journal ArticleDOI
Fanconi anemia genes in lung adenocarcinoma- a pathway-wide study on cancer susceptibility
Shi Yi Yang,Chia-Ni Hsiung,Yao Jen Li,Gee-Chen Chang,Ying-Huang Tsai,Kuan-Yu Chen,Ming Shyan Huang,Wu Chou Su,Yuh Min Chen,Chao A. Hsiung,Pan-Chyr Yang,Chien-Jen Chen,Pei Ei Wu,Jyh Cherng Yu,Chen-Yang Shen,Huan Ming Hsu +15 more
TL;DR: Genetic polymorphism of the FA genes is associated with inter-individual susceptibility to lung adenocarcinoma, and the association between genotypes and risk is modified by exposure to cigarette smoke.
Journal ArticleDOI
EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients.
Shi Yi Yang,Shi Yi Yang,Tsung-Ying Yang,Yao Jen Li,Yao Jen Li,Kun-Chieh Chen,Kuo Meng Liao,Kuo-Hsuan Hsu,Chi Ren Tsai,Chih Yi Chen,Chung Ping Hsu,Jiun Yi Hsia,Cheng Yen Chuang,Ying-Huang Tsai,Kuan-Yu Chen,Ming Shyan Huang,Wu Chou Su,Yuh Min Chen,Chao A. Hsiung,Chen-Yang Shen,Chen-Yang Shen,Gee-Chen Chang,Pan-Chyr Yang,Chien-Jen Chen,Chien-Jen Chen +24 more
TL;DR: It is suggested that the in‐frame deletion in EGFR exon 19 is associated with polymorphisms in DNA repair and detoxification metabolism genes in never‐smoking lung adenocarcinoma patients, especially in females.