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I. Shou Chang

Researcher at National Health Research Institutes

Publications -  13
Citations -  1481

I. Shou Chang is an academic researcher from National Health Research Institutes. The author has contributed to research in topics: Lung cancer & Genome-wide association study. The author has an hindex of 12, co-authored 13 publications receiving 1270 citations. Previous affiliations of I. Shou Chang include Georgetown University.

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Journal ArticleDOI

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Georg Ehret, +375 more
- 01 Oct 2016 - 
TL;DR: In this article, the authors identified 66 blood pressure-associated loci, of which 17 were new; 15 harbored multiple distinct association signals, and 66 index SNPs were enriched for cis-regulatory elements, particularly in vascular endothelial cells, consistent with a primary role in blood pressure control through modulation of vascular tone across multiple tissues.
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Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

Qing Lan, +133 more
- 01 Dec 2012 - 
TL;DR: It is observed that there is no evidence of association for lung cancer at 15q25 in never-smoking women in Asia, providing strong evidence that this locus is not associated with lung cancer independent of smoking.
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The 5p15.33 Locus Is Associated with Risk of Lung Adenocarcinoma in Never-Smoking Females in Asia

Chao A. Hsiung, +81 more
- 05 Aug 2010 - 
TL;DR: Results show that genetic variation in the CLPTM1L-TERT locus of chromosome 5p15.33 is directly associated with the risk of lung cancer, most notably adenocarcinoma.
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Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

Joshua N. Sampson, +448 more
TL;DR: Correlation analysis indicates that the genetic architecture of lung cancer differs between a smoking population of European ancestry and a nonsmoking Asian population, allowing for the possibility that the Genetic etiology for the same disease can vary by population and environmental exposures.
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Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

Zhaoming Wang, +383 more
TL;DR: In this article, the authors conducted an agnostic subset-based meta-analysis (association analysis based on subsets) across six distinct cancers in 34 248 cases and 45 036 controls.