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Shuang Huang
Researcher at University of Florida
Publications - 61
Citations - 6908
Shuang Huang is an academic researcher from University of Florida. The author has contributed to research in topics: Cell migration & Kinase. The author has an hindex of 34, co-authored 56 publications receiving 6506 citations. Previous affiliations of Shuang Huang include Georgia Regents University & Scripps Research Institute.
Papers
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Journal ArticleDOI
Cardiac Muscle Cell Hypertrophy and Apoptosis Induced by Distinct Members of the p38 Mitogen-activated Protein Kinase Family
Yibin Wang,Shuang Huang,Valerie P. Sah,John Ross,Joan Heller Brown,Jiahuai Han,Kenneth R. Chien +6 more
TL;DR: The direct involvement of p38 pathways in cardiac hypertrophy and apoptosis suggests a significant role for p38 signaling in the pathophysiology of heart failure.
Journal ArticleDOI
Involvement of microRNA in AU-rich element-mediated mRNA instability.
Qing Jing,Shuang Huang,Sabine Guth,Tyler Zarubin,Andrea Motoyama,Jianming Chen,Franco Di Padova,Sheng-Cai Lin,Hermann Gram,Jiahuai Han +9 more
TL;DR: In this paper, an RNAi-based screen performed in Drosophila S2 cells has revealed that Dicer1, Argonaute1 (Ago1) and Ago2, components involved in microRNA processing and function, are required for the rapid decay of mRNA containing AREs of tumor necrosis factor-alpha.
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Differential regulation of cell motility and invasion by FAK
Datsun A. Hsia,Satyajit Sujit Kumar Mitra,Christof R. Hauck,Christof R. Hauck,Christof R. Hauck,Daniel N. Streblow,Jay A. Nelson,Dusko Ilic,Shuang Huang,Erguang Li,Glen R. Nemerow,Jay Leng,Kathryn S. R. Spencer,David A. Cheresh,David D. Schlaepfer +14 more
TL;DR: It is shown that viral Src transformation of FAK−/− cells promotes integrin-stimulated motility equal to stable FAK reexpression, and a dual role for FAK in promoting cell motility and invasion through the activation of distinct signaling pathways.
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Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor
Yutaka Kato,Richard I. Tapping,Shuang Huang,Mark H. Watson,Richard J. Ulevitch,Jiing Dwan Lee +5 more
TL;DR: It is demonstrated that Bmk1 is part of a distinct MAP-kinase signalling pathway that is required for EGF-induced cell proliferation and progression through the cell cycle.
Journal ArticleDOI
Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery.
TL;DR: It is demonstrated that freshly isolated peripheral blood monocytes and T lymphocytes express very small amounts of alpha v integrins and also are resistant to adenovirus infection.