Shuying Liu

TL;DR: Results indicated that nonprogressors were differentiated by increased proliferative capacity of HIV-specific CD8+ T cells linked to enhanced effector function, and the relative absence of these functions in progressors may represent a mechanism by which HIV avoids immunological control.

TL;DR: An internally controlled real-time reverse transcriptase-initiated PCR assay that quantifies HIV-1 RNA concentrations down to 1 copy per ml of plasma and had a greater sensitivity than the other assays shown, allowing better characterization of persistent viremia in patients who are receiving antiretroviral therapy and whose HIV- 1 RNA levels are suppressed to below the detection limits of present assays.

TL;DR: Results indicate that HIV viremia induces the appearance of a subset of B cells whose function is impaired and which may be responsible for the hypergammaglobulinemia associated with HIV disease.

TL;DR: The data suggest that the persistent viremia on current antiretroviral therapy is derived, at least in part, from long-lived cells that are infected prior to initiation of therapy.

TL;DR: It is demonstrated that HIV interacts directly with B cells in both lymphoid tissues and peripheral blood, and B cells are similar to follicular dendritic cells in their capacity to serve as extracellular reservoirs for HIV-1.