Michael A. Polis

TL;DR: It is found that, although thymic function declines with age, substantial output is maintained into late adulthood and this results indicate that the adult thymus can contribute to immune reconstitution following HAART.

TL;DR: Ex vivo labeling with BrdUrd showed that CD4 and CD8 cell turnover increased after withdrawal of HAART and correlated with viral load whereas lymphocyte turnover decreased after reinitiation of drug treatment, and Virologic relapse occurs rapidly in patients who discontinue suppressive drug therapy.

TL;DR: An internally controlled real-time reverse transcriptase-initiated PCR assay that quantifies HIV-1 RNA concentrations down to 1 copy per ml of plasma and had a greater sensitivity than the other assays shown, allowing better characterization of persistent viremia in patients who are receiving antiretroviral therapy and whose HIV- 1 RNA levels are suppressed to below the detection limits of present assays.

TL;DR: Cryptococcosis in patients with the acquired immunodeficiency syndrome is a debilitating disease that does not respond to conventional therapy; earlier diagnosis or long-term suppressive therapy may improve the prognosis.

TL;DR: This fourth edition of the guidelines for preventing opportunistic infections (OIs) among persons infected with human immunodeficiency virus (HIV) is intended for clinicians and other health-care providers who care for HIV-infected persons.