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Si-Xue Cheng

Researcher at Wuhan University

Publications -  238
Citations -  12634

Si-Xue Cheng is an academic researcher from Wuhan University. The author has contributed to research in topics: Drug carrier & Micelle. The author has an hindex of 54, co-authored 236 publications receiving 10754 citations. Previous affiliations of Si-Xue Cheng include Sichuan University & University of South China.

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Fabrication of a novel pH-sensitive glutaraldehyde cross-linked pectin nanogel for drug delivery

TL;DR: In vitro drug-release behavior of the drug-loaded nanogel particles in three kinds of media, i.e., simulated gastric fluid, simulated intestine fluid and simulated colon fluid, showed a faster release at a high pH, and the release could be further accelerated in the presence of pectinolytic enzyme, indicating that thenanogel may be used for colon-specific drug delivery.
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Cyclodextrin-Responsive Micelles Based on Poly(ethylene glycol)–Polypeptide Hybrid Copolymers as Drug Carriers

TL;DR: The result shows that the release of the entrapped drug doxorubicin (DOX) from the micelles could be accelerated by the addition of β-CD, and are expected to have great potential in controlled drug release applications.
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A Dual-Targeting Delivery System for Effective Genome Editing and In Situ Detecting Related Protein Expression in Edited Cells

TL;DR: A dual-targeting delivery system based on polymer/inorganic hybrid nanoparticles to realize highly efficient genome editing in targeted tumor cells as well as in situ detection on the related protein expression in edited cells simultaneously is developed.
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Yolk‐Shell Structured Nanoflowers Induced Intracellular Oxidative/Thermal Stress Damage for Cancer Treatment

TL;DR: Owing to the urchin‐like structured shell, the novel structured CLMNF exhibits favorable inhibition of tumors in vivo, indicating that using nanoflowers to induce intracellular oxidative/thermal stress damage could be a promising strategy for anticancer treatment.
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Hierarchical Micro‐/Nanostructures from Human Hair for Biomedical Applications

TL;DR: The multifaceted materials described here might provide a new tool for addressing biomedical challenges and display attentional abilities in the aspects of light absorption and free radical scavenging.