S
Si-Xue Cheng
Researcher at Wuhan University
Publications - 238
Citations - 12634
Si-Xue Cheng is an academic researcher from Wuhan University. The author has contributed to research in topics: Drug carrier & Micelle. The author has an hindex of 54, co-authored 236 publications receiving 10754 citations. Previous affiliations of Si-Xue Cheng include Sichuan University & University of South China.
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Journal ArticleDOI
Fabrication of a novel pH-sensitive glutaraldehyde cross-linked pectin nanogel for drug delivery
Cong Chang,Zong-Chun Wang,Chang-Yun Quan,Han Cheng,Si-Xue Cheng,Xian-Zheng Zhang,Ren-Xi Zhuo +6 more
TL;DR: In vitro drug-release behavior of the drug-loaded nanogel particles in three kinds of media, i.e., simulated gastric fluid, simulated intestine fluid and simulated colon fluid, showed a faster release at a high pH, and the release could be further accelerated in the presence of pectinolytic enzyme, indicating that thenanogel may be used for colon-specific drug delivery.
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Cyclodextrin-Responsive Micelles Based on Poly(ethylene glycol)–Polypeptide Hybrid Copolymers as Drug Carriers
TL;DR: The result shows that the release of the entrapped drug doxorubicin (DOX) from the micelles could be accelerated by the addition of β-CD, and are expected to have great potential in controlled drug release applications.
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A Dual-Targeting Delivery System for Effective Genome Editing and In Situ Detecting Related Protein Expression in Edited Cells
TL;DR: A dual-targeting delivery system based on polymer/inorganic hybrid nanoparticles to realize highly efficient genome editing in targeted tumor cells as well as in situ detection on the related protein expression in edited cells simultaneously is developed.
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Yolk‐Shell Structured Nanoflowers Induced Intracellular Oxidative/Thermal Stress Damage for Cancer Treatment
Miao-Deng Liu,Deng-Ke Guo,Run-Yao Zeng,Jing-Jie Ye,Shi-Bo Wang,Chu-Xin Li,Yun-Xia Sun,Si-Xue Cheng,Xian-Zheng Zhang +8 more
TL;DR: Owing to the urchin‐like structured shell, the novel structured CLMNF exhibits favorable inhibition of tumors in vivo, indicating that using nanoflowers to induce intracellular oxidative/thermal stress damage could be a promising strategy for anticancer treatment.
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Hierarchical Micro‐/Nanostructures from Human Hair for Biomedical Applications
TL;DR: The multifaceted materials described here might provide a new tool for addressing biomedical challenges and display attentional abilities in the aspects of light absorption and free radical scavenging.