Si-Xue Cheng

TL;DR: End-functionalized poly/oligo(epsilon-caprolactone)s were synthesized through the ring-opening polymerization of epsilon-caproactone initiated by cholesterol with a hydroxyl group using a convenient melting-emulsion method.

TL;DR: The results show the hydrolytic degradation rate increases with increasing content of hydrophilic PAMAM-OH core, and the catalytic effect of Pseudomonas cepacia lipase on the degradation of PCL branches and the hydrophilicity that depends on the polymer composition.

TL;DR: The study on immunostimulatory effects of different treatments showed that BSO/CXB@BNP treatment resulted in the lowest concentration of interleukin 10, a cytokine related to tumor development, suggesting the nanoparticulate drug delivery platform developed in this study has promising applications in multiple drug delivery to overcome drug resistance in tumor treatments.

TL;DR: It was demonstrated that this modification strategy can realize controlled growth of porphyrin MOF on a series of organic and inorganic nanostructures, such as polydopamine (PDA) nanoparticles, PDA@Pt nanoparticles), graphene oxide sheets, and Au nanorods.

TL;DR: In vitro study showed that BCMC/CaCO3/DOX/TQR nanoparticles exhibited obviously enhanced cell uptake and nuclear localization as compared with the free DOX and the single-drug loaded nanoparticles because of the efficient inhibition of P-glycop protein mediated efflux.