Si-Xue Cheng

TL;DR: The study on the drug release properties shows the macroporous hydrogels exhibit modulated release in response to temperature, and the PNIPA gels thus prepared have remarkably larger swelling ratios below their lower critical solution temperature (LCST), and exhibit much faster response rates as the temperature is raised above their LCST.

TL;DR: The study on in vitro cell inhibition effects showed that the cell viability decreased with increasing DOX amount loaded in alginate/CaCO(3)/DNA/DOX nanoparticles, and the nanoparticles prepared in this study have promising applications in gene and drug delivery.

TL;DR: Compared with the traditional tumor chemotherapy, the integrated theranostic nanoplatform developed not only improved the tumor specific cytotoxicity but also stimulated antitumor immune responses during the treatment.

TL;DR: In vivo data show that the pro‐NTA activation strategy could selectively brighten solid tumors and detect invisible lymph node metastases with high specificity, and guarantee a more efficient therapeutic performance compared to monotherapy.

TL;DR: A new smart and hype-responsive polyprodrug platform with five key elements, which has the following unique characteristics: high and constant drug loading, excellent tumor-targeting performance, hyper-fast redox-responsive drug release, long blood circulation and significant inhibition of tumor growth without side effects.