S
Siddappa N. Byrareddy
Researcher at University of Nebraska Medical Center
Publications - 152
Citations - 7188
Siddappa N. Byrareddy is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 22, co-authored 121 publications receiving 4599 citations. Previous affiliations of Siddappa N. Byrareddy include Emory University & Harvard University.
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Journal ArticleDOI
Relationship of menstrual cycle and vaginal infection in female rhesus macaques challenged with repeated, low doses of SIVmac251.
Monica Morris,Siddappa N. Byrareddy,Francois Villinger,Tara Henning,Katherine Butler,Aftab A. Ansari,Janet M. McNicholl,Ellen N. Kersh +7 more
TL;DR: Varying susceptibility during menstrual cycling could be a factor for S(H)IV infection risk in female rhesus macaques, and vaginal SIV infection time points relative to the menstrual cycle are determined.
Journal ArticleDOI
Human Immunodeficiency Virus and Severe Acute Respiratory Syndrome Coronavirus 2 Coinfection: A Systematic Review of the Literature and Challenges.
Raj H. Patel,Arpan Acharya,Hitendra S. Chand,Mahesh Mohan,Siddappa N. Byrareddy,Siddappa N. Byrareddy +5 more
TL;DR: A systematic review of the literature reporting cases of HIV and SARS-CoV-2 coinfection, and examine trends of clinical outcomes among coinfected patients is presented in this article.
Journal ArticleDOI
Species-Specific Differences in the Expression and Regulation of α4β7 Integrin in Various Nonhuman Primates
Siddappa N. Byrareddy,Neil Sidell,James Arthos,Claudia Cicala,Chunxia Zhao,Dawn M. Little,Paul Dunbar,Gui X. Yang,Keely Pierzchalski,Maureen A. Kane,Ann E. Mayne,Byeongwoon Song,Marcelo A. Soares,Francois Villinger,Anthony S. Fauci,Aftab A. Ansari +15 more
TL;DR: It is reported that CD4+ T cells from PM constitutively express significantly higher levels of α4β7 than RM or SM, and it is proposed that differences in the regulation and expression of β7 may explain the differences in susceptibility and SIV disease progression in these NHP models.
Journal ArticleDOI
Optimizing intracellular signaling domains for CAR NK cells in HIV immunotherapy: a comprehensive review.
TL;DR: The role of NK cells in HIV and the mechanisms of actions of HIV-targeting CAR strategies are discussed and signal transduction and its application to CAR NK cell strategies to develop new combinations of CAR intracellular domains and to improve CAR NK signaling and cytotoxic functions are reviewed.
Journal ArticleDOI
Passive immunization of macaques with polyclonal anti-SHIV IgG against a heterologous tier 2 SHIV: outcome depends on IgG dose
Anton M Sholukh,Anton M Sholukh,Siddappa N. Byrareddy,Siddappa N. Byrareddy,Vivekanandan Shanmuganathan,Girish Hemashettar,Samir K. Lakhashe,Samir K. Lakhashe,Robert A. Rasmussen,Jennifer D. Watkins,Hemant K. Vyas,Hemant K. Vyas,Swati Thorat,Tania Brandstoetter,Muhammad Mukhtar,Muhammad Mukhtar,John K. Yoon,Francis J. Novembre,Francis J. Novembre,Francois Villinger,Francois Villinger,Gary Landucci,Donald N. Forthal,Sarah J. Ratcliffe,Iskra Tuero,Marjorie Robert-Guroff,Victoria R. Polonis,Miroslawa Bilska,David C. Montefiori,Welkin E. Johnson,Hildegund C.J. Ertl,Ruth M. Ruprecht,Ruth M. Ruprecht +32 more
TL;DR: Primate model data suggest a dual role for polyclonal anti-HIV-1 Abs depending on plasma levels upon virus encounter, and in vitro results demonstrated complement-mediated Ab-dependent enhancement of infection at concentrations similar to those observed in plasmas of RMs treated with 25 mg/kg of SHIVIG.