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Simon Shaw

Researcher at Technical University of Denmark

Publications -  8
Citations -  3695

Simon Shaw is an academic researcher from Technical University of Denmark. The author has contributed to research in topics: Gene cluster & Cas9. The author has an hindex of 7, co-authored 7 publications receiving 1724 citations.

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antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

TL;DR: AntiSMASH 5 adds detection rules for clusters encoding the biosynthesis of acyl-amino acids, β-lactones, fungal RiPPs, RaS-Ri PPs, polybrominated diphenyl ethers, C-nucleosides, PPY-like ketones and lipolanthines and provides more detailed predictions for type II polyketide synthase-encoding gene clusters.
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antiSMASH 6.0: improving cluster detection and comparison capabilities.

TL;DR: antiSMASH as mentioned in this paper is the most widely used tool for detecting and characterising biosynthetic gene clusters (BGCs) in bacteria and fungi, and it is updated version 6 of antiSMASH.
Journal ArticleDOI

BiG-FAM : the biosynthetic gene cluster families database

TL;DR: BiG-FAM is presented, a database of 29,955 GCFs capturing the global diversity of 1,225,071 BGCs predicted from 209,206 publicly available microbial genomes and metagenome-assembled genomes (MAGs).
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The antiSMASH database version 3 : increased taxonomic coverage and new query features for modular enzymes

TL;DR: The antiSMASH database as discussed by the authors provides a means to access and query precomputed anti-SMASH-5.2-detected biosynthetic gene clusters from representative, publicly available, high-quality microbial genomes via an interactive graphical user interface.