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Stephan Ripke
Researcher at Broad Institute
Publications - 311
Citations - 80990
Stephan Ripke is an academic researcher from Broad Institute. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 97, co-authored 278 publications receiving 63650 citations. Previous affiliations of Stephan Ripke include Icahn School of Medicine at Mount Sinai & University of Texas Southwestern Medical Center.
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Journal ArticleDOI
The Relationship Between the Recognition of Basic Emotions and Negative Symptoms in Individuals With Schizophrenia Spectrum Disorders – An Exploratory Study
Marco Zierhut,Kerem Böge,Niklas Bergmann,Inge Hahne,Alice Braun,Julia Kraft,Thi Minh Tam Ta,Stephan Ripke,Malek Bajbouj,Eric Hahn +9 more
TL;DR: In this paper , correlation analyses were conducted between seven different negative symptom subdomains of the Positive and Negative Syndrome Scale (PANSS) and the accuracy and latency in recognizing the six basic emotions (anger, disgust, fear, happiness, sadness, surprise) using the Emotion Recognition Task (ERT) of the Cambridge Neuropsychological Test Automated Battery (CANTAB).
Journal ArticleDOI
How alcohol makes the epigenetic clock tick faster and the clock reversing effect of abstinence
Tristan Zindler,Helge Frieling,Lena Fliedner,Ilya M. Veer,Alexandra Neyazi,Swapnil Awasthi,Stephan Ripke,Henrik Walter,Eva Friedel +8 more
TL;DR: It is found that ageing was accelerated by 3.64 years in AUD patients compared with the CON group according to Levine's DNAm PhenoAge and the first evidence for a recovery of this effect upon abstinence from alcohol is provided.
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Increasing sample diversity in psychiatric genetics - Introducing a new cohort of patients with schizophrenia and controls from Vietnam - Results from a pilot study.
Van Tuan Nguyen,Alice Braun,Julia Kraft,Thi Minh Tam Ta,Georgia Panagiotaropoulou,V P Nguyen,T H Nguyen,T H Nguyen,Vassily Trubetskoy,C T Le,T T H Le,X T Pham,Isabella Heuser-Collier,N H Lam,Kerem Böge,I.M. Hahne,Malek Bajbouj,M. M. Zierhut,Eric Hahn,Stephan Ripke,Stephan Ripke +20 more
TL;DR: In this article, a large-scale data collection in Hanoi, Vietnam, contribute to international efforts to diversify ancestry in SCZ genetic research and examine the transferability of SCZ-PRS to individuals of Vietnamese Kinh ancestry.
Journal ArticleDOI
45. genome-wide association study of borderline personality disorder - an update from the international borderline genomics consortium
Stephanie H. Witt,Swapnil Awasthi,I. F. Consortium,Marcella Rietschel,Stephan Ripke,Fabian Streit +5 more
Journal ArticleDOI
Non-random mating, parent-of-origin, and maternal–fetal incompatibility effects in schizophrenia
Yunjung Kim,Stephan Ripke,George Kirov,Pamela Sklar,Shaun Purcell,Michael John Owen,Michael Conlon O'Donovan,Patrick F. Sullivan +7 more
TL;DR: This work evaluated the hypothesis that maternal-fetal HLA incompatibility may increase risk for schizophrenia using eight classical HLA loci and found no evidence for non-random mating in the parents of individuals with schizophrenia in terms of MHC genotypes or schizophrenia risk profile scores, and evidence of non- random mating that appeared mostly to be driven by ancestry.