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Stephan Ripke
Researcher at Broad Institute
Publications - 311
Citations - 80990
Stephan Ripke is an academic researcher from Broad Institute. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 97, co-authored 278 publications receiving 63650 citations. Previous affiliations of Stephan Ripke include Icahn School of Medicine at Mount Sinai & University of Texas Southwestern Medical Center.
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Journal ArticleDOI
Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p
Daniel J. Weiner,Emi Ling,Serkan Erdin,Derek J. C. Tai,Rachita Yadav,Jakob Grove,Jack Fu,Ajay Nadig,Nikolas Baya,Jonas Bybjerg-Grauholm,Preben Bo Mortensen,Thomas Werge,Ditte Demontis,Ole Mors,Merete Nordentoft,Thomas Damm Als,M. Baekvad-Hansen,Anders Rosengren,Alexandra Havdahl,Anne Hedemand,Aarno Palotie,Aravinda Chakravarti,Dan E. Arking,Arvis Sulovari,Anna Starnawska,Bhooma Thiruvahindrapuram,Christiaan de Leeuw,Caitlin E. Carey,Christine Ladd-Acosta,C. van der Merwe,Bernie Devlin,Edwin H. Cook,Evan E. Eichler,Elizabeth Corfield,Gwen C. Dieleman,Gerard D. Schellenberg,Hakon Hakonarson,Hilary Coon,Isabel Dziobek,Jacob A. S. Vorstman,Jessica B. Girault,James S. Sutcliffe,Jinjie Duan,John I. Nurnberger,Joachim Hallmayer,Joseph D. Buxbaum,Joseph Piven,Lauren A. Weiss,Lea K. Davis,Magdalena Janecka,Manuel Mattheisen,Matthew W. State,Michael Gill,Mark J. Daly,Mohammed Uddin,Ole Andreassen,Peter Szatmari,Phil Lee,Richard Anney,Stephan Ripke,F. Kyle Satterstrom,Susan L. Santangelo,Susanna Campbell Kuo,Ludger Tebartz van Elst,Thomas Rolland,T. Bougeron,Tinca J. C. Polderman,Tychele N. Turner,Jacky Underwood,V Manikandan,Vamsee Pillalamarri,Varun Warrier,Alexandra Philipsen,Andreas Reif,Anke Hinney,Bru Cormand,Claiton H.D. Bau,Diego L. Rovaris,Edmund J.S. Sonuga-Barke,Eugenio H. Grevet,Giovanni Abrahão Salum,Henrik Larsson,Jan K. Buitelaar,Jan Haavik,James Cooke McGough,Jonna Kuntsi,Josephine Elia,Klaus-Peter Lesch,Marieke Klein,Mark A. Bellgrove,Martin Tesli,Patrick W. L. Leung,Pedro Mario Pan,Søren Dalsgaard,Sandra K. Loo,Sarah E. Medland,Stephen V. Faraone,Ted Reichborn-Kjennerud,Tobias Banaschewski,Ziarih Hawi,Sabina Berretta,Evan Z. Macosko,Jonathan Sebat,Luke J. O’Connor,David M. Hougaard,Anders D. Børglum,Michael E. Talkowski,Steven A. McCarroll,Elise B. Robinson +108 more
TL;DR: In this article , the authors identify the 33-Mb p-arm of chromosome 16 (16p) as harboring the greatest excess of autism's common polygenic influences, including the mechanistically cryptic and autism-associated 16p11.2 copy number variant.
Journal ArticleDOI
A genome-wide association study points to multiple loci predicting antidepressant treatment outcome in depression
Marcus Ising,Susanne Lucae,Elisabeth B. Binder,Thomas Bettecken,Manfred Uhr,Stephan Ripke,Martin A. Kohli,Johannes M. Hennings,S. Horstmann,Stefan Kloiber,Andreas Menke,Brigitta Bondy,Rainer Rupprecht,Katharina Domschke,Bernhard T. Baune,Volker Arolt,A. J. Rush,Florian Holsboer,Bertram Müller-Myhsok +18 more
Journal ArticleDOI
Erratum to: Genetic risk variants for social anxiety (American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, (2017), 174, 2, (120-131), 10.1002/ajmg.b.32520)
Murray B. Stein,Chia-Yen Chen,Sonia Jain,Kevin P. Jensen,Feng He,Steven G. Heeringa,Ronald C. Kessler,Adam X. Maihofer,Matthew K. Nock,Stephan Ripke,Xiaoying Sun,Michael L. Thomas,Robert J. Ursano,Jordan W. Smoller,Joel Gelernter +14 more
TL;DR: It has been brought to the authors' attention by the authors that Table III and Figure 2 errors occurred during the revision process.
Posted ContentDOI
A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium
Christian R. Marshall,Daniel P. Howrigan,Daniel P. Howrigan,Daniele Merico,Bhooma Thiruvahindrapuram,Wenting Wu,Douglas S. Greer,Danny Antaki,Aniket Shetty,Peter Holmans,Peter Holmans,Dalila Pinto,Madhusudan Gujral,William M. Brandler,Dheeraj Malhotra,Dheeraj Malhotra,Zhouzhi Wang,Karin V. Fuentes Fajarado,Stephan Ripke,Stephan Ripke,Ingrid Agartz,Ingrid Agartz,Esben Agerbo,Esben Agerbo,Margot Albus,Madeline Alexander,Farooq Amin,Farooq Amin,Joshua R. Atkins,Silviu Alin Bacanu,Richard A. Belliveau,Sarah E. Bergen,Sarah E. Bergen,Marcelo Bertalan,Marcelo Bertalan,Elizabeth Bevilacqua,Tim B. Bigdeli,Donald W. Black,Richard Bruggeman,Nancy G. Buccola,Randy L. Buckner,Brendan Bulik-Sullivan,Brendan Bulik-Sullivan,William Byerley,Wiepke Cahn,Guiqing Cai,Murray J. Cairns,Dominique Campion,Rita M. Cantor,Vaughan J. Carr,Noa Carrera,Stanley V. Catts,Kimberley D. Chambert,Wei Cheng,C. Robert Cloninger,David Cohen,Paul Cormican,Nicholas John Craddock,Nicholas John Craddock,Benedicto Crespo-Facorro,James J. Crowley,David Curtis,David Curtis,Michael Davidson,Kenneth L. Davis,Franziska Degenhardt,Jurgen Del Favero,Lynn E. DeLisi,Ditte Demontis,Ditte Demontis,Dimitris Dikeos,Timothy G. Dinan,Srdjan Djurovic,Srdjan Djurovic,Gary Donohoe,Gary Donohoe,Elodie Drapeau,Jubao Duan,Jubao Duan,Frank Dudbridge,Peter Eichhammer,Johan G. Eriksson,Johan G. Eriksson,Valentina Escott-Price,Laurent Essioux,Ayman H. Fanous,Kai-How Farh,Martilias S. Farrell,Josef Frank,Lude Franke,Robert Freedman,Nelson B. Freimer,Joseph I. Friedman,Andreas J. Forstner,Menachem Fromer,Giulio Genovese,Lyudmila Georgieva,Elliot S. Gershon,Ina Giegling,Ina Giegling,Paola Giusti-Rodríguez,Stephanie Godard,Jacqueline I. Goldstein,Jacqueline I. Goldstein,Jacob Gratten,Lieuwe de Haan,Marian L. Hamshere,Mark Hansen,Thomas Hansen,Thomas Hansen,Vahram Haroutunian,Vahram Haroutunian,Annette M. Hartmann,Frans Henskens,Stefan Herms,Stefan Herms,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Per Hoffmann,Per Hoffmann,A. Hofman,Mads V. Hollegaard,David M. Hougaard,Hailiang Huang,Hailiang Huang,Masashi Ikeda,Inge Joa,K Kähler Anna,René S. Kahn,Luba Kalaydjieva,Juha Karjalainen,David J. Kavanagh,Matthew C. Keller,Brian Kelly,James L. Kennedy,James L. Kennedy,Yunjung Kim,James A. Knowles,Bettina Konte,Claudine Laurent,Phil Lee,Phil Lee,S. Hong Lee,Sophie E. Legge,Bernard Lerer,Deborah L. Levy,Deborah L. Levy,Kung-Yee Liang,Jeffrey A. Lieberman,Jouko Lönnqvist,Carmel M. Loughland,Patrik K. E. Magnusson,Brion S. Maher,Wolfgang Maier,Jacques Mallet,Manuel Mattheisen,Morten Mattingsdal,Robert W. McCarley,Colm McDonald,Andrew M. McIntosh,Sandra Meier,Carin J. Meijer,Ingrid Melle,Ingrid Melle,Raquelle I. Mesholam-Gately,Raquelle I. Mesholam-Gately,Andres Metspalu,Patricia T. Michie,Lili Milani,Vihra Milanova,Younes Mokrab,Derek W. Morris,Derek W. Morris,Ole Mors,Ole Mors,Ole Mors,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Kieran C. Murphy,Robin M. Murray,Inez Myin-Germeys,Igor Nenadic,Deborah A. Nertney,Gerald Nestadt,Kristin K. Nicodemus,Laura Nisenbaum,Annelie Nordin,Eadbhard O' Callaghan,Colm O. Dushlaine,Sang-Yun Oh,Ann Olincy,Line Olsen,Line Olsen,F. Anthony O’ Neill,Jim van Os,Jim van Os,Christos Pantelis,George N. Papadimitriou,Elena Parkhomenko,Michele T. Pato,Tiina Paunio,Diana O. Perkins,Tune H. Pers,Tune H. Pers,Tune H. Pers,Olli Pietiläinen,Olli Pietiläinen,Jonathan Pimm,Andrew Pocklington,John Powell,Alkes L. Price,Alkes L. Price,Ann E. Pulver,Shaun Purcell,Digby Quested,Henrik B. Rasmussen,Henrik B. Rasmussen,Abraham Reichenberg,Mark Reimers,Alexander Richards,Alexander Richards,Joshua L. Roffman,Panos Roussos,Douglas M. Ruderfer,Douglas M. Ruderfer,Veikko Salomaa,Alan R. Sanders,Alan R. Sanders,Adam Savitz,Ulrich Schall,Thomas G. Schulze,Thomas G. Schulze,Sibylle G. Schwab,Edward M. Scolnick,Rodney J. Scott,Larry J. Seidman,Larry J. Seidman,Jianxin Shi,Jeremy M. Silverman,Jeremy M. Silverman,Jordan W. Smoller,Jordan W. Smoller,Erik Söderman,Chris C. A. Spencer,Eli A. Stahl,Eli A. Stahl,Eric Strengman,Eric Strengman,Jana Strohmaier,T. Scott Stroup,Jaana Suvisaari,Dragan M. Svrakic,Jin P. Szatkiewicz,Srinivas Thirumalai,Paul A. Tooney,Juha Veijola,Peter M. Visscher,John L. Waddington,Dermot Walsh,Bradley T. Webb,Mark Weiser,Dieter B. Wildenauer,Nigel Williams,Stephanie Williams,Stephanie H. Witt,Aaron R. Wolen,Brandon Wormley,Naomi R. Wray,Jing Qin Wu,Clement C. Zai,Clement C. Zai,Rolf Adolfsson,Ole A. Andreassen,Ole A. Andreassen,Douglas Blackwood,Anders D. Børglum,Elvira Bramon,Joseph D. Buxbaum,Sven Cichon,David A. Collier,David A. Collier,Aiden Corvin,Mark J. Daly,Mark J. Daly,Ariel Darvasi,Enrico Domenici,Tõnu Esko,Pablo V. Gejman,Pablo V. Gejman,Michael Gill,Hugh Gurling,Christina M. Hultman,Nakao Iwata,Assen Jablensky,Erik G. Jönsson,Erik G. Jönsson,Kenneth S. Kendler,George Kirov,Jo Knight,Jo Knight,Douglas F. Levinson,Qingqin S. Li,Steven A. McCarroll,Steven A. McCarroll,Andrew McQuillin,Jennifer L. Moran,Preben Bo Mortensen,Preben Bo Mortensen,Bryan J. Mowry,Bryan J. Mowry,Markus M. Nöthen,Roel A. Ophoff,Roel A. Ophoff,Roel A. Ophoff,Michael John Owen,Michael John Owen,Aarno Palotie,Aarno Palotie,Aarno Palotie,Carlos N. Pato,Tracey L. Petryshen,Tracey L. Petryshen,Danielle Posthuma,Danielle Posthuma,Danielle Posthuma,Marcella Rietschel,Brien P. Riley,Dan Rujescu,Dan Rujescu,Pamela Sklar,David St Clair,James T.R. Walters,Thomas Werge,Thomas Werge,Thomas Werge,Patrick F. Sullivan,Patrick F. Sullivan,Michael Conlon O'Donovan,Michael Conlon O'Donovan,Stephen W. Scherer,Stephen W. Scherer,Benjamin M. Neale,Jonathan Sebat +343 more
TL;DR: In this article, a centralized analysis pipeline was applied to a SCZ cohort of 21,094 cases and 20,227 controls and the authors observed a global enrichment of CNV burden in cases (OR=1.11, P=5.7e −15 ), which persisted after excluding loci implicated in previous studies.
Journal ArticleDOI
Common Genetic Variation And Age at Onset Of Anorexia Nervosa
Hunna J. Watson,Hunna J. Watson,Hunna J. Watson,Laura M. Thornton,Zeynep Yilmaz,Jessica H. Baker,Jonathan R. I. Coleman,Jonathan R. I. Coleman,Roger A.H. Adan,Roger A.H. Adan,Lars Alfredsson,Ole A. Andreassen,Helga Ask,Wade H. Berrettini,Michael Boehnke,Ilka Boehm,Claudette Boni,Katharina Buehren,Josef Bulant,Roland Burghardt,Xiao Chang,Sven Cichon,Sven Cichon,Sven Cichon,Roger D. Cone,Philippe Courtet,Scott J. Crow,James J. Crowley,James J. Crowley,Unna N. Danner,Martina de Zwaan,George Dedoussis,Janiece E. DeSocio,Danielle M. Dick,Dimitris Dikeos,Christian Dina,Srdjan Djurovic,Srdjan Djurovic,Monika Dmitrzak-Weglarz,Elisa Docampo-Martinez,Philibert Duriez,Karin Egberts,Stefan Ehrlich,Johan G. Eriksson,Johan G. Eriksson,Geòrgia Escaramís,Tõnu Esko,Tõnu Esko,Xavier Estivill,Anne Farmer,Fernando Fernández-Aranda,Manfred M. Fichter,Manuel Föcker,Lenka Foretova,Andreas J. Forstner,Andreas J. Forstner,Andreas J. Forstner,Oleksandr Frei,Oleksandr Frei,Steven Gallinger,Ina Giegling,Johanna Giuranna,Fragiskos Gonidakis,Philip Gorwood,Mònica Gratacòs,Sébastien Guillaume,Yiran Guo,Hakon Hakonarson,Hakon Hakonarson,Joanna Hauser,Alexandra Havdahl,Johannes Hebebrand,Sietske G. Helder,Stefan Herms,Stefan Herms,Beate Herpertz-Dahlmann,Wolfgang Herzog,Anke Hinney,James I. Hudson,Hartmut Imgart,Stephanie Jamain,Vladimir Janout,Susana Jiménez-Murcia,Ian Jones,Antonio Julià,Gursharan Kalsi,Deborah Kaminská,Jaakko Kaprio,Leila Karhunen,Martien J H Kas,Martien J H Kas,Pamela K. Keel,James L. Kennedy,James L. Kennedy,Anna Keski-Rahkonen,Kirsty Kiezebrink,Lars Klareskog,Kelly L. Klump,Gun Peggy Knudsen,Maria La Via,Stephanie Le Hellard,Stephanie Le Hellard,Marion Leboyer,Dong Li,Lisa Lilenfeld,Bochao Lin,Jolanta Lissowska,Jurjen J. Luykx,Pierre J. Magistretti,Pierre J. Magistretti,Mario Maj,Sara Marsal,Christian R. Marshall,Morten Mattingsdal,Ingrid Meulenbelt,Nadia Micali,Karen S. Mitchell,Alessio Maria Monteleone,Palmiero Monteleone,Richard M. Myers,Marie Navratilova,Ionna Ntalla,Julie K. O'Toole,Roel A. Ophoff,Roel A. Ophoff,Leonid Padyukov,Jacques Pantel,Hana Papežová,Dalila Pinto,Anu Raevuori,Nicolas Ramoz,Ted Reichborn-Kjennerud,Ted Reichborn-Kjennerud,Valdo Ricca,Valdo Ricca,Samuli Ripatti,Stephan Ripke,Stephan Ripke,Stephan Ripke,Franziska Ritschel,Marion Roberts,Alessandro Rotondo,Dan Rujescu,Filip Rybakowski,André Scherag,Stephen W. Scherer,Stephen W. Scherer,Ulrike Schmidt,Ulrike Schmidt,Laura J. Scott,Jochen Seitz,Yasmina Silén,Lenka Slachtova,P. Eline Slagboom,Margarita Ct. Slof-Op 't Landt,Agnieszka Słopień,Sandro Sorbi,Beata Świątkowska,Alfonso Tortorella,Federica Tozzi,Janet Treasure,Janet Treasure,Artemis Tsitsika,Marta Tyszkiewicz-Nwafor,Konstantinos Tziouvas,Annemarie A. van Elburg,Eric F. van Furth,Esther Walton,Elisabeth Widen,Stephanie Zerwas,Stephan Zipfel,Andrew W. Bergen,Joseph M. Boden,Harry Brandt,Steven Crawford,Katherine A. Halmi,L. John Horwood,Craig Johnson,Allan S. Kaplan,Allan S. Kaplan,Walter H. Kaye,James E. Mitchell,Catherine M. Olsen,John F. Pearson,Nancy L. Pedersen,Michael Strober,Michael Strober,Thomas Werge,David C. Whiteman,D. Blake Woodside,Scott D. Gordon,Sarah Maguire,Sarah Maguire,Janne Tidselbak Larsen,Janne Tidselbak Larsen,Richard Parker,Liselotte Petersen,Liselotte Petersen,Jennifer Jordan,Martin A. Kennedy,Tracey D. Wade,Andreas Birgegård,Paul Lichtenstein,Mikael Landén,Mikael Landén,Nicholas G. Martin,Preben Bo Mortensen,Preben Bo Mortensen,Gerome Breen,Gerome Breen,Cynthia M. Bulik,Cynthia M. Bulik +211 more
TL;DR: Early- and typical-onset AN showed distinct genetic correlation patterns with putative risk factors for AN, which provide evidence consistent with a common variant genetic basis for age at onset and implicate biological pathways regulating menarche and reproduction.