V
Vassily Trubetskoy
Researcher at Charité
Publications - 18
Citations - 5123
Vassily Trubetskoy is an academic researcher from Charité. The author has contributed to research in topics: Genome-wide association study & Major depressive disorder. The author has an hindex of 10, co-authored 15 publications receiving 2910 citations. Previous affiliations of Vassily Trubetskoy include Harvard University & Broad Institute.
Papers
More filters
Journal ArticleDOI
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Naomi R. Wray,Stephan Ripke,Stephan Ripke,Stephan Ripke,Manuel Mattheisen,Maciej Trzaskowski,Enda M. Byrne,Abdel Abdellaoui,Mark Adams,Esben Agerbo,Esben Agerbo,Tracy Air,Till M.F. Andlauer,Silviu Alin Bacanu,Marie Bækvad-Hansen,Marie Bækvad-Hansen,Aartjan F.T. Beekman,Tim B. Bigdeli,Elisabeth B. Binder,Elisabeth B. Binder,Douglas Blackwood,Julien Bryois,Henriette N. Buttenschøn,Henriette N. Buttenschøn,Jonas Bybjerg-Grauholm,Jonas Bybjerg-Grauholm,Na Cai,Na Cai,Enrique Castelao,Jane H. Christensen,Jane H. Christensen,Toni-Kim Clarke,Jonathan I.R. Coleman,Lucía Colodro-Conde,Baptiste Couvy-Duchesne,Nicholas John Craddock,Gregory E. Crawford,Cheynna A. Crowley,Hassan S. Dashti,Hassan S. Dashti,Gail Davies,Ian J. Deary,Franziska Degenhardt,Eske M. Derks,Nese Direk,Nese Direk,Conor V. Dolan,Erin C. Dunn,Erin C. Dunn,Thalia C. Eley,Nicholas Eriksson,Valentina Escott-Price,Farnush Hassan Farhadi Kiadeh,Hilary K. Finucane,Hilary K. Finucane,Andreas J. Forstner,Josef Frank,Helena Gaspar,Michael Gill,Paola Giusti-Rodríguez,Fernando S. Goes,Scott D. Gordon,Jakob Grove,Lynsey S. Hall,Lynsey S. Hall,Eilis Hannon,Christine Søholm Hansen,Christine Søholm Hansen,Thomas Hansen,Thomas Hansen,Stefan Herms,Stefan Herms,Ian B. Hickie,Per Hoffmann,Per Hoffmann,Georg Homuth,Carsten Horn,Jouke-Jan Hottenga,David M. Hougaard,David M. Hougaard,Ming Hu,Craig L. Hyde,Marcus Ising,Rick Jansen,Fulai Jin,Eric Jorgenson,James A. Knowles,Isaac S. Kohane,Isaac S. Kohane,Isaac S. Kohane,Julia Kraft,Warren W. Kretzschmar,Jesper Krogh,Zoltán Kutalik,Zoltán Kutalik,Jacqueline M. Lane,Jacqueline M. Lane,Yihan Li,Yun Li,Penelope A. Lind,Xiaoxiao Liu,Leina Lu,Donald J. MacIntyre,Dean F. MacKinnon,Robert Maier,Wolfgang Maier,Jonathan Marchini,Hamdi Mbarek,Patrick J. McGrath,Peter McGuffin,Sarah E. Medland,Divya Mehta,Divya Mehta,Christel M. Middeldorp,Christel M. Middeldorp,Evelin Mihailov,Yuri Milaneschi,Lili Milani,Jonathan Mill,Francis M. Mondimore,Grant W. Montgomery,Sara Mostafavi,Niamh Mullins,Matthias Nauck,Bernard Ng,Michel G. Nivard,Dale R. Nyholt,Paul F. O'Reilly,Hogni Oskarsson,Michael John Owen,Jodie N. Painter,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Marianne Giørtz Pedersen,Marianne Giørtz Pedersen,Roseann E. Peterson,Erik Pettersson,Wouter J. Peyrot,Giorgio Pistis,Danielle Posthuma,Shaun Purcell,Jorge A. Quiroz,Per Qvist,Per Qvist,John P. Rice,Brien P. Riley,Margarita Rivera,Margarita Rivera,Saira Saeed Mirza,Richa Saxena,Richa Saxena,Robert A. Schoevers,Eva C. Schulte,Ling Shen,Jianxin Shi,Stanley I. Shyn,Engilbert Sigurdsson,Grant Sinnamon,Johannes H. Smit,Daniel J. Smith,Hreinn Stefansson,Stacy Steinberg,Craig A. Stockmeier,Fabian Streit,Jana Strohmaier,Katherine E. Tansey,Henning Teismann,Alexander Teumer,Wesley K. Thompson,Pippa A. Thomson,Thorgeir E. Thorgeirsson,Chao Tian,Matthew Traylor,Jens Treutlein,Vassily Trubetskoy,André G. Uitterlinden,Daniel Umbricht,Sandra Van der Auwera,Albert M. van Hemert,Alexander Viktorin,Peter M. Visscher,Yunpeng Wang,Yunpeng Wang,Yunpeng Wang,Bradley T. Webb,Shantel Weinsheimer,Shantel Weinsheimer,Jürgen Wellmann,Gonneke Willemsen,Stephanie H. Witt,Yang Wu,Hualin S. Xi,Jian Yang,Futao Zhang,Volker Arolt,Bernhard T. Baune,Klaus Berger,Dorret I. Boomsma,Sven Cichon,Udo Dannlowski,E. C.J. De Geus,J. Raymond DePaulo,Enrico Domenici,Katharina Domschke,Tõnu Esko,Tõnu Esko,Hans J. Grabe,Steven P. Hamilton,Caroline Hayward,Andrew C. Heath,David A. Hinds,Kenneth S. Kendler,Stefan Kloiber,Stefan Kloiber,Stefan Kloiber,Glyn Lewis,Qingqin S. Li,Susanne Lucae,Pamela F.A. Madden,Patrik K. E. Magnusson,Nicholas G. Martin,Andrew M. McIntosh,Andres Metspalu,Ole Mors,Ole Mors,Preben Bo Mortensen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Merete Nordentoft,Merete Nordentoft,Markus M. Nöthen,Michael Conlon O'Donovan,Sara A. Paciga,Nancy L. Pedersen,Brenda W.J.H. Penninx,Roy H. Perlis,David J. Porteous,James B. Potash,Martin Preisig,Marcella Rietschel,Catherine Schaefer,Thomas G. Schulze,Jordan W. Smoller,Jordan W. Smoller,Kari Stefansson,Kari Stefansson,Henning Tiemeier,Rudolf Uher,Henry Völzke,Myrna M. Weissman,Myrna M. Weissman,Thomas Werge,Thomas Werge,Thomas Werge,Ashley R. Winslow,Ashley R. Winslow,Cathryn M. Lewis,Douglas F. Levinson,Gerome Breen,Anders D. Børglum,Anders D. Børglum,Patrick F. Sullivan,Patrick F. Sullivan +262 more
TL;DR: A genome-wide association meta-analysis of individuals with clinically assessed or self-reported depression identifies 44 independent and significant loci and finds important relationships of genetic risk for major depression with educational attainment, body mass, and schizophrenia.
Journal ArticleDOI
Genome-wide association study identifies 30 loci associated with bipolar disorder
Eli A. Stahl,Eli A. Stahl,Gerome Breen,Andreas J. Forstner,Andrew McQuillin,Stephan Ripke,Stephan Ripke,Stephan Ripke,Vassily Trubetskoy,Manuel Mattheisen,Yunpeng Wang,Yunpeng Wang,Jonathan R. I. Coleman,Helena Gaspar,Christiaan de Leeuw,Stacy Steinberg,Jennifer M. Whitehead Pavlides,Maciej Trzaskowski,Enda M. Byrne,Tune H. Pers,Tune H. Pers,Peter Holmans,Alexander Richards,Liam Abbott,Esben Agerbo,Esben Agerbo,Huda Akil,Diego Albani,Ney Alliey-Rodriguez,Thomas Damm Als,Thomas Damm Als,Adebayo Anjorin,Verneri Antilla,Swapnil Awasthi,Judith A. Badner,Marie Bækvad-Hansen,Marie Bækvad-Hansen,Jack D. Barchas,Nicholas Bass,Michael Bauer,Richard A. Belliveau,Sarah E. Bergen,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Erlend Bøen,Marco P. Boks,James Boocock,Monika Budde,William E. Bunney,Margit Burmeister,Jonas Bybjerg-Grauholm,Jonas Bybjerg-Grauholm,William Byerley,Miquel Casas,Felecia Cerrato,Pablo Cervantes,Kimberly Chambert,Alexander W. Charney,Danfeng Chen,Claire Churchhouse,Claire Churchhouse,Toni-Kim Clarke,William Coryell,David Craig,Cristiana Cruceanu,Cristiana Cruceanu,David Curtis,David Curtis,Piotr M. Czerski,Anders M. Dale,Simone de Jong,Franziska Degenhardt,Jurgen Del-Favero,J. Raymond DePaulo,Srdjan Djurovic,Srdjan Djurovic,Amanda Dobbyn,Ashley Dumont,Torbjørn Elvsåshagen,Valentina Escott-Price,Chun Chieh Fan,Sascha B. Fischer,Sascha B. Fischer,Matthew Flickinger,Tatiana Foroud,Liz Forty,Josef Frank,Christine Fraser,Nelson B. Freimer,Louise Frisén,Katrin Gade,Katrin Gade,Diane Gage,Julie Garnham,Claudia Giambartolomei,Marianne Giørtz Pedersen,Marianne Giørtz Pedersen,Jaqueline Goldstein,Scott D. Gordon,Katherine Gordon-Smith,Elaine K. Green,Melissa J. Green,Melissa J. Green,Tiffany A. Greenwood,Jakob Grove,Weihua Guan,Jose Guzman-Parra,Marian L. Hamshere,Martin Hautzinger,Urs Heilbronner,Stefan Herms,Stefan Herms,Stefan Herms,Maria Hipolito,Per Hoffmann,Per Hoffmann,Per Hoffmann,Dominic Holland,Laura M. Huckins,Stéphane Jamain,Stéphane Jamain,Jessica S. Johnson,Anders Juréus,Radhika Kandaswamy,Robert Karlsson,James L. Kennedy,Sarah Kittel-Schneider,James A. Knowles,Manolis Kogevinas,Anna C. Koller,Ralph W. Kupka,Catharina Lavebratt,Jacob Lawrence,William Lawson,Markus Leber,Phil Lee,Phil Lee,Shawn Levy,Jun Li,Chunyu Liu,Susanne Lucae,Anna Maaser,Donald J. MacIntyre,Pamela B. Mahon,Pamela B. Mahon,Wolfgang Maier,Lina Martinsson,Steve McCarroll,Steve McCarroll,Peter McGuffin,Melvin G. McInnis,James McKay,Helena Medeiros,Sarah E. Medland,Fan Meng,Fan Meng,Lili Milani,Grant W. Montgomery,Derek W. Morris,Derek W. Morris,Thomas W. Mühleisen,Thomas W. Mühleisen,Niamh Mullins,Hoang T. Nguyen,Caroline M. Nievergelt,Caroline M. Nievergelt,Annelie Nordin Adolfsson,Evaristus A. Nwulia,Claire O'Donovan,Loes M. Olde Loohuis,Anil P.S. Ori,Lilijana Oruc,Urban Ösby,Roy H. Perlis,Amy Perry,Andrea Pfennig,James B. Potash,Shaun Purcell,Shaun Purcell,Eline J. Regeer,Andreas Reif,Céline S. Reinbold,Céline S. Reinbold,John P. Rice,Fabio Rivas,Margarita Rivera,Margarita Rivera,Panos Roussos,Douglas M. Ruderfer,Euijung Ryu,Cristina Sánchez-Mora,Cristina Sánchez-Mora,Alan F. Schatzberg,William A. Scheftner,Nicholas J. Schork,Cynthia Shannon Weickert,Cynthia Shannon Weickert,Tatyana Shehktman,Paul D. Shilling,Engilbert Sigurdsson,Claire Slaney,Olav B. Smeland,Olav B. Smeland,Janet L. Sobell,Christine Søholm Hansen,Christine Søholm Hansen,Anne T. Spijker,David St Clair,Michael Steffens,John Strauss,John Strauss,Fabian Streit,Jana Strohmaier,Szabolcs Szelinger,Robert C. Thompson,Thorgeir E. Thorgeirsson,Jens Treutlein,Helmut Vedder,Weiqing Wang,Stanley J. Watson,Thomas W. Weickert,Thomas W. Weickert,Stephanie H. Witt,Simon Xi,Wei Xu,Wei Xu,Allan H. Young,Peter P. Zandi,Peng Zhang,Sebastian Zöllner,Rolf Adolfsson,Ingrid Agartz,Ingrid Agartz,Martin Alda,Martin Alda,Lena Backlund,Bernhard T. Baune,Bernhard T. Baune,Frank Bellivier,Wade H. Berrettini,Joanna M. Biernacka,Douglas Blackwood,Michael Boehnke,Anders D. Børglum,Anders D. Børglum,Aiden Corvin,Nicholas John Craddock,Mark J. Daly,Mark J. Daly,Udo Dannlowski,Tõnu Esko,Bruno Etain,Mark A. Frye,Janice M. Fullerton,Janice M. Fullerton,Elliot S. Gershon,Michael Gill,Fernando S. Goes,Maria Grigoroiu-Serbanescu,Joanna Hauser,David M. Hougaard,David M. Hougaard,Christina M. Hultman,Ian Jones,Lisa Jones,René S. Kahn,George Kirov,Mikael Landén,Mikael Landén,Marion Leboyer,Marion Leboyer,Cathryn M. Lewis,Qingqin S. Li,Jolanta Lissowska,Nicholas G. Martin,Nicholas G. Martin,Fermín Mayoral,Susan L. McElroy,Andrew M. McIntosh,Francis J. McMahon,Ingrid Melle,Andres Metspalu,Philip B. Mitchell,Gunnar Morken,Ole Mors,Ole Mors,Preben Bo Mortensen,Preben Bo Mortensen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Richard M. Myers,Benjamin M. Neale,Benjamin M. Neale,Vishwajit L. Nimgaonkar,Merete Nordentoft,Merete Nordentoft,Markus M. Nöthen,Michael Conlon O'Donovan,Ketil J. Oedegaard,Michael John Owen,Sara A. Paciga,Carlos N. Pato,Michele T. Pato,Danielle Posthuma,Josep Antoni Ramos-Quiroga,Marta Ribasés,Marta Ribasés,Marcella Rietschel,Guy A. Rouleau,Guy A. Rouleau,Martin Schalling,Peter R. Schofield,Peter R. Schofield,Thomas G. Schulze,Alessandro Serretti,Jordan W. Smoller,Jordan W. Smoller,Hreinn Stefansson,Kari Stefansson,Kari Stefansson,Eystein Stordal,Patrick F. Sullivan,Patrick F. Sullivan,Gustavo Turecki,Arne E. Vaaler,Eduard Vieta,John B. Vincent,Thomas Werge,Thomas Werge,Thomas Werge,John I. Nurnberger,Naomi R. Wray,Arianna Di Florio,Arianna Di Florio,Howard J. Edenberg,Sven Cichon,Roel A. Ophoff,Laura J. Scott,Ole A. Andreassen,Ole A. Andreassen,John R. Kelsoe,Pamela Sklar,Pamela Sklar +342 more
TL;DR: Genome-wide analysis identifies 30 loci associated with bipolar disorder, allowing for comparisons of shared genes and pathways with other psychiatric disorders, including schizophrenia and depression.
Journal ArticleDOI
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Douglas M. Ruderfer,Stephan Ripke,Stephan Ripke,Stephan Ripke,Andrew McQuillin,James Boocock,Eli A. Stahl,Jennifer M. Whitehead Pavlides,Niamh Mullins,Alexander W. Charney,Anil P.S. Ori,Loes M. Olde Loohuis,Enrico Domenici,Arianna Di Florio,Sergi Papiol,Janos Kalman,Vassily Trubetskoy,Rolf Adolfsson,Ingrid Agartz,Ingrid Agartz,Esben Agerbo,Esben Agerbo,Huda Akil,Diego Albani,Margot Albus,Martin Alda,Martin Alda,Madeline Alexander,Ney Alliey-Rodriguez,Thomas Damm Als,Thomas Damm Als,Farooq Amin,Farooq Amin,Adebayo Anjorin,Maria Arranz,Maria Arranz,Swapnil Awasthi,Silviu Alin Bacanu,Judith A. Badner,Marie Bækvad-Hansen,Steven C. Bakker,Gavin Band,Jack D. Barchas,Inês Barroso,Nicholas Bass,Michael Bauer,Bernhard T. Baune,Martin Begemann,Céline Bellenguez,Richard A. Belliveau,Frank Bellivier,Stephan Bender,Judit Bene,Sarah E. Bergen,Sarah E. Bergen,Wade H. Berrettini,Elizabeth Bevilacqua,Joanna M. Biernacka,Tim B. Bigdeli,Donald W. Black,Hannah Blackburn,Jenefer M. Blackwell,Jenefer M. Blackwell,Douglas Blackwood,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Michael Boehnke,Marco P. Boks,Anders D. Børglum,Anders D. Børglum,Elvira Bramon,Elvira Bramon,Gerome Breen,Gerome Breen,Matthew A. Brown,Richard Bruggeman,Nancy G. Buccola,Randy L. Buckner,Monika Budde,Brendan Bulik-Sullivan,Brendan Bulik-Sullivan,Suzannah Bumpstead,William E. Bunney,Margit Burmeister,Joseph D. Buxbaum,Jonas Bybjerg-Grauholm,William Byerley,Wiepke Cahn,Guiqing Cai,Murray J. Cairns,Dominique Campion,Rita M. Cantor,Vaughan J. Carr,Noa Carrera,Juan P. Casas,Juan P. Casas,Miquel Casas,Miquel Casas,Stanley V. Catts,Pablo Cervantes,Kimberley D. Chambert,Raymond C.K. Chan,Eric Y.H. Chen,Ronald Y.L. Chen,Wei Cheng,Eric F.C. Cheung,Siow Ann Chong,Toni-Kim Clarke,C. Robert Cloninger,David Cohen,Nadine Cohen,Jonathan R. I. Coleman,Jonathan R. I. Coleman,David A. Collier,David A. Collier,Paul Cormican,William Coryell,Nicholas John Craddock,David Craig,Benedicto Crespo-Facorro,James J. Crowley,Cristiana Cruceanu,David Curtis,David Curtis,Piotr M. Czerski,Anders M. Dale,Mark J. Daly,Mark J. Daly,Udo Dannlowski,Ariel Darvasi,Michael Davidson,Kenneth L. Davis,Christiaan de Leeuw,Franziska Degenhardt,Jurgen Del Favero,Lynn E. DeLisi,Panos Deloukas,Ditte Demontis,Ditte Demontis,J. Raymond DePaulo,Marta Di Forti,Dimitris Dikeos,Timothy G. Dinan,Srdjan Djurovic,Amanda Dobbyn,Peter Donnelly,Gary Donohoe,Gary Donohoe,Elodie Drapeau,Serge Dronov,Jubao Duan,Jubao Duan,Frank Dudbridge,Audrey Duncanson,Howard J. Edenberg,Sarah Edkins,Hannelore Ehrenreich,Peter Eichhammer,Torbjørn Elvsåshagen,Johan G. Eriksson,Valentina Escott-Price,Tõnu Esko,Tõnu Esko,Tõnu Esko,Laurent Essioux,Bruno Etain,Chun Chieh Fan,Kai-How Farh,Martilias S. Farrell,Matthew Flickinger,Tatiana Foroud,Liz Forty,Josef Frank,Lude Franke,Christine Fraser,Robert Freedman,Colin Freeman,Nelson B. Freimer,Joseph I. Friedman,Menachem Fromer,Menachem Fromer,Menachem Fromer,Mark A. Frye,Janice M. Fullerton,Janice M. Fullerton,Katrin Gade,Katrin Gade,Julie Garnham,Helena Gaspar,Pablo V. Gejman,Pablo V. Gejman,Giulio Genovese,Lyudmila Georgieva,Claudia Giambartolomei,Eleni Giannoulatou,Ina Giegling,Ina Giegling,Michael Gill,Matthew Gillman,Marianne Giørtz Pedersen,Paola Giusti-Rodríguez,Stephanie Godard,Fernando S. Goes,Jacqueline I. Goldstein,Jacqueline I. Goldstein,Srihari Gopal,Scott D. Gordon,Katherine Gordon-Smith,Jacob Gratten,Emma Gray,Elaine K. Green,Melissa J. Green,Tiffany A. Greenwood,Maria Grigoroiu-Serbanescu,Jakob Grove,Jakob Grove,Weihua Guan,Hugh Gurling,Jose Guzman Parra,Rhian Gwilliam,Lieuwe de Haan,Jeremy Hall,Mei-Hua Hall,Christian Hammer,Naomi Hammond,Marian L. Hamshere,Mark Hansen,Thomas Hansen,Vahram Haroutunian,Vahram Haroutunian,Annette M. Hartmann,Joanna Hauser,Martin Hautzinger,Urs Heilbronner,Garrett Hellenthal,Frans Henskens,Stefan Herms,Stefan Herms,Maria Hipolito,Joel N. Hirschhorn,Joel N. Hirschhorn,Per Hoffmann,Per Hoffmann,Mads V. Hollegaard,David M. Hougaard,Hailiang Huang,Hailiang Huang,Laura M. Huckins,Christina M. Hultman,Sarah E. Hunt,Masashi Ikeda,Nakao Iwata,Conrad Iyegbe,Assen Jablensky,Stéphane Jamain,Janusz Jankowski,Alagurevathi Jayakumar,Inge Joa,Ian Jones,Lisa Jones,Erik G. Jönsson,Erik G. Jönsson,Antonio Julià,Anders Juréus,Anna K. Kähler,René S. Kahn,René S. Kahn,Luba Kalaydjieva,Radhika Kandaswamy,Sena Karachanak-Yankova,Juha Karjalainen,Robert Karlsson,David J. Kavanagh,Matthew C. Keller,Brian Kelly,John R. Kelsoe,James L. Kennedy,Andrey Khrunin,Yunjung Kim,George Kirov,Sarah Kittel-Schneider,Janis Klovins,Jo Knight,Sarah Knott,James A. Knowles,James A. Knowles,Manolis Kogevinas,Bettina Konte,Eugenia Kravariti,Vaidutis Kučinskas,Zita Ausrele Kucinskiene,Ralph Kupka,Ralph Kupka,Hana Kuzelova-Ptackova,Mikael Landén,Mikael Landén,Cordelia Langford,Claudine Laurent,Claudine Laurent,Jacob Lawrence,Stephen M. Lawrie,William Lawson,Markus Leber,Marion Leboyer,Marion Leboyer,Phil Lee,Phil Lee,Jimmy Lee Chee Keong,Sophie E. Legge,Todd Lencz,Todd Lencz,Bernard Lerer,Douglas F. Levinson,Shawn Levy,Cathryn M. Lewis,Cathryn M. Lewis,Jun Li,Miaoxin Li,Qingqin S. Li,Tao Li,Kung-Yee Liang,Jennifer Liddle,Jeffrey A. Lieberman,Svetlana A. Limborska,Kuang Lin,Don H. Linszen,Jolanta Lissowska,Chunyu Liu,Jianjun Liu,Jianjun Liu,Jouko Lönnqvist,Carmel M. Loughland,Jan Lubinski,Susanne Lucae,Milan Macek,Donald J. MacIntyre,Donald J. MacIntyre,Patrik K. E. Magnusson,Brion S. Maher,Pamela B. Mahon,Pamela B. Mahon,Wolfgang Maier,Anil K. Malhotra,Anil K. Malhotra,J. Mallet,Ulrik Fredrik Malt,Hugh S. Markus,Sara Marsal,Nicholas G. Martin,Nicholas G. Martin,Ignacio Mata,Christopher G. Mathew,Manuel Mattheisen,Morten Mattingsdal,Fermín Mayoral,Owen T. McCann,Robert W. McCarley,Steven A. McCarroll,Steven A. McCarroll,Mark I. McCarthy,Colm McDonald,Susan L. McElroy,Peter McGuffin,Melvin G. McInnis,Andrew M. McIntosh,James McKay,Francis J. McMahon,Helena Medeiros,Sarah E. Medland,Sandra Meier,Carin J. Meijer,Béla Melegh,Ingrid Melle,Fan Meng,Raquelle I. Mesholam-Gately,Andres Metspalu,Patricia T. Michie,Lili Milani,Vihra Milanova,Philip B. Mitchell,Younes Mokrab,Grant W. Montgomery,Jennifer L. Moran,Gunnar Morken,Derek W. Morris,Derek W. Morris,Ole Mors,Ole Mors,Preben Bo Mortensen,Preben Bo Mortensen,Bryan J. Mowry,Thomas W. Mühleisen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Kieran C. Murphy,Robin M. Murray,Richard M. Myers,Inez Myin-Germeys,Benjamin M. Neale,Benjamin M. Neale,Mari Nelis,Igor Nenadic,Deborah A. Nertney,Gerald Nestadt,Kristin K. Nicodemus,Caroline M. Nievergelt,Caroline M. Nievergelt,Liene Nikitina-Zake,Vishwajit L. Nimgaonkar,Laura Nisenbaum,Merete Nordentoft,Annelie Nordin,Markus M. Nöthen,Evaristus A. Nwulia,Eadbhard O'Callaghan,Claire O'Donovan,Colm O'Dushlaine,F. Anthony O'Neill,Ketil J. Oedegaard,Sang-Yun Oh,Ann Olincy,Line Olsen,Lilijana Oruc,Jim van Os,Jim van Os,Michael John Owen,Sara A. Paciga,Colin N. A. Palmer,Aarno Palotie,Aarno Palotie,Aarno Palotie,Christos Pantelis,George N. Papadimitriou,Elena Parkhomenko,Carlos N. Pato,Michele T. Pato,Tiina Paunio,Tiina Paunio,Richard G. Pearson,Diana O. Perkins,Roy H. Perlis,Amy Perry,Tune H. Pers,Tune H. Pers,Tune H. Pers,Tracey L. Petryshen,Tracey L. Petryshen,Andrea Pfennig,Marco Picchioni,Olli Pietiläinen,Olli Pietiläinen,Jonathan Pimm,Matti Pirinen,Robert Plomin,Andrew Pocklington,Danielle Posthuma,Danielle Posthuma,James B. Potash,Simon C. Potter,John Powell,Alkes L. Price,Alkes L. Price,Ann E. Pulver,Shaun Purcell,Shaun Purcell,Digby Quested,Josep Antoni Ramos-Quiroga,Josep Antoni Ramos-Quiroga,Henrik B. Rasmussen,Anna Rautanen,Radhi Ravindrarajah,Eline J. Regeer,Abraham Reichenberg,Andreas Reif,Mark Reimers,Marta Ribasés,Marta Ribasés,John P. Rice,Alexander Richards,Michelle Ricketts,Brien P. Riley,Fabio Rivas,Margarita Rivera,Margarita Rivera,Joshua L. Roffman,Guy A. Rouleau,Panos Roussos,Dan Rujescu,Dan Rujescu,Veikko Salomaa,Cristina Sánchez-Mora,Cristina Sánchez-Mora,Alan R. Sanders,Alan R. Sanders,Stephen Sawcer,Ulrich Schall,Alan F. Schatzberg,William A. Scheftner,Peter R. Schofield,Peter R. Schofield,Nicholas J. Schork,Sibylle G. Schwab,Edward M. Scolnick,Laura J. Scott,Rodney J. Scott,Larry J. Seidman,Alessandro Serretti,Pak C. Sham,Cynthia Shannon Weickert,Cynthia Shannon Weickert,Tatyana Shehktman,Jianxin Shi,Paul D. Shilling,Engilbert Sigurdsson,Jeremy M. Silverman,Jeremy M. Silverman,Kang Sim,Claire Slaney,Petr Slominsky,Olav B. Smeland,Olav B. Smeland,Jordan W. Smoller,Jordan W. Smoller,Hon-Cheong So,Janet L. Sobell,Erik Söderman,Christine Søholm Hansen,Chris C. A. Spencer,Anne T. Spijker,David St Clair,Hreinn Stefansson,Kari Stefansson,Kari Stefansson,Stacy Steinberg,Elisabeth Stögmann,Eystein Stordal,Amy Strange,Richard E. Straub,John Strauss,Fabian Streit,Eric Strengman,Jana Strohmaier,T. Scott Stroup,Zhan Su,Mythily Subramaniam,Jaana Suvisaari,Dragan M. Svrakic,Jin P. Szatkiewicz,Szabolcs Szelinger,Avazeh Tashakkori-Ghanbaria,Srinivas Thirumalai,Robert C. Thompson,Thorgeir E. Thorgeirsson,Draga Toncheva,Paul A. Tooney,Sarah Tosato,Timothea Toulopoulou,Richard C. Trembath,Jens Treutlein,Gustavo Turecki,Arne E. Vaaler,Helmut Vedder,Eduard Vieta,John B. Vincent,Peter M. Visscher,Ananth C. Viswanathan,Ananth C. Viswanathan,Damjan Vukcevic,John L. Waddington,Matthew Waller,Dermot Walsh,Muriel Walshe,James T.R. Walters,Dai Wang,Qiang Wang,Weiqing Wang,Yunpeng Wang,Stanley J. Watson,Bradley T. Webb,Thomas W. Weickert,Thomas W. Weickert,Daniel R. Weinberger,Matthias Weisbrod,Mark Weiser,Thomas Werge,Thomas Werge,Paul A. Weston,Pamela Whittaker,Sara Widaa,Durk Wiersma,Dieter B. Wildenauer,Nigel Williams,Stephanie Williams,Stephanie H. Witt,Aaron R. Wolen,Emily H. M. Wong,Nicholas W. Wood,Brandon Wormley,Jing Qin Wu,Simon Xi,Wei Xu,Wei Xu,Allan H. Young,Clement C. Zai,Peter P. Zandi,Peng Zhang,Xuebin Zheng,Fritz Zimprich,Sebastian Zöllner,Aiden Corvin,Ayman H. Fanous,Sven Cichon,Sven Cichon,Marcella Rietschel,Elliot S. Gershon,Thomas G. Schulze,Alfredo B. Cuellar-Barboza,Alfredo B. Cuellar-Barboza,Andreas J. Forstner,Andreas J. Forstner,Peter Holmans,John I. Nurnberger,Ole A. Andreassen,S. Hong Lee,Michael Conlon O'Donovan,Patrick F. Sullivan,Patrick F. Sullivan,Roel A. Ophoff,Roel A. Ophoff,Naomi R. Wray,Pamela Sklar,Kenneth S. Kendler +631 more
TL;DR: For the first time, specific loci that distinguish between BD and SCZ are discovered and polygenic components underlying multiple symptom dimensions are identified that point to the utility of genetics to inform symptomology and potential treatment.
Journal ArticleDOI
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Vassily Trubetskoy,Antonio F. Pardiñas,Ting Qi,Georgia Panagiotaropoulou,Swapnil Awasthi,Tim B. Bigdeli,Julien Bryois,Chia-Yen Chen,Charlotte Dennison,Lynsey S. Hall,Max Lam,Kyoko Watanabe,Oleksandr Frei,Tian Ge,Janet C Harwood,Frank Koopmans,Sigurdur Magnusson,Alexander Richards,Julia Sidorenko,Yang Wu,Jian Zeng,Jakob Grove,Minsoo Kim,Zhiqiang Li,Georgios Voloudakis,Wen Jie Zhang,Mark Adams,Ingrid Agartz,Elizabeth G. Atkinson,Esben Agerbo,Mariam M. Al Eissa,Margot Albus,Madeline Alexander,Behrooz Z. Alizadeh,Köksal Alptekin,Thomas Damm Als,Farooq Amin,Volker Arolt,Manuel Arrojo,Lavinia Athanasiu,M. Helena Azevedo,Silviu Alin Bacanu,Nicholas Bass,Martin Begemann,Richard A. Belliveau,Judit Bene,Beben Benyamin,Sarah E. Bergen,Giuseppe Blasi,Julio Bobes,Stefano Bonassi,Alice Braun,Rodrigo A. Bressan,Evelyn J. Bromet,Richard Bruggeman,Peter J. Buckley,Randy L. Buckner,Jonas Bybjerg-Grauholm,Wiepke Cahn,Murray J. Cairns,Monica E. Calkins,Vaughan J. Carr,David J. Castle,Stanley V. Catts,Kimberly Chambert,Raymond C.K. Chan,Boris Chaumette,Wei Cheng,Eric F.C. Cheung,Siow Ann Chong,David Cohen,Angèle Consoli,Quirino Cordeiro,Javier Costas,Charles Curtis,Michael H. Davidson,Kenneth L. Davis,Lieuwe de Haan,Franziska Degenhardt,Lynn E. DeLisi,Ditte Demontis,Faith Dickerson,Dimitris Dikeos,Timothy G. Dinan,Srdjan Djurovic,Jubao Duan,Giuseppe Ducci,Frank Dudbridge,Johan G. Eriksson,Lourdes Fañanás,Stephen V. Faraone,Alessia Fiorentino,Andreas J. Forstner,Josef Frank,Nelson B. Freimer,Menachem Fromer,Alessandra Frustaci,Ary Gadelha,Giulio Genovese,Elliot S. Gershon,Marianna Giannitelli,Ina Giegling,Paola Giusti-Rodríguez,Stephanie Godard,Jackie Goldstein,Javier González Peñas,Ana González-Pinto,Srihari Gopal,Jacob Gratten,Michael F. Green,Tiffany A. Greenwood,Olivier Guillin,Sinan Gülöksüz,Raquel E. Gur,Ruben C. Gur,Blanca Gutiérrez,Eric Hahn,Hakon Hakonarson,Vahram Haroutunian,T. Hartmann,Carol Harvey,Caroline Hayward,Frans Henskens,Stefan Herms,Per Hoffmann,Daniel P. Howrigan,Masashi Ikeda,Conrad Iyegbe,Inge Joa,Antonio Julià,Anna K. Kähler,Tony Kam-Thong,Yoichiro Kamatani,Sena Karachanak-Yankova,Oussama Kebir,Matthew C. Keller,Brian Kelly,Andrey Khrunin,Sung-Wan Kim,Janis Klovins,N. V. Kondratiev,Bettina Konte,Julia Kraft,Michiaki Kubo,Vaidutis Kučinskas,Zita Ausrele Kucinskiene,Agung A.A.A Kusumawardhani,Hana Kuzelova-Ptackova,Stefano Landi,Laura C. Lazzeroni,Phil Lee,Sophie E. Legge,Douglas S. Lehrer,Rebekka Lencer,Bernard Lerer,Miaoxin Li,Jeffrey A. Lieberman,Gregory A. Light,Svetlana A. Limborska,Chih-Min Liu,Jouko Lönnqvist,Carmel M. Loughland,Jan Lubinski,Jurjen J. Luykx,Amy Lynham,Milan Macek,Andrew Mackinnon,Patrik K. E. Magnusson,Brion S. Maher,Wolfgang Mader,Dolores Malaspina,Jacques Mallet,Stephen R. Marder,Sara Marsal,Alicia R. Martin,Lourdes Martorell,Manuel Mattheisen,Robert W. McCarley,Colm McDonald,John J. McGrath,Helena Medeiros,Sandra Meier,Béla Melegh,Ingrid Melle,Raquelle I. Mesholam-Gately,Andres Metspalu,Patricia T. Michie,Lili Milani,Vihra Milanova,Marina Mitjans,Espen Molden,Esther Molina,María Dolores Moltó,Valeria Mondelli,Carmen Moreno,Christopher P. Morley,Gerard Muntané,Kieran C. Murphy,Inez Myin-Germeys,Igor Nenadic,Gerald Nestadt,Liene Nikitina-Zake,Cristiano Noto,Keith H. Nuechterlein,Niamh L. O'Brien,F. Anthony O'Neill,Sang Oh,Ann Olincy,Vanessa Kiyomi Ota,Christos Pantelis,George N. Papadimitriou,Mara Parellada,Tiina Paunio,Renata Pellegrino,Sathish Periyasamy,Diana O. Perkins,Bruno Pfuhlmann,Olli Pietiläinen,Jonathan Pimm,David J. Porteous,John Powell,Diego Quattrone,Digby Quested,Allen D. Radant,Antonio Rampino,Mark Hyman Rapaport,Anna Rautanen,Abraham Reichenberg,Cheryl A. Roe,Joshua L. Roffman,Julian Roth,Matthias Rothmund,Bart P. F. Rutten,Safaa Saker-Delye,Veikko Salomaa,Julio Sanjuán,Marcos L. Santoro,Adam Savitz,Ulrich Schall,Rodney J. Scott,Larry J. Seidman,Sally I. Sharp,Jianxin Shi,Larry J. Siever,Engilbert Sigurdsson,Kang Sim,Nora Skarabis,Petr Slominsky,Hon-Cheong So,Janet L. Sobell,Erik Söderman,Helen J. Stain,Nils Eiel Steen,Agnes A. Steixner-Kumar,Elisabeth Stögmann,William S. Stone,Richard E. Straub,Fabian Streit,Eric Strengman,T. Scott Stroup,Mythily Subramaniam,Catherine A. Sugar,Jaana Suvisaari,Dragan M. Svrakic,Neal R. Swerdlow,Jin P. Szatkiewicz,Thi Minh Tam Ta,Atsushi Takahashi,Chikashi Terao,Florence Thibaut,Draga Toncheva,Paul A. Tooney,Silvia Torretta,Sarah Tosato,G.B. Tura,Bruce I. Turetsky,Alp Üçok,Arne E. Vaaler,Therese van Amelsvoort,Ruud van Winkel,Juha Veijola,John L. Waddington,Henrik Walter,Anna Waterreus,Bradley T. Webb,Mark Weiser,Nigel Williams,Stephanie H. Witt,Brandon Wormley,Jing Qin Wu,Zhida Xu,R.T Yolken,Clement C. Zai,Wei Zhou,Feng Zhu,Fritz Zimprich,E. Cem Atbasoglu,Muhammad Ayub,Christian Benner,Alessandro Bertolini,Donald W. Black,Nicholas John Bray,Gerome Breen,Nancy G. Buccola,William Byerley,Wei J. Chen,C. Robert Cloninger,Benedicto Crespo-Facorro,Gary Donohoe,Robert Freedman,Cherrie Galletly,Michael J. Gandal,Massimo Gennarelli,David M. Hougaard,Hai-Gwo Hwu,Assen Jablensky,Steven A. McCarroll,Jennifer L. Moran,Ole Mors,Preben Bo Mortensen,Bertram Müller-Myhsok,Amanda L. Neil,Merete Nordentoft,Michele T. Pato,Tracey L. Petryshen,Matti Pirinen,Ann E. Pulver,Thomas G. Schulze,Jeremy M. Silverman,Jordan W. Smoller,Eli A. Stahl,Debby W. Tsuang,Elisabet Vilella,Shi‐Heng Wang,Shuhua Xu,Rolf Adolfsson,Celso Arango,Bernhard T. Baune,Sintia Iole Belangero,Anders D. Børglum,David L. Braff,Elvira Bramon,Joseph D. Buxbaum,Dominique Campion,Jorge A. Cervilla,Sven Cichon,David A. Collier,Aiden Corvin,David Curtis,Marta Di Forti,Enrico Domenici,Hannelore Ehrenreich,Valentina Escott-Price,Tõnu Esko,Ayman H. Fanous,A. E. Gareeva,Micha Gawlik,Pablo V. Gejman,Michael Gill,Stephen J. Glatt,Vera Golimbet,Kyung Sue Hong,Christina M. Hultman,Steven E. Hyman,Nakao Iwata,Erik G. Jönsson,René S. Kahn,James L. Kennedy,Elza Khusnutdinova,George Kirov,James A. Knowles,Marie-Odile Krebs,Claudine Laurent-Levinson,Jimmy Lee,Todd Lencz,Douglas F. Levinson,Qingqin S. Li,Jianjun Liu,Anil K. Malhotra,Dheeraj Malhotra,Andrew M. McIntosh,Andrew McQuillin,Paulo Rossi Menezes,Vera A. Morgan,Derek W. Morris,Bryan J. Mowry,Robin M. Murray,Vishwajit L. Nimgaonkar,Markus M. Nöthen,Roel A. Ophoff,Sara A. Paciga,Aarno Palotie,Carlos N. Pato,Shengying Qin,Marcella Rietschel,Brien P. Riley,Margarita Rivera,Dan Rujescu,Meram Can Saka,Alan R. Sanders,Sibylle G. Schwab,Alessandro Serretti,Pak C. Sham,Yongyong Shi,David St Clair,Hreinn Stefansson,Kari Stefansson,Ming T. Tsuang,Jim van Os,Marquis P. Vawter,Daniel R. Weinberger,Thomas Werge,Dieter B. Wildenauer,Xin-ming Yu,Weihua Yue,Peter Holmans,Andrew Pocklington,Panos Roussos,Evangelos Vassos,Matthijs Verhage,Peter M. Visscher,Danielle Posthuma,Ole A. Andreassen,Kenneth S. Kendler,Michael John Owen,Naomi R. Wray,Mark J. Daly,Hailiang Huang,Benjamin M. Neale,Patrick F. Sullivan,Stephan Ripke,James T.R. Walters,Michael Conlon O'Donovan +432 more
TL;DR: In this article , a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control individuals was conducted, and the authors reported common variant associations at 287 distinct genomic loci.
Journal ArticleDOI
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Niamh Mullins,Andreas J. Forstner,Andreas J. Forstner,Andreas J. Forstner,Kevin S. O’Connell,Kevin S. O’Connell,Brandon J. Coombes,Jonathan R. I. Coleman,Zhen Qiao,Thomas Damm Als,Thomas Damm Als,Tim B. Bigdeli,Tim B. Bigdeli,Sigrid Børte,Sigrid Børte,Sigrid Børte,Julien Bryois,Alexander W. Charney,Ole Kristian Drange,Michael J. Gandal,Saskia P. Hagenaars,Masashi Ikeda,Nolan Kamitaki,Nolan Kamitaki,Minsoo Kim,Kristi Krebs,Georgia Panagiotaropoulou,Brian M. Schilder,Laura G. Sloofman,Stacy Steinberg,Vassily Trubetskoy,Bendik S. Winsvold,Bendik S. Winsvold,Hong-Hee Won,Liliya Abramova,Kristina Adorjan,Esben Agerbo,Esben Agerbo,Mariam M. Al Eissa,Diego Albani,Ney Alliey-Rodriguez,Ney Alliey-Rodriguez,Adebayo Anjorin,Verneri Antilla,Anastasia Antoniou,Swapnil Awasthi,Ji Hyun Baek,Marie Bækvad-Hansen,Marie Bækvad-Hansen,Nicholas Bass,Michael Bauer,Eva C. Beins,Sarah E. Bergen,Armin Birner,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Erlend Bøen,Marco P. Boks,Rosa Bosch,Murielle Brum,Ben Michael Brumpton,Nathalie Brunkhorst-Kanaan,Monika Budde,Jonas Bybjerg-Grauholm,Jonas Bybjerg-Grauholm,William Byerley,Murray J. Cairns,Miquel Casas,Pablo Cervantes,Toni-Kim Clarke,Cristiana Cruceanu,Cristiana Cruceanu,Alfredo B. Cuellar-Barboza,Alfredo B. Cuellar-Barboza,Julie M. Cunningham,David Curtis,David Curtis,Piotr M. Czerski,Anders M. Dale,Nina Dalkner,Friederike Sophie David,Franziska Degenhardt,Franziska Degenhardt,Srdjan Djurovic,Srdjan Djurovic,Amanda Dobbyn,Athanassios Douzenis,Torbjørn Elvsåshagen,Torbjørn Elvsåshagen,Valentina Escott-Price,I. Nicol Ferrier,Alessia Fiorentino,Tatiana Foroud,Liz Forty,Josef Frank,Oleksandr Frei,Oleksandr Frei,Nelson B. Freimer,Nelson B. Freimer,Louise Frisén,Katrin Gade,Katrin Gade,Julie Garnham,Joel Gelernter,Joel Gelernter,Marianne Giørtz Pedersen,Marianne Giørtz Pedersen,Ian R. Gizer,Scott D. Gordon,Katherine Gordon-Smith,Tiffany A. Greenwood,Jakob Grove,Jose Guzman-Parra,Kyooseob Ha,Magnús Haraldsson,Martin Hautzinger,Urs Heilbronner,Dennis Hellgren,Stefan Herms,Stefan Herms,Stefan Herms,Per Hoffmann,Per Hoffmann,Per Hoffmann,Peter Holmans,Laura M. Huckins,Stéphane Jamain,Stéphane Jamain,Jessica S. Johnson,Janos Kalman,Yoichiro Kamatani,James L. Kennedy,Sarah Kittel-Schneider,James A. Knowles,Manolis Kogevinas,Maria Koromina,Thorsten M. Kranz,Henry R. Kranzler,Michiaki Kubo,Ralph W. Kupka,Steven A. Kushner,Catharina Lavebratt,Catharina Lavebratt,Jacob Lawrence,Markus Leber,Heon Jeong Lee,Phil Lee,Shawn Levy,Catrin Lewis,Calwing Liao,Calwing Liao,Susanne Lucae,Martin Lundberg,Martin Lundberg,Donald J. MacIntyre,Sigurdur H. Magnusson,Wolfgang Maier,Adam X. Maihofer,Dolores Malaspina,Eirini Maratou,Lina Martinsson,Manuel Mattheisen,Steven A. McCarroll,Steven A. McCarroll,Nathaniel W. McGregor,Peter McGuffin,James McKay,Helena Medeiros,Sarah E. Medland,Vincent Millischer,Vincent Millischer,Grant W. Montgomery,Jennifer L. Moran,Jennifer L. Moran,Derek W. Morris,Thomas W. Mühleisen,Thomas W. Mühleisen,Niamh L. O'Brien,Claire O'Donovan,Loes M. Olde Loohuis,Loes M. Olde Loohuis,Lilijana Oruc,Sergi Papiol,Antonio F. Pardiñas,Amy Perry,Andrea Pfennig,Evgenia Porichi,James B. Potash,Digby Quested,Digby Quested,Towfique Raj,Mark Hyman Rapaport,J. Raymond DePaulo,Eline J. Regeer,John P. Rice,Fabio Rivas,Margarita Rivera,Julian Roth,Panos Roussos,Douglas M. Ruderfer,Cristina Sánchez-Mora,Eva C. Schulte,Fanny Senner,Sally I. Sharp,Paul D. Shilling,Engilbert Sigurdsson,Lea Sirignano,Claire Slaney,Olav B. Smeland,Olav B. Smeland,Daniel J. Smith,Janet L. Sobell,Christine Søholm Hansen,Christine Søholm Hansen,María Soler Artigas,Anne T. Spijker,Dan J. Stein,John Strauss,Beata Świątkowska,Chikashi Terao,Thorgeir E. Thorgeirsson,Claudio Toma,Claudio Toma,Claudio Toma,Paul A. Tooney,Evangelia-Eirini Tsermpini,Marquis P. Vawter,Helmut Vedder,James T.R. Walters,Stephanie H. Witt,Simon Xi,Wei Xu,Jessica Yang,Allan H. Young,Allan H. Young,Hannah Young,Peter P. Zandi,Hang Zhou,Hang Zhou,Lea Zillich,Rolf Adolfsson,Ingrid Agartz,Ingrid Agartz,Martin Alda,Martin Alda,Lars Alfredsson,Gulja Babadjanova,Lena Backlund,Lena Backlund,Bernhard T. Baune,Bernhard T. Baune,Bernhard T. Baune,Frank Bellivier,Susanne Bengesser,Wade H. Berrettini,Douglas Blackwood,Michael Boehnke,Anders D. Børglum,Anders D. Børglum,Gerome Breen,Vaughan J. Carr,Stanley V. Catts,Aiden Corvin,Nicholas John Craddock,Udo Dannlowski,Dimitris Dikeos,Tõnu Esko,Bruno Etain,Panagiotis Ferentinos,Panagiotis Ferentinos,Mark A. Frye,Janice M. Fullerton,Janice M. Fullerton,Micha Gawlik,Elliot S. Gershon,Fernando S. Goes,Melissa J. Green,Melissa J. Green,Maria Grigoroiu-Serbanescu,Joanna Hauser,Frans Henskens,Jan Hillert,Kyung Sue Hong,David M. Hougaard,David M. Hougaard,Christina M. Hultman,Kristian Hveem,Nakao Iwata,Assen Jablensky,Ian Jones,Lisa Jones,René S. Kahn,John R. Kelsoe,George Kirov,Mikael Landén,Mikael Landén,Marion Leboyer,Marion Leboyer,Cathryn M. Lewis,Qingqin S. Li,Jolanta Lissowska,Christine Lochner,Carmel M. Loughland,Nicholas G. Martin,Nicholas G. Martin,Carol A. Mathews,Fermín Mayoral,Susan L. McElroy,Andrew M. McIntosh,Francis J. McMahon,Ingrid Melle,Ingrid Melle,Patricia T. Michie,Lili Milani,Philip B. Mitchell,Gunnar Morken,Ole Mors,Ole Mors,Preben Bo Mortensen,Bryan J. Mowry,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Richard M. Myers,Benjamin M. Neale,Benjamin M. Neale,Caroline M. Nievergelt,Caroline M. Nievergelt,Merete Nordentoft,Merete Nordentoft,Markus M. Nöthen,Michael Conlon O'Donovan,Ketil J. Oedegaard,Tomas Olsson,Michael John Owen,Sara A. Paciga,C Pantelis,Carlos N. Pato,Michele T. Pato,George P. Patrinos,George P. Patrinos,Roy H. Perlis,Danielle Posthuma,Josep Antoni Ramos-Quiroga,Andreas Reif,Eva Z. Reininghaus,Marta Ribasés,Marcella Rietschel,Stephan Ripke,Stephan Ripke,Stephan Ripke,Guy A. Rouleau,Guy A. Rouleau,Takeo Saito,Ulrich Schall,Martin Schalling,Martin Schalling,Peter R. Schofield,Peter R. Schofield,Thomas G. Schulze,Laura J. Scott,Rodney J. Scott,Alessandro Serretti,Cynthia Shannon Weickert,Cynthia Shannon Weickert,Cynthia Shannon Weickert,Jordan W. Smoller,Jordan W. Smoller,Hreinn Stefansson,Kari Stefansson,Kari Stefansson,Eystein Stordal,Fabian Streit,Patrick F. Sullivan,Patrick F. Sullivan,Gustavo Turecki,Arne E. Vaaler,Eduard Vieta,John B. Vincent,Irwin D. Waldman,Thomas W. Weickert,Thomas W. Weickert,Thomas W. Weickert,Thomas Werge,Naomi R. Wray,John-Anker Zwart,John-Anker Zwart,John-Anker Zwart,Joanna M. Biernacka,John I. Nurnberger,Sven Cichon,Howard J. Edenberg,Howard J. Edenberg,Eli A. Stahl,Eli A. Stahl,Andrew McQuillin,Arianna Di Florio,Arianna Di Florio,Roel A. Ophoff,Ole A. Andreassen,Ole A. Andreassen +399 more
TL;DR: The authors performed a genome-wide association study of 41,917 bipolar disorder cases and 371,549 controls of European ancestry, which identified 64 associated genomic loci, including genes encoding targets of antipsychotics, calcium channel blockers, antiepileptics and anesthetics.