Showing papers in "European Neuropsychopharmacology in 2022"

TL;DR: The authors provided a critical overview on how the COVID-19 pandemic has impacted mental health and how human stress resilience has been shaped by the pandemic on the shorter and longer term.

TL;DR: This article provided a critical overview on how the COVID-19 pandemic has impacted mental health and how human stress resilience has been shaped by the pandemic on the shorter and longer term.

TL;DR: In this article, the effects of the COVID-19 pandemic on mental health were investigated and the final model revealed multiple vulnerabilities and an interplay leading from simple anxiety to probable depression and suicidality through distress.

TL;DR: In this paper , the effects of the COVID-19 pandemic on mental health were investigated using Chi-square tests, multiple forward stepwise linear regression analyses and Factorial Analysis of Variance (ANOVA) tested relations among variables.

TL;DR: In this article, the authors investigated the efficacy of Selective Serotonin Reuptake Inhibitor (SSRI) in treating post-COVID depression and found that 55 (92%) patients showed a clinical response to antidepressant.

TL;DR: In this article, the paradigm change from one-size-fits-all psychiatry to more personalized-psychiatry, where they distinguish between "precision psychiatry" and "stratified psychiatry".

TL;DR: In this article , the paradigm change from one-size-fits-all psychiatry to more personalized-psychiatry, where they distinguish between "precision psychiatry" and "stratified psychiatry".

TL;DR: In this paper , the authors investigated the efficacy of selective serotonin reuptake inhibitor (SSRI) in treating post-COVID depression and found that 55 (92%) patients showed a clinical response to antidepressant.

TL;DR: In this paper , a systematic review of the evidence concerning lithium efficacy separately for the phases and clinical facets of Bipolar disorder (BD) was carried out, where the authors used the PRISMA method to search the MEDLINE for Randomized Controlled trials, Post-hoc analyses and Meta-analyses and review papers up to August 1st 2020.

TL;DR: In this article , a systematic review and meta-analysis aims to consolidate the evidence from the highest quality randomized controlled trials (RCTs) published up to July 2021, overcoming the limitations of earlier reviews.

TL;DR: A review of different perspectives, their historical roots and discrepancies can be found in this paper , highlighting discrepancies among clinicians and researchers of the European collaboration on movement and sensorimotor/psychomotor functioning in schizophrenia and other psychoses.

TL;DR: In this paper , a critical review of the potential benefits of precision psychiatry is presented, focusing on the ethical challenges that must be addressed before accessing the potential benefit of clinical prediction models.

TL;DR: In this paper , the authors examined suicidal thoughts and behaviors and suicide trends in 2020 relative to 2019 as an approximation to the impact of the pandemic on suicidal behavior and death in the general population of Catalonia, Spain.

TL;DR: In this paper , a longitudinal study explored the frequency, severity and pattern of cognitive impairment and functional implications 1 year after hospitalisation with COVID-19 and its trajectory from 3 months after hospitalization.

TL;DR: In this paper, a pro-inflammatory state was suggested to activate indoleamine 2,3-dioxygenase which, in turn, increases the amount of tryptophan (Trp) converted into kynurenine (Kyn).

TL;DR: In this paper , a pro-inflammatory state was suggested to activate indoleamine 2,3-dioxygenase which, in turn, increases the amount of tryptophan (Trp) converted into kynurenine (Kyn).

TL;DR: In this article , the authors investigated associations between the gut microbiome and mental health outcomes in participants with PTSD (n = 79) and trauma-exposed controls (TECs) using 16S ribosomal RNA gene V4 amplicon sequencing and tested for associations with PTSDrelated variables of interest.

TL;DR: In this paper , the authors performed secondary analyses among 90 outpatients with moderate-severe depression (71% female, mean age 38 years) treated for 26 weeks with escitalopram or nortriptyline and measured 27 pro-and anti-inflammatory markers at week 0, 8, 12, and 26 and calculated composite inflammation scores.

TL;DR: In this paper , a large pharmacovigilance database was used to identify clozapine-related DRESS cases, even if otherwise reported and provide a clinical overview of these cases.

TL;DR: In this paper , a double-blind parallel randomised controlled trial at three mental health care centers in the Netherlands was conducted to examine whether cannabidiol (CBD), a hydrolysis inhibitor of the endogenous CB1 receptor agonist anandamide (AEA), would enhance the effects of exposure therapy in treatment refractory patients with anxiety disorders.

TL;DR: In this article , a randomized, double-blind, placebo-controlled, crossover study with 24 healthy volunteers receiving 50 μg lysergic acid diethylamide (LSD) or an inactive placebo was conducted to investigate the potential of LSD to sub-acutely change cognition.

TL;DR: In this article, the authors used positron emission tomography (PET) of the monoamine oxidase (MAO)-B probe to test the hypothesis that levels of MAO-B, an index of astrocyte levels is decreased in PTSD.

TL;DR: In this article , the authors used positron emission tomography (PET) of the monoamine oxidase (MAO)-B probe to test the hypothesis that levels of MAO-B, an index of astrocyte levels is decreased in PTSD.

TL;DR: In this paper , a review focusing on different paradigms of stress (prenatal stress, maternal separation, social isolation and social defeat stress) and immune challenges (immune activation in pregnancy) and the subsequent alterations in several biological and behavioral domains at different time points of animals' life.

TL;DR: In this article , the authors investigated the relationship between multiple measures of epigenetic aging acceleration with clinical, functioning, and cognitive outcomes in patients with bipolar disorder and controls, and found significant group-dependent interactions between epigenetic factors to the aging-related cognitive decline and premature mortality reported in BD patients.

TL;DR: In this article , the authors investigated the possible association of polygenic risk scores (PRSs) for bipolar disorder, MDD, neuroticism, and schizophrenia (SCZ) with antidepressant non-response or non-remission in patients with MDD.

TL;DR: In this article , the authors found that reduced GSH levels may be associated with depressive symptoms and cerebral white matter hypodensities/hyperintensities (WMH) in COVID-19 survivors.