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Stephan Ripke

Researcher at Broad Institute

Publications -  311
Citations -  80990

Stephan Ripke is an academic researcher from Broad Institute. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 97, co-authored 278 publications receiving 63650 citations. Previous affiliations of Stephan Ripke include Icahn School of Medicine at Mount Sinai & University of Texas Southwestern Medical Center.

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Common risk variants identified in autism spectrum disorder

Jakob Grove, +76 more
- 25 Nov 2017 - 
TL;DR: It is established that GWAS performed at scale will be much more productive in the near term in ASD, just as it has been in a broad range of important psychiatric and diverse medical phenotypes.

Defining the role of common variation in the genomic and biological architecture of adult human height

Andrew R. Wood, +444 more
TL;DR: The results indicate a genetic architecture for human height that is characterized by a very large but finite number of causal variants, including mTOR, osteoglycin and binding of hyaluronic acid.
Journal ArticleDOI

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

Wouter J. Peyrot, +27 more
- 15 Jul 2018 - 
TL;DR: In this paper, the meta-analytic evidence for interaction between major depressive disorder (MDD) and childhood trauma (CT) was found, which suggests that the previously reported interaction effects, although both statistically significant, can best be interpreted as chance findings.
Journal ArticleDOI

Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis.

Dorothée Diogo, +35 more
- 10 Jan 2013 - 
TL;DR: The results indicate that variants within the protein-coding portion of a subset of biological candidate genes identified by GWASs contribute to the risk of RA.

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

Christel M. Middeldorp, +67 more
TL;DR: For example, this article examined the genetic association between personality and major depressive disorder (MDD) and bipolar disorder (BD) by applying polygenic scores for neuroticism, extraversion, openness to experience, agreeableness and conscientiousness to both disorders.