S
Stephen Hanessian
Researcher at Université de Montréal
Publications - 764
Citations - 19319
Stephen Hanessian is an academic researcher from Université de Montréal. The author has contributed to research in topics: Total synthesis & Bicyclic molecule. The author has an hindex of 65, co-authored 754 publications receiving 18572 citations. Previous affiliations of Stephen Hanessian include Parke-Davis & University of California, Irvine.
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Journal ArticleDOI
Systematic Investigation of Tether Length and Phosphorus Configuration in Backbone Constrained Macrocyclic Nucleic Acids to Modulate Binding Kinetics for RNA.
Tamilselvan Rajasekaran,Graeme C. Freestone,Rodrigo Galindo-Murillo,B. Lugato,Hans Gaus,Michael T. Migawa,Eric E. Swayze,Thomas E. Cheatham,Punit P. Seth,Stephen Hanessian +9 more
TL;DR: In this article , the authors describe the synthesis of all eight P-stereoisomers of macrocyclic 12-, 13-, 14-, and 16-membered hydrocarbon-bridged nucleotide trimers, their incorporation into ONs, and biophysical characterization of the modified ONs.
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Stereocontrolled Solution and Solid Phase Enolate Alkylations and Hydroxylations — Generation of Three and Four Contiguous Stereogenic Carbon Atoms in Acyclic Systems.
TL;DR: In this paper, the enolates of γ-alkoxy-α-methyl pentanoates can be alkylated with allylic and benzylic halides in solution and on solid phase with high 2,3-selectivity.
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Structure of a Chiral Bicyclic β‐Hydroxyphosphonamide ‐ An Asymmetric Olefination Intermediate, C25H41N2O2P.
TL;DR: In this article, a composition of cyclohexane attache a un groupe phosphoryl de coordination tetraedrique is presented, which is composed of a cyclophenylmethyl attache and a phenylmethyl de configuration.
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Synthesis of Chemically and Functionally Diverse Scaffolds from Pentaerythritol
TL;DR: Pentaerythritol (2,2-bis-hydroxymethyl-propane-1,3-diol) was converted into a series of mono-, di-, and trisubstituted derivatives by systematic che...
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A Synthetic Strategy for Tricholomic Acid and Acivicin.
Stephen Hanessian,Benoit Vanasse +1 more
TL;DR: Aldol condensation of N-pyruvilideneglycinatoaquocopper(II) and an optically active aldehyde derived from S-malic acid as the key bond-forming reaction was developed in this article.