S
Sterne Jac.
Researcher at University of Bristol
Publications - 4
Citations - 2211
Sterne Jac. is an academic researcher from University of Bristol. The author has contributed to research in topics: Odds ratio & Placebo. The author has an hindex of 3, co-authored 4 publications receiving 1046 citations.
Papers
More filters
Journal ArticleDOI
Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis.
Sterne Jac.,Srinivas Murthy,Janet V. Diaz,Arthur S. Slutsky,Judit Villar,Derek C. Angus,Djillali Annane,Azevedo Lcp.,Otavio Berwanger,Alexandre Biasi Cavalcanti,Dequin P-F.,Dequin P-F.,Bin Du,Jonathan Emberson,David Fisher,Bruno Giraudeau,Anthony C. Gordon,Anders Granholm,Cameron Green,Richard Haynes,N Heming,Higgins Jpt.,Higgins Jpt.,Peter Horby,Peter Jüni,Martin J Landray,A. Le Gouge,Marie Leclerc,Wei Shen Lim,Flávia Ribeiro Machado,Colin McArthur,Colin McArthur,Ferhat Meziani,Morten Hylander Møller,Anders Perner,M W Petersen,Jelena Savović,Jelena Savović,Bruno Martins Tomazini,Viviane C Veiga,Steven A R Webb,John C. Marshall +41 more
TL;DR: A prospective meta-analysis that pooled data from 7 randomized clinical trials that evaluated the efficacy of corticosteroids in 1703 critically ill patients with COVID-19 found that low-dose dexamethasone reduced mortality in hospitalized patients with Cohen's disease who required respiratory support.
Journal ArticleDOI
Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis.
Manu Shankar-Hari,Claire L Vale,Peter J. Godolphin,David Fisher,Higgins Jpt.,Francesca Spiga,Jelena Savović,Jelena Savović,Jayne F. Tierney,Gabriel Baron,Julie Benbenishty,Lindsay R. Berry,N Broman,Alexandre Biasi Cavalcanti,R Colman,S. De Buyser,Derde Lpg.,P Domingo,S F Omar,A Fernandez-Cruz,T Feuth,F Garcia,R Garcia-Vicuna,I Gonzalez-Alvaro,Anthony C. Gordon,Richard Haynes,Olivier Hermine,Peter Horby,Nora Horick,K Kumar,B N Lambrecht,Martin J Landray,L Leal,D J Lederer,Elizabeth Lorenzi,X Mariette,N Merchante,N A Misnan,S V Mohan,M C Nivens,J Oksi,J A Perez-Molina,R Pizov,R Porcher,S Postma,R Rajasuriar,Athimalaipet V Ramanan,P Ravaud,Pankti Reid,Abraham Rutgers,A Sancho-Lopez,Todd B. Seto,S Sivapalasingam,A S Soin,Natalie Staplin,John H. Stone,Garth W. Strohbehn,J Sunden-Cullberg,J Torre-Cisneros,L W Tsai,H. van Hoogstraten,T. van Meerten,Viviane C Veiga,P E Westerweel,Srinivas Murthy,Janet V. Diaz,John C. Marshall,Sterne Jac. +67 more
TL;DR: In this article, a prospective meta-analysis of clinical trials of patients hospitalized for COVID-19, administration of IL-6 antagonists, compared with usual care or placebo, was associated with lower 28-day all-cause mortality.
Journal ArticleDOI
Design and preliminary recruitment results of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP).
Emma L Turner,Chris Metcalfe,Jenny L Donovan,Sian Noble,Sterne Jac.,J A Lane,Kerry N L Avery,L Down,Eleanor I Walsh,Michael Davis,Yoav Ben-Shlomo,Steven E. Oliver,Simon Evans,Peter Brindle,Naomi J Williams,Laura J Hughes,Elizabeth M Hill,Charlotte F Davies,Siaw Yein Ng,David E. Neal,Freddie C. Hamdy,Richard M. Martin +21 more
TL;DR: The CAP trial successfully met its recruitment targets and will make an important contribution to international understanding of PSA-based prostate cancer screening, with little evidence of differences between trial arms in measured baseline characteristics of the consenting GP practices.
Posted ContentDOI
Comparative effectiveness of ChAdOx1 versus BNT162b2 COVID-19 vaccines in Health and Social Care workers in England: a cohort study using OpenSAFELY
William J Hulme,Elizabeth Williamson,Green Aca.,Krishnan Bhaskaran,Helen Mcdonald,Christopher T Rentsch,Anna Schultze,John Tazare,Helen J Curtis,Andrew Walker,Laurie A. Tomlinson,Tom Palmer,E Horne,Brian MacKenna,Caroline E Morton,Amir Mehrkar,Louis Fisher,Bacon Scj.,David M. Evans,Peter Inglesby,George Hickman,Simon Davy,Tom Ward,Richard Croker,Rosalind M Eggo,Wong Ays.,Rohini Mathur,Kevin Wing,Harriet Forbes,Daniel Grint,Ian J. Douglas,Evans Sjw.,Liam Smeeth,Christopher M. Bates,Jonathan Cockburn,John Parry,Frank Hester,Sam Harper,Sterne Jac.,Miguel A. Hernán,Ben Goldacre +40 more
TL;DR: In this article, the authors compared the effectiveness of ChAdOx1 versus BNT162b2 in 1/3 million health and social care workers vaccinated between 4 January and 28 February 2021.