Susan A. Weaver

TL;DR: These data should be used by individuals contemplating a clinical trial to determine if prophylactic anticonvulsants are effective in subsets of brain tumour patients (e.g. only anaplastic astrocytomas).

TL;DR: Combined CT + RT led to longer disease control and survival than did CT or RT alone in cases with no 1p19q deletion, and PCV appeared to offer longer disease Control than temozolomide but without a clear survival advantage.

TL;DR: Analysis of serial serum samples obtained from 47 patients for four angiogenic peptides failed to show a significant correlation with response or survival for three of the peptides, but higher vascular endothelial growth factor levels showed a trend toward correlation with decreased OS and PFS.

TL;DR: Although a majority of patients have died, long-term survival is possible in patients who achieve a complete response to treatment, particularly those who present with CNS involvement or involvement of the CNS is the sole site of relapsed disease.

TL;DR: Patients with 1p19q codeleted tumors were significantly more likely to receive CT alone (with temozolomide), whereas RT with temozlomide was a significantly more common treatment strategy than either CT or RT alone in cases with no deletion (P < .0001).