S
Susana González
Researcher at Norwegian University of Science and Technology
Publications - 91
Citations - 6527
Susana González is an academic researcher from Norwegian University of Science and Technology. The author has contributed to research in topics: Chemistry & Water quality. The author has an hindex of 33, co-authored 83 publications receiving 5601 citations. Previous affiliations of Susana González include Spanish National Research Council & Bayer.
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Journal ArticleDOI
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
María Mittelbrunn,Cristina Gutiérrez-Vázquez,Carolina Villarroya-Beltri,Susana González,Fátima Sánchez-Cabo,Manuel A. González,Antonio Bernad,Francisco Sánchez-Madrid +7 more
TL;DR: It is shown that exosomes of T, B and dendritic immune cells contain microRNA (miRNA) repertoires that differ from those of their parent cells, and that miRNAs transferred during immune synapsis are able to modulate gene expression in recipient cells.
Journal ArticleDOI
Geriatric muscle stem cells switch reversible quiescence into senescence
Pedro Sousa-Victor,Pedro Sousa-Victor,Susana Gutarra,Laura García-Prat,Javier Rodríguez-Ubreva,Laura Ortet,Vanessa Ruiz-Bonilla,Mercè Jardí,Esteban Ballestar,Susana González,Antonio L. Serrano,Eusebio Perdiguero,Pura Muñoz-Cánoves,Pura Muñoz-Cánoves +13 more
TL;DR: It is reported that geriatric satellite cells are incapable of maintaining their normal quiescent state in muscle homeostatic conditions, and that this irreversibly affects their intrinsic regenerative and self-renewal capacities.
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A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases (Nature Structural and Molecular Biology (2008) 15, (268-279))
Roberta Benetti,Susana Gonzalo,Isabel Jaco,Purificación Mũoz,Susana González,Stefan Schoeftner,Elizabeth P. Murchison,Thomas Andl,Taiping Chen,Peter Klatt,En Li,Manuel Serrano,Sarah E. Millar,Gregory J. Hannon,Maria A. Blasco +14 more
TL;DR: A pathway by which miR-290 directly regulates Rbl2-dependent Dnmt expression is identified, indirectly affecting telomere-length homeostasis.
Journal ArticleDOI
miR-181b negatively regulates activation-induced cytidine deaminase in B cells
Virginia G. de Yébenes,Laura Belver,David G. Pisano,Susana González,Aranzazu Villasante,Carlo M. Croce,Lin He,Almudena R. Ramiro +7 more
TL;DR: Evidence is provided for a new regulatory mechanism that restricts AID activity and can therefore be relevant to prevent B cell malignant transformation.
Journal ArticleDOI
Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest.
I. Hidalgo,Antonio Herrera-Merchan,José M. Ligos,Laura Carramolino,Javier Nuñez,Fernando Martínez,Orlando Domínguez,Miguel Torres,Susana González +8 more
TL;DR: Ezh1 maintains repopulating HSCs in a slow-cycling, undifferentiated state, protecting them from senescence, and suggests that Ezh1 is an important histone methyltransferase for HSC maintenance.