S
Sushrut S. Waikar
Researcher at Boston University
Publications - 288
Citations - 16295
Sushrut S. Waikar is an academic researcher from Boston University. The author has contributed to research in topics: Kidney disease & Acute kidney injury. The author has an hindex of 56, co-authored 244 publications receiving 12435 citations. Previous affiliations of Sushrut S. Waikar include Brigham and Women's Hospital & Washington University in St. Louis.
Papers
More filters
Journal ArticleDOI
Biomarkers for the diagnosis of acute kidney injury.
TL;DR: Clinical studies of newer biomarkers that may permit earlier and more accurate identification of acute kidney injury are summarized and hold the potential to transform the care of patients with renal disease.
Journal ArticleDOI
Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition
Girish S. Naik,Sushrut S. Waikar,Sushrut S. Waikar,Alistair E. W. Johnson,Elizabeth I. Buchbinder,Rizwan Haq,F. Stephen Hodi,Jonathan D. Schoenfeld,Jonathan D. Schoenfeld,Patrick A. Ott +9 more
TL;DR: The findings support the existence of an “obesity paradox” restricted to overweight/Class-I obesity in the real-world setting and suggest that sarcopenia or direct measures of body mass composition may be more suitable predictors of survival in melanoma patients treated with PD-1 blockade (monotherapy/combination).
Journal ArticleDOI
ADAM17 substrate release in proximal tubule drives kidney fibrosis
Eirini Kefaloyianni,Muthu Lakshmi Muthu,Jakob Kaeppler,Xiaoming Sun,Venkata S. Sabbisetti,Athena Chalaris,Stefan Rose-John,Eitan Wong,Irit Sagi,Sushrut S. Waikar,Helmut G. Rennke,Benjamin D. Humphreys,Joseph V. Bonventre,Andreas Herrlich +13 more
TL;DR: In vitro, in proximal tubule cells, it is shown that AREG has unique profibrotic actions that are potentiated by TNFα-induced AREG cleavage, and this results indicate that targeting of the ADAM17 pathway represents a therapeutic target for human kidney fibrosis.
Book ChapterDOI
Implementation of novel biomarkers in the diagnosis, prognosis, and management of acute kidney injury: executive summary from the tenth consensus conference of the Acute Dialysis Quality Initiative (ADQI).
Peter A. McCullough,Josée Bouchard,Sushrut S. Waikar,Edward D. Siew,Zoltan H. Endre,Stuart L. Goldstein,Jay L. Koyner,Etienne Macedo,Kent Doi,Salvatore Di Somma,Andrew Lewington,Ravi Thadhani,Raj Chakravarthi,Can Ice,Mark D. Okusa,Jacques Duranteau,Peter Doran,Li Yang,Bertrand L. Jaber,Shane Meehan,John A. Kellum,Michael Haase,Patrick T. Murray,Dinna N. Cruz,Alan S. Maisel,Sean M. Bagshaw,Lakhmir S. Chawla,Ravindra L. Mehta,Andrew D. Shaw,Claudio Ronco +29 more
TL;DR: The ADQI (Acute Dialysis Quality Initiative) had its Ninth Consensus Conference dedicated to synthesis and formulation of the existing literature on biomarkers for the detection of acute kidney injury in a variety of settings.
Journal ArticleDOI
Weekend Hospital Admission, Acute Kidney Injury, and Mortality
Matthew T. James,Ron Wald,Chaim M. Bell,Marcello Tonelli,Brenda R. Hemmelgarn,Sushrut S. Waikar,Glenn M. Chertow +6 more
TL;DR: Among patients hospitalized with AKI, weekend admission is associated with a higher risk for death compared with admission on a weekday, and increased mortality was also associated with weekend admission among patients withAKI as a secondary diagnosis across a spectrum of co-existing medical diagnoses.