S
Suzanne C. Burns
Researcher at University of Texas Health Science Center at San Antonio
Publications - 20
Citations - 1789
Suzanne C. Burns is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: RNA-binding protein & RNA splicing. The author has an hindex of 15, co-authored 20 publications receiving 1518 citations. Previous affiliations of Suzanne C. Burns include Greehey Children's Cancer Research Institute.
Papers
More filters
Journal ArticleDOI
Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line
Christine Vogel,Raquel de Sousa Abreu,Daijin Ko,Shu-Yun Le,Bruce A. Shapiro,Suzanne C. Burns,Devraj Sandhu,Daniel R. Boutz,Edward M. Marcotte,Luiz O. F. Penalva +9 more
TL;DR: The absolute protein and mRNA concentration measurements for >1000 human genes described here represent one of the largest datasets currently available, and reveal both general trends and specific examples of post‐transcriptional regulation.
Journal ArticleDOI
Site identification in high-throughput RNA–protein interaction data
Philip J. Uren,Emad Bahrami-Samani,Suzanne C. Burns,Mei Qiao,Fedor V. Karginov,Emily Hodges,Gregory J. Hannon,Jeremy R. Sanford,Luiz O. F. Penalva,Andrew D. Smith +9 more
TL;DR: This work introduces a method for site identification which can be applied on all variations of CLIP and RIP-seq technologies, and accurately models the underlying read-count distributions, and allows external covariates, such as transcript abundance, to inform the site identification process.
Journal ArticleDOI
Before It Gets Started: Regulating Translation at the 5' UTR.
Patrícia R. Araújo,Kihoon Yoon,Daijin Ko,Andrew D. Smith,Mei Qiao,Uthra Suresh,Suzanne C. Burns,Luiz O. F. Penalva,Luiz O. F. Penalva +8 more
TL;DR: Important aspects of 5′ UTR-mediated regulation are discussed by providing an overview of the characteristics and the function of the main elements present in this region, like uORF (upstream open reading frame), secondary structures, and RBPs binding motifs and different mechanisms of translation regulation.
Journal ArticleDOI
Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma
Bruna R. Correa,Patrícia R. Araújo,Mei Qiao,Suzanne C. Burns,Chen Chen,Richard Schlegel,Seema Agarwal,Pedro A. F. Galante,Luiz O. F. Penalva +8 more
TL;DR: This study provides new insights into how RBPs, and specifically SNRPB, regulate gene expression and directly impact GBM development.
Journal ArticleDOI
Genomic Analyses of Musashi1 Downstream Targets Show a Strong Association with Cancer-related Processes
Raquel de Sousa Abreu,Patricia C. Sanchez-Diaz,Christine Vogel,Suzanne C. Burns,Daijin Ko,Tarea L. Burton,Dat T. Vo,Soudhamini Chennasamudaram,Shu Yun Le,Bruce A. Shapiro,Luiz O. F. Penalva +10 more
TL;DR: The proteomics study revealed that Msi1 can have either positive or negative effects on gene expression of its direct targets and could function as a master regulator during development and tumor formation.