T
Talmadge E. King
Researcher at University of California, San Francisco
Publications - 215
Citations - 48569
Talmadge E. King is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Idiopathic pulmonary fibrosis & Interstitial lung disease. The author has an hindex of 88, co-authored 214 publications receiving 43290 citations. Previous affiliations of Talmadge E. King include National Jewish Health & University of California.
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Journal ArticleDOI
Analyses of Efficacy End Points in a Controlled Trial of Interferon-γ1b for Idiopathic Pulmonary Fibrosis
Talmadge E. King,Sharon Safrin,Karen M. Starko,Kevin K. Brown,Paul W. Noble,Ganesh Raghu,David A. Schwartz +6 more
TL;DR: It is concluded that mortality is the most inclusive end point for future trials of IFN- gamma1b in patients with IPF, and that a > 10% decrement in the percentage of predicted FVC represents a valid measure of disease progression.
Journal ArticleDOI
Idiopathic pulmonary fibrosis: clinically meaningful primary endpoints in phase 3 clinical trials.
Ganesh Raghu,Harold R. Collard,Kevin J. Anstrom,Kevin R. Flaherty,Thomas R. Fleming,Talmadge E. King,Fernando J. Martinez,Kevin K. Brown +7 more
TL;DR: All-cause mortality and all-cause nonelective hospitalization are believed to be the endpoints that best meet criteria for clinical efficacy in idiopathic pulmonary fibrosis.
Journal ArticleDOI
The SF-36 and SGRQ: validity and first look at minimum important differences in IPF
Jeffrey J. Swigris,Kevin K. Brown,Juergen Behr,Roland M. du Bois,Talmadge E. King,Ganesh Raghu,Frederick S. Wamboldt +6 more
TL;DR: In IPF, the SF-36 and SGRQ possess reasonable validity for differentiating subjects whose disease severity changes over time, and more studies are needed to continue the validation process, to refine estimates of the MIDs, and to determine if a disease-specific instrument will perform better than either of these.
Journal ArticleDOI
Does Chronic Microaspiration Cause Idiopathic Pulmonary Fibrosis
Joyce S. Lee,Harold R. Collard,Ganesh Raghu,Matthew P. Sweet,Steven R. Hays,Guilherme M. Campos,Jeffrey A. Golden,Talmadge E. King +7 more
TL;DR: This review aims to describe the relationship between chronic microaspiration and idiopathic pulmonary fibrosis by laying out the clinical and biologic rationale for this relationship and exploring the scientific evidence available.
Journal ArticleDOI
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.
Timothy S. Blackwell,Andrew M. Tager,Zea Borok,Bethany B. Moore,David A. Schwartz,Kevin J. Anstrom,Ziv Bar-Joseph,Peter B. Bitterman,Michael R. Blackburn,William Bradford,Kevin K. Brown,Harold A. Chapman,Harold R. Collard,Gregory P. Cosgrove,Robin R. Deterding,Ramona Doyle,Kevin R. Flaherty,Christine Kim Garcia,James S. Hagood,Craig A. Henke,Erica L. Herzog,Cory M. Hogaboam,Jeffrey C. Horowitz,Talmadge E. King,James E. Loyd,William Lawson,Clay B. Marsh,Paul W. Noble,Imre Noth,Dean Sheppard,Julie Olsson,Luis A. Ortiz,Thomas G. O'Riordan,Tim D. Oury,Ganesh Raghu,Jesse Roman,Patricia J. Sime,Thomas H. Sisson,Daniel J. Tschumperlin,Shelia M. Violette,Timothy E. Weaver,Rebecca G. Wells,Eric S. White,Naftali Kaminski,Fernando J. Martinez,Thomas A. Wynn,Victor J. Thannickal,Jerry P. Eu +47 more
TL;DR: Recommendations from a workshop aimed at coordinating research efforts and accelerating the development of IPF therapies provide a basis for directing future research and strategic planning by scientific, professional, and patient communities and the NHLBI.