T
Taras Balandin
Researcher at Forschungszentrum Jülich
Publications - 39
Citations - 1220
Taras Balandin is an academic researcher from Forschungszentrum Jülich. The author has contributed to research in topics: Barnase & Rhodopsin. The author has an hindex of 17, co-authored 34 publications receiving 917 citations. Previous affiliations of Taras Balandin include Russian Academy of Sciences.
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Journal ArticleDOI
Structural insights into ion conduction by channelrhodopsin 2
Oleksandr Volkov,Kirill Kovalev,Vitaly Polovinkin,Valentin Borshchevskiy,Christian Bamann,R. Astashkin,R. Astashkin,Egor Marin,Alexander Popov,Taras Balandin,Dieter Willbold,Dieter Willbold,Georg Büldt,Ernst Bamberg,Valentin Gordeliy,Valentin Gordeliy +15 more
TL;DR: The high-resolution structure of channelrhodopsin 2, the most widely used optogenetics tool, as well as the structure of a mutant with a longer open-state lifetime are described, providing a basis for designing better optogenetic tools.
Journal ArticleDOI
Mechanism of transmembrane signaling by sensor histidine kinases
Ivan Gushchin,Igor Melnikov,Vitaly Polovinkin,Vitaly Polovinkin,Andrii Ishchenko,Anastasia Yuzhakova,Pavel Buslaev,Gleb Bourenkov,Sergei Grudinin,Sergei Grudinin,Sergei Grudinin,Ekaterina Round,Taras Balandin,Valentin Borshchevskiy,Dieter Willbold,Gordon A. Leonard,Georg Büldt,Alexander Popov,Valentin Gordeliy,Valentin Gordeliy +19 more
TL;DR: The structures reveal the mechanism of transmembrane signal transduction in NarQ and show that binding of ligand induces displacement of the sensor domain helices by ~0.5 to 1 Å and demonstrate that the signaling-associated conformational changes in the TM domain do not need to be symmetric.
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Crystal structure of a light-driven sodium pump
Ivan Gushchin,Vitaly Shevchenko,Vitaly Shevchenko,Vitaly Polovinkin,Kirill Kovalev,Alexey Alekseev,Ekaterina Round,Valentin Borshchevskiy,Taras Balandin,Alexander Popov,Thomas Gensch,Christoph Fahlke,Christian Bamann,Dieter Willbold,Georg Büldt,Ernst Bamberg,Valentin Gordeliy +16 more
TL;DR: The structures of Krokinobacter eikastus rhodopsin 2 show that the sodium ion is bound outside the protein at the oligomerization interface, that the ion-release cavity is capped by a unique N-terminal α-helix and that the Ion-uptake cavity is unexpectedly large and open to the surface.
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Inward H$^+$ pump xenorhodopsin: Mechanism and alternative optogenetic approach
Vitaly Shevchenko,Vitaly Shevchenko,Thomas Mager,Kirill Kovalev,Kirill Kovalev,Vitaly Polovinkin,Vitaly Polovinkin,Alexey Alekseev,Alexey Alekseev,Josephine Juettner,Igor Chizhov,Christian Bamann,Charlotte D. Vavourakis,Rohit Ghai,Ivan Gushchin,Valentin Borshchevskiy,A. V. Rogachev,A. V. Rogachev,Igor Melnikov,Alexander Popov,Taras Balandin,Francisco Rodriguez-Valera,Dietmar J. Manstein,G. Bueldt,Ernst Bamberg,Valentin Gordeliy,Valentin Gordeliy +26 more
TL;DR: It is demonstrated that the NsXeR is a powerful pump, which is able to elicit action potentials in rat hippocampal neuronal cells up to their maximal intrinsic firing frequency, and they are an alternative to the well-known cation-selective channelrhodopsins.
Journal ArticleDOI
Barnase as a New Therapeutic Agent Triggering Apoptosis in Human Cancer Cells
E. F. Edelweiss,Taras Balandin,Julia L. Ivanova,Gennady V. Lutsenko,O. G. Leonova,Vladimir I. Popenko,Alexander M. Sapozhnikov,Sergey M. Deyev +7 more
TL;DR: It is demonstrated that barnase is a potent toxic agent for targeting to cancer cells and resistant to RI.