T
Thomas Bienert
Researcher at University of Freiburg
Publications - 15
Citations - 443
Thomas Bienert is an academic researcher from University of Freiburg. The author has contributed to research in topics: Connectome & Resting state fMRI. The author has an hindex of 9, co-authored 15 publications receiving 286 citations. Previous affiliations of Thomas Bienert include University Medical Center Freiburg.
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Journal ArticleDOI
Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis
Joanes Grandjean,Carola Canella,Cynthia Anckaerts,Gulebru Ayranci,Salma Bougacha,Thomas Bienert,David Buehlmann,Ludovico Coletta,Daniel Gallino,Natalia Gass,Clément M. Garin,Nachiket A. Nadkarni,Neele S. Hübner,Meltem Karatas,Yuji Komaki,Silke Kreitz,Francesca Mandino,Anna E. Mechling,Chika Sato,Katja Sauer,Disha Shah,Sandra Strobelt,Norio Takata,Isabel Wank,Tong Wu,Noriaki Yahata,Ling Yun Yeow,Yohan Yee,Ichio Aoki,M. Mallar Chakravarty,Wei-Tang Chang,Marc Dhenain,Dominik von Elverfeldt,Laura-Adela Harsan,Andreas Hess,Tianzi Jiang,Georgios A. Keliris,Jason P. Lerch,Andreas Meyer-Lindenberg,Hideyuki Okano,Markus Rudin,Alexander Sartorius,Annemie Van der Linden,Marleen Verhoye,Wolfgang Weber-Fahr,Nicole Wenderoth,Valerio Zerbi,Alessandro Gozzi +47 more
TL;DR: A multi-centre comparison of 17 mouse rsfMRI datasets via a common image processing and analysis pipeline is described, reporting the reproducible identification of several large-scale resting-state networks (RSN), including a mouse default-mode network, in the majority of datasets.
Journal ArticleDOI
The connectomics of brain demyelination: Functional and structural patterns in the cuprizone mouse model.
Neele S. Hübner,Anna E. Mechling,Hsu-Lei Lee,Marco Reisert,Thomas Bienert,Jürgen Hennig,Dominik von Elverfeldt,Laura-Adela Harsan,Laura-Adela Harsan +8 more
TL;DR: It is demonstrated via non‐invasive resting state fMRI that intrinsic functional connectivity is fundamentally reorganized in demyelinated mouse brain, paralleled by widespread damage of structural scaffolding and strong modulations of default mode and hippocampal networks.
Journal ArticleDOI
Mu Opioid Receptors in Gamma-Aminobutyric Acidergic Forebrain Neurons Moderate Motivation for Heroin and Palatable Food
Pauline Charbogne,Pauline Charbogne,Olivier Gardon,Elena Martín-García,Helen L. Keyworth,Aya Matsui,Anna E. Mechling,Thomas Bienert,Taufiq Nasseef,Anne Robé,Luc Moquin,Emmanuel Darcq,Sami Ben Hamida,Patricia Robledo,Audrey Matifas,Katia Befort,Katia Befort,Katia Befort,Claire Gaveriaux-Ruff,Laura-Adela Harsan,Laura-Adela Harsan,Dominik von Elverfeldt,Jürgen Hennig,Alain Gratton,Ian Kitchen,Alexis Bailey,Alexis Bailey,Veronica A. Alvarez,Rafael Maldonado,Brigitte L. Kieffer,Brigitte L. Kieffer +30 more
TL;DR: Beyond a well-established role in reward processing, operating at the level of local ventral tegmental area neurons, MORs also moderate motivation for appetitive stimuli within forebrain circuits that drive motivated behaviors.
Journal ArticleDOI
Deletion of the mu opioid receptor gene in mice reshapes the reward-aversion connectome
Anna E. Mechling,Tanzil Mahmud Arefin,Hsu-Lei Lee,Thomas Bienert,Marco Reisert,Sami Ben Hamida,Emmanuel Darcq,Aliza T. Ehrlich,Claire Gaveriaux-Ruff,Maxime Parent,Pedro Rosa-Neto,Juergen Hennig,Dominik von Elverfeldt,Brigitte L. Kieffer,Laura-Adela Harsan,Laura-Adela Harsan +15 more
TL;DR: It is demonstrated that the main receptor for morphine predominantly shapes the so-called reward/aversion circuitry, with major influence on negative affect centers, in mice manipulated by targeted deletion of the Oprm1 gene.
Journal ArticleDOI
Atlas registration for edema-corrected MRI lesion volume in mouse stroke models
Stefan Koch,Susanne Mueller,Marco Foddis,Thomas Bienert,Dominik von Elverfeldt,Felix Knab,Tracy D. Farr,Tracy D. Farr,René Bernard,Monika Dopatka,André Rex,Ulrich Dirnagl,Ulrich Dirnagl,Christoph Harms,Philipp Boehm-Sturm +14 more
TL;DR: A mathematical framework to correct lesion size for edema which is based on manual delineation of the lesion and hemispheres is improved and a novel MATLAB toolbox to register mouse brain MR images to the Allen brain atlas is presented.