T
Thomas F. Schilling
Researcher at University of California, Irvine
Publications - 164
Citations - 23012
Thomas F. Schilling is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Zebrafish & Neural crest. The author has an hindex of 57, co-authored 150 publications receiving 20932 citations. Previous affiliations of Thomas F. Schilling include University of California, Berkeley & Max Planck Society.
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Journal ArticleDOI
Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos.
Louise A Brown,Adam Rodaway,Thomas F. Schilling,Trevor Jowett,Philip W. Ingham,R K Patient,Andrew D. Sharrocks +6 more
TL;DR: Fli-1 expression was initiated normally in cloche embryos, indicating that induction of fli-1 is one of the earliest indicators of haemangioblast formation and that cloche has previously unsuspected roles at multiple stages in the formation of the vasculature.
Journal ArticleDOI
Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull.
Naoyuki Wada,Yashar Javidan,Sarah Nelson,Thomas J. Carney,Robert N. Kelsh,Thomas F. Schilling +5 more
TL;DR: A novel role for Shh is suggested in the movements of neural crest cells at the midline, as well as in their differentiation into cartilage, and help to explain why both skeletal fusions and palatal clefting are associated with the loss of Hh signaling in holoprosencephalic humans.
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Protective versus Conventional Ventilation for Surgery: A Systematic Review and Individual Patient Data Meta-analysis
Ary Serpa Neto,Ary Serpa Neto,Sabrine N.T. Hemmes,Carmen Silvia Valente Barbas,Martin Beiderlinden,Michelle Biehl,Jan M. Binnekade,Jaume Canet,Ana Fernandez-Bustamante,Emmanuel Futier,Ognjen Gajic,Göran Hedenstierna,Markus W. Hollmann,Samir Jaber,Alf Kozian,Marc Licker,Wen Qian Lin,Andrew Maslow,Stavros G. Memtsoudis,Dinis dos Reis Miranda,Pierre Moine,Thomas Ng,Domenico Paparella,Christian Putensen,Marco Ranieri,Federica Scavonetto,Thomas F. Schilling,Werner Schmid,Gabriele Selmo,Paolo Severgnini,Juraj Sprung,Sugantha Sundar,Daniel Talmor,Tanja A. Treschan,Carmen Unzueta,Toby N. Weingarten,Esther K. Wolthuis,Hermann Wrigge,Marcelo Gama de Abreu,Paolo Pelosi,Marcus J. Schultz +40 more
TL;DR: These data support the beneficial effects of ventilation with use of low VT in patients undergoing surgery and the role of intraoperative higher PEEP to prevent PPC during nonopen abdominal surgery.
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Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo.
TL;DR: Using cell transplantation and implantation of RA-coated beads into RA-deficient zebrafish embryos, it is demonstrated that RA can directly convey graded positional information over long distances, and expression of Cyp26a1, the major RA-degrading enzyme during gastrulation, is under complex feedback and feedforward control.
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sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development.
TL;DR: The results support a model for dorsoventral patterning of the gnathostome pharyngeal arches in which Et-1 in the environment of the postmigratory cranial neural crest specifies the lower jaw and other ventral arch fates.