T
Thomas Nordahl Petersen
Researcher at Technical University of Denmark
Publications - 44
Citations - 14247
Thomas Nordahl Petersen is an academic researcher from Technical University of Denmark. The author has contributed to research in topics: Metagenomics & Resistome. The author has an hindex of 20, co-authored 37 publications receiving 11547 citations. Previous affiliations of Thomas Nordahl Petersen include University of Copenhagen.
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Journal ArticleDOI
SignalP 4.0: discriminating signal peptides from transmembrane regions
Thomas Nordahl Petersen,Søren Brunak,Søren Brunak,Gunnar von Heijne,Gunnar von Heijne,Henrik Nielsen +5 more
TL;DR: SignalP 4.0 was the best signal-peptide predictor for all three organism types but was not in all cases as good as SignalP 3.0 according to cleavage-site sensitivity or signal- peptide correlation when there are no transmembrane proteins present.
Journal ArticleDOI
SignalP 5.0 improves signal peptide predictions using deep neural networks
Jose Juan Almagro Armenteros,Konstantinos D. Tsirigos,Casper Kaae Sønderby,Thomas Nordahl Petersen,Ole Winther,Ole Winther,Søren Brunak,Søren Brunak,Gunnar von Heijne,Gunnar von Heijne,Henrik Nielsen +10 more
TL;DR: A deep neural network-based approach that improves SP prediction across all domains of life and distinguishes between three types of prokaryotic SPs is presented.
Journal ArticleDOI
A generic method for assignment of reliability scores applied to solvent accessibility predictions
Bent O. Petersen,Thomas Nordahl Petersen,Pernille Andersen,Pernille Andersen,Morten Nielsen,Claus Lundegaard +5 more
TL;DR: This work has implemented a method that predicts the relative surface accessibility of an amino acid and simultaneously predicts the reliability for each prediction, in the form of a Z-score, which is comparable to the performance of the currently best public available method, Real-SPINE.
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Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage
Rene S. Hendriksen,Patrick Munk,Patrick Murigu Kamau Njage,Bram A. D. van Bunnik,Luke McNally,Oksana Lukjancenko,Timo Röder,David F. Nieuwenhuijse,Susanne Karlsmose Pedersen,Jette Kjeldgaard,Rolf Sommer Kaas,Philip Thomas Lanken Conradsen Clausen,Josef Korbinian Vogt,Pimlapas Leekitcharoenphon,Milou G.M. van de Schans,T. Zuidema,Ana Maria de Roda Husman,Simon Rasmussen,Bent O. Petersen,Clara Amid,Guy Cochrane,Thomas Sicheritz-Pontén,Heike Schmitt,Jorge Raul Matheu Alvarez,Awa Aidara-Kane,Sünje Johanna Pamp,Ole Lund,Tine Hald,Mark E. J. Woolhouse,Marion Koopmans,Håkan Vigre,Thomas Nordahl Petersen,Frank Møller Aarestrup +32 more
TL;DR: It is suggested that global AMR gene diversity and abundance vary by region, and that improving sanitation and health could potentially limit the global burden of AMR.
Journal ArticleDOI
CPHmodels-3.0—remote homology modeling using structure-guided sequence profiles
TL;DR: CPHmodels-3.0 was benchmarked in the CASP8 competition and produced models for 94% of the targets, 74% were predicted as high reliability models, and the remaining 26% low reliably models could superimpose to the true 3D structure with an average RMSD of 9.3 Å.