Thomas W. Hoffmann

TL;DR: In this article, a relationship between the host and the gut microbiota govern intestinal homeostasis is revealed, and the authors reveal that host genes affect the composition and function of the Gut microbiota, altering the production of microbial metabolites and intestinal inflammation.

TL;DR: This study confirms the alteration of the bacterial microbiota and is the first demonstration of the existence of an altered fungal microbiota in Crohn's disease patients, suggesting that fungi may play a role in pathogenesis.

TL;DR: This study confirms the alteration of the mucosa-associated bacterial microbiota in IBD and SC, and is the first evidence of the existence of an alteredacterial microbiota in CAC clearly different from the one in SC patients.

TL;DR: Analysis of host–microbiota interactions in mice that were mono-associated with six microorganisms that are representative of inflammatory bowel disease (IBD)-associated dysbiosis reveals that microorganisms with a potential role in intestinal homeostasis and inflammation have specific impacts on the host, and suggests several tracks to follow to understand intestinal homestasis and IBD pathogenesis better.

TL;DR: Understanding of the fungal microbiota composition and its impact on IBD has greatly increased in the past 8 years and special attention was paid to the various effects of this microbial community on the IBD, i.e., the mechanisms and immune pathways involved in these interactions.