Anne Bourrier

TL;DR: In this article, a relationship between the host and the gut microbiota govern intestinal homeostasis is revealed, and the authors reveal that host genes affect the composition and function of the Gut microbiota, altering the production of microbial metabolites and intestinal inflammation.

TL;DR: It is observed that fungal microbiota is skewed in IBD, with an increased Basidiomycota/Ascomycota ratio, a decreased proportion of Saccharomyces cerevisiae and an increased proportion of Candida albicans compared with HS, indicating that a Crohn's disease-specific gut environment may favour fungi at the expense of bacteria.

TL;DR: Based on results from a clinical trial, administration of azathioprine within 6 months of diagnosis of CD was no more effective than conventional management in increasing time of clinical remission.

TL;DR: A successful response to adalimumab was observed in about two-thirds of CD patients with SSBS and was prolonged in nearly half of them till the end of follow-up, and more than half of the patients were free of surgery 4 years after treatment initiation.

TL;DR: Higher colonization by donor microbiota was associated with maintenance of remission and no safety signal was identified in this pilot study in adults with colonic or ileo-colonic CD.