F
Fatiha Merabtene
Researcher at University of Paris
Publications - 20
Citations - 1330
Fatiha Merabtene is an academic researcher from University of Paris. The author has contributed to research in topics: Epidermal growth factor receptor & Microsatellite instability. The author has an hindex of 10, co-authored 18 publications receiving 929 citations. Previous affiliations of Fatiha Merabtene include French Institute of Health and Medical Research & Pierre-and-Marie-Curie University.
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Journal ArticleDOI
CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands
Bruno Lamas,Mathias L. Richard,Valentin Leducq,Hang-Phuong Pham,Marie-Laure Michel,Grégory Da Costa,Chantal Bridonneau,Sarah Jegou,Thomas W. Hoffmann,Jane M. Natividad,Loic Brot,Soraya Taleb,Soraya Taleb,Aurélie Couturier-Maillard,Isabelle Nion-Larmurier,Fatiha Merabtene,Philippe Seksik,Anne Bourrier,Jacques Cosnes,Bernhard Ryffel,Bernhard Ryffel,Laurent Beaugerie,Jean-Marie Launay,Philippe Langella,Ramnik J. Xavier,Harry Sokol +25 more
TL;DR: In this article, a relationship between the host and the gut microbiota govern intestinal homeostasis is revealed, and the authors reveal that host genes affect the composition and function of the Gut microbiota, altering the production of microbial metabolites and intestinal inflammation.
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EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition.
Audrey Clapéron,Martine Mergey,Thanh Huong Nguyen Ho-Bouldoires,Danijela Matic Vignjevic,Dominique Wendum,Yves Chrétien,Fatiha Merabtene,Alexandra Frazao,Valérie Paradis,Chantal Housset,Nathalie Guedj,Laura Fouassier +11 more
TL;DR: The EGF/EGFR axis triggers EMT in C CA cells highlighting the key role of this pathway in CCA progression.
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Hepatic myofibroblasts promote the progression of human cholangiocarcinoma through activation of epidermal growth factor receptor
Audrey Clapéron,Martine Mergey,Lynda Aoudjehane,Thanh Huong Nguyen Ho-Bouldoires,Dominique Wendum,Aurélie Prignon,Fatiha Merabtene,Delphine Firrincieli,Christèle Desbois-Mouthon,Olivier Scatton,Filomena Conti,Chantal Housset,Laura Fouassier +12 more
TL;DR: A reciprocal cross‐talk between CCA cells and myofibroblasts through the HB‐EGF/EGFR axis contributes to CCA progression.
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The IGF2/IR/IGF1R Pathway in Tumor Cells and Myofibroblasts Mediates Resistance to EGFR Inhibition in Cholangiocarcinoma
Javier Vaquero,Javier Vaquero,Cindy Lobe,Sylvana Tahraoui,Audrey Clapéron,Martine Mergey,Fatiha Merabtene,Dominique Wendum,Cédric Coulouarn,Chantal Housset,Christèle Desbois-Mouthon,Françoise Praz,Laura Fouassier +12 more
TL;DR: To escape EGFR-TKI treatment, CCA tumor cells develop an adaptive mechanism by undergoing an IR/IGF1R-dependent phenotypic switch, involving a contribution of stromal cells.
Journal ArticleDOI
Low Levels of Microsatellite Instability at Simple Repeated Sequences Commonly Occur in Human Hepatocellular Carcinoma
Claire Goumard,Christèle Desbois-Mouthon,Dominique Wendum,Claire Calmel,Fatiha Merabtene,Olivier Scatton,Françoise Praz +6 more
TL;DR: Based on a large series of HCC with various etiologies, this study allowed us to definitely conclude that MSI is not a hallmark of H CC.