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Isabelle Nion-Larmurier
Researcher at University of Paris
Publications - 56
Citations - 5323
Isabelle Nion-Larmurier is an academic researcher from University of Paris. The author has contributed to research in topics: Inflammatory bowel disease & Crohn's disease. The author has an hindex of 22, co-authored 51 publications receiving 4209 citations. Previous affiliations of Isabelle Nion-Larmurier include Pierre-and-Marie-Curie University.
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Low counts of Faecalibacterium prausnitzii in colitis microbiota.
Harry Sokol,Philippe Seksik,Jean-Pierre Furet,Olivier Firmesse,Isabelle Nion-Larmurier,Laurent Beaugerie,Jacques Cosnes,Gérard Corthier,P Marteau,Joël Doré +9 more
TL;DR: The fecal microbiota of patients with IBD differs from that of healthy subjects, and the phylum Firmicutes and particularly the species F. prausnitzii, are underrepresented in A‐IBD patients as well as in IC patients, which could be crucial to gut homeostasis.
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CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands
Bruno Lamas,Mathias L. Richard,Valentin Leducq,Hang-Phuong Pham,Marie-Laure Michel,Grégory Da Costa,Chantal Bridonneau,Sarah Jegou,Thomas W. Hoffmann,Jane M. Natividad,Loic Brot,Soraya Taleb,Soraya Taleb,Aurélie Couturier-Maillard,Isabelle Nion-Larmurier,Fatiha Merabtene,Philippe Seksik,Anne Bourrier,Jacques Cosnes,Bernhard Ryffel,Bernhard Ryffel,Laurent Beaugerie,Jean-Marie Launay,Philippe Langella,Ramnik J. Xavier,Harry Sokol +25 more
TL;DR: In this article, a relationship between the host and the gut microbiota govern intestinal homeostasis is revealed, and the authors reveal that host genes affect the composition and function of the Gut microbiota, altering the production of microbial metabolites and intestinal inflammation.
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Fungal microbiota dysbiosis in IBD
Harry Sokol,Valentin Leducq,Hugues Aschard,Hang-Phuong Pham,Sarah Jegou,Cécilia Landman,David Cohen,David Cohen,Giuseppina Liguori,Anne Bourrier,Isabelle Nion-Larmurier,Jacques Cosnes,Philippe Seksik,Philippe Langella,David Skurnik,Mathias L. Richard,Laurent Beaugerie +16 more
TL;DR: It is observed that fungal microbiota is skewed in IBD, with an increased Basidiomycota/Ascomycota ratio, a decreased proportion of Saccharomyces cerevisiae and an increased proportion of Candida albicans compared with HS, indicating that a Crohn's disease-specific gut environment may favour fungi at the expense of bacteria.
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Impact of the increasing use of immunosuppressants in Crohn’s disease on the need for intestinal surgery
Jacques Cosnes,Isabelle Nion-Larmurier,Laurent Beaugerie,P. Afchain,Emmanuel Tiret,Jean-Pierre Gendre +5 more
TL;DR: Although immunosuppressants have been used more frequently over the last 25 years, there was no significant decrease of the need for surgery, or of intestinal complications of Crohn’s disease.
Journal ArticleDOI
Fecal microbiota transplantation to maintain remission in Crohn’s disease: a pilot randomized controlled study
Harry Sokol,Cécilia Landman,Philippe Seksik,Laurence Berard,Melissa Montil,Isabelle Nion-Larmurier,Anne Bourrier,Guillaume Le Gall,Valérie Lalande,Alexis de Rougemont,Julien Kirchgesner,Anne Daguenel,Marine Cachanado,Alexandra Rousseau,Elodie Drouet,Michelle Rosenzwajg,Hervé Hagege,Xavier Dray,David Klatzman,Philippe Marteau,Laurent Beaugerie,Tabassome Simon +21 more
TL;DR: Higher colonization by donor microbiota was associated with maintenance of remission and no safety signal was identified in this pilot study in adults with colonic or ileo-colonic CD.