T
Tim Kümmerle
Researcher at University of Cologne
Publications - 27
Citations - 2702
Tim Kümmerle is an academic researcher from University of Cologne. The author has contributed to research in topics: Darunavir & Men who have sex with men. The author has an hindex of 11, co-authored 24 publications receiving 1990 citations. Previous affiliations of Tim Kümmerle include Praxis.
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Journal ArticleDOI
Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive Partner Is Using Suppressive Antiretroviral Therapy
Alison Rodger,Valentina Cambiano,Tina Bruun,Pietro Vernazza,Simon Collins,Jan van Lunzen,Giulio Maria Corbelli,Vicente Estrada,Anna Maria Geretti,Apostolos Beloukas,David Asboe,Pompeyo Viciana,Félix Gutiérrez,Bonaventura Clotet,Christian Pradier,Jan Gerstoft,Rainer Weber,Katarina Westling,Gilles Wandeler,Jan M. Prins,Armin Rieger,Marcel Stoeckle,Tim Kümmerle,Teresa Bini,Adriana Ammassari,Richard Gilson,Ivanka Krznaric,Matti Ristola,Robert Zangerle,Pia Handberg,Antonio Antela,Sris Allan,Andrew N. Phillips,Jens D Lundgren +33 more
TL;DR: Evaluating the rate of within-couple HIV transmission among serodifferent heterosexual and MSM couples during periods of sex without condoms and when the HIV-positive partner had HIV-1 RNA load less than 200 copies/mL found no phylogenetically linked transmissions.
Journal ArticleDOI
Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study
Alison Rodger,Valentina Cambiano,Tina Bruun,Pietro Vernazza,Simon Collins,Olaf Degen,Giulio Maria Corbelli,Vicente Estrada,Anna Maria Geretti,Apostolos Beloukas,Apostolos Beloukas,Dorthe Raben,Pep Coll,Andrea Antinori,Nneka Nwokolo,Armin Rieger,Jan M Prins,Anders Blaxhult,Rainer Weber,Arne Van Eeden,Norbert H. Brockmeyer,Amanda Clarke,Jorge del Romero Guerrero,François Raffi,Johannes R. Bogner,Gilles Wandeler,Jan Gerstoft,Félix Gutiérrez,Kees Brinkman,Maria Kitchen,Lars Østergaard,Agathe León,Matti Ristola,Heiko Jessen,Hans-Jürgen Stellbrink,Andrew N. Phillips,Jens D Lundgren,Patricia Cobarsi,Aroa Nieto,Michael Meulbroek,Antonia Carrillo,Jorge Saz,Jorge D.R. Guerrero,Mar Vera García,Mar Masiá,Catalina Robledano,Lorna Leal,Eva G. Redondo,Vicente Estrada,Rocio Marquez,Raquel Sandoval,Pompeyo Viciana,Nuria Espinosa,Luis F. López-Cortés,Daniel Podzamczer,Juan Tiraboschi,Sandra Morenilla,Antonio Antela,Elena Losada,Janey Sewell,Sarah Kirk,Alyson Knott,Thomas Fernandez,Mark Gompels,Louise Jennings,Lana Ward,Julie Fox,Julianne Lwanga,Ming Lee,Richard Gilson,Clifford Leen,Sheila Morris,Dan Clutterbuck,Michael Brady,David Asboe,Serge Fedele,Sarah Fidler,Norbert Brockmeyer,Anja Potthoff,Adriane Skaletz-Rorowski,Johannes Bogner,Ulrich Seybold,Julia Roider,Arne Jessen,Slobodan Ruzicic,Tim Kümmerle,Clara Lehmann,Sindy Bartel,Anja Hüfner,Jürgen K. Rockstroh,Karina Mohrmann,Christoph Boesecke,Ivanka Krznaric,Patrick Ingiliz,Christina Grube,Dominique Braun,Huldrych F. Günthard,Hansjakob Furrer,Andri Rauch,Patrick Schmid,Manuela Rasi,Denise Borso,Markus Stratmann,Oliver Caviezel,Marcel Stoeckle,Manuel Battegay,Philip E. Tarr,Vanessa Christinet,Florent Jouinot,Camille Isambert,Enos Bernasconi,Beatrice Bernasconi,Lene P. Jensen,Anne A. Bayer,Yordanos Yehdego,Ann Bach,Pia Handberg,Gitte Kronborg,Svend s. Pedersen,Nete Bülow,Bente Ramskover,Outi Debnam,Jussi Sutinen,Ronnie Ask,Bernt Hildingsson-Lundh,Katarina Westling,Eeva-Maija Frisen,Gráinne Cortney,Siobhan O'Dea,Stéphane De Wit,Coca Necsoi,Linos Vandekerckhove,Jean-Christophe Goffard,Sophie Henrard,Jan M. Prins,Hans-Henrik Nobel,Annouschka Weijsenfeld,Loek Elsenburg,Danielle Vos,Imke Hoijenga,Elisabeth Gisolf,Petra Van Bentum,Dominique Verhagen,Eric Billaud,Michel Ohayon,Daniel Gosset,Alexandre Fior,Gilles Pialoux,Pelagie Thibaut,Julie Chas,Vincent Leclercq,Vincent Pechenot,Vincent Coquelin,Christian Pradier,Sophie Breaud,Veronique Touzeau-Romer,Maria Kitchen Maria Geit,Mario Sarcletti,Martin Gisinger,Angela Oellinger,Samanta Menichetti,Teresa Bini,Cristina Mussini,Marianna Meschiari,Antonio Di Biagio,Lucia Taramasso,Benedetto Maurizio Celesia,M. Gussio,Nuno Janeiro +168 more
TL;DR: The results suggest that the risk of HIV transmission in gay couples through condomless sex when HIV viral load is suppressed is effectively zero, which supports the message of the U=U (undetectable equals untransmittable) campaign, and the benefits of early testing and treatment for HIV.
Journal ArticleDOI
Antibody 10-1074 suppresses viremia in HIV-1-infected individuals
Marina Caskey,Till Schoofs,Henning Gruell,Allison Settler,Theodora K. Karagounis,Edward F. Kreider,Ben Murrell,Nico Pfeifer,Lilian Nogueira,Thiago Y. Oliveira,Gerald H. Learn,Yehuda Z. Cohen,Clara Lehmann,Daniel Gillor,Irina Shimeliovich,Cecilia Unson-O’Brien,Daniela Weiland,Alexander. Robles,Tim Kümmerle,Christoph Wyen,Rebeka Levin,Maggi Witmer-Pack,Kemal Eren,Caroline Ignacio,Szilard Kiss,Anthony P. West,Hugo Mouquet,Barry S. Zingman,Barry S. Zingman,Roy M. Gulick,Tibor Keler,Pamela J. Bjorkman,Michael S. Seaman,Beatrice H. Hahn,Gerd Fätkenheuer,Sarah J. Schlesinger,Michel C. Nussenzweig,Michel C. Nussenzweig,Florian Klein +38 more
TL;DR: The results demonstrate the safety and activity of 10-1074 in humans and support the idea that antibodies targeting the V3 glycan supersite might be useful for the treatment and prevention of HIV-1 infection.
Journal ArticleDOI
Combination therapy with anti-HIV-1 antibodies maintains viral suppression
Pilar Mendoza,Henning Gruell,Lilian Nogueira,Joy A. Pai,Allison L. Butler,Katrina G. Millard,Clara Lehmann,Isabelle Suárez,Thiago Y. Oliveira,Julio C. C. Lorenzi,Yehuda Z. Cohen,Christoph Wyen,Christoph Wyen,Tim Kümmerle,Tim Kümmerle,Theodora K. Karagounis,Ching-Lan Lu,Lisa Handl,Cecilia Unson-O’Brien,Roshni Patel,Carola Ruping,Maike Schlotz,Maggi Witmer-Pack,Irina Shimeliovich,Gisela Kremer,Eleonore Thomas,Kelly E. Seaton,Jill Horowitz,Anthony P. West,Pamela J. Bjorkman,Georgia D. Tomaras,Roy M. Gulick,Nico Pfeifer,Gerd Fätkenheuer,Michael S. Seaman,Florian Klein,Marina Caskey,Michel C. Nussenzweig,Michel C. Nussenzweig +38 more
TL;DR: It is concluded that the combination of the anti-HIV-1 monoclonal antibodies 3BNC117 and 10-1074 can maintain long-term suppression in the absence of antiretroviral therapy in individuals with antibody-sensitive viral reservoirs.
Journal ArticleDOI
Pegylated interferon-alpha for the treatment of sexually transmitted acute hepatitis C in HIV-infected individuals.
Martin Vogel,Jacob Nattermann,Axel Baumgarten,Gerd Klausen,Bernhard Bieniek,Knud Schewe,Heiko Jessen,Christoph Boesecke,Michael Rausch,Thomas A. Lutz,Stefan Fenske,Dietmar Schranzo,Tim Kümmerle,Christoph Schuler,A. Theisen,Christoph Mayr,Thomas Seidel,Jürgen K. Rockstroh +17 more
TL;DR: Treatment of hepatitis C in HIV-positive individuals in the acute phase of infection leads to high rates of sustained virological response, and Peg-IFN alone showed similar treatment response rates and lower incidence of anaemia compared with peg-IFn+ribavirin combination therapy.