T
Toshitaka Fujisawa
Researcher at National Institute of Genetics
Publications - 70
Citations - 4331
Toshitaka Fujisawa is an academic researcher from National Institute of Genetics. The author has contributed to research in topics: Lernaean Hydra & Cell signaling. The author has an hindex of 32, co-authored 69 publications receiving 4065 citations. Previous affiliations of Toshitaka Fujisawa include Graduate University for Advanced Studies & Heidelberg University.
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Journal ArticleDOI
The dynamic genome of Hydra
Jarrod Chapman,Ewen F. Kirkness,Oleg Simakov,Oleg Simakov,Steven E. Hampson,Therese Mitros,Thomas Weinmaier,Thomas Rattei,Prakash G. Balasubramanian,Jon Borman,Dana A. Busam,Kathryn Disbennett,Cynthia Pfannkoch,Nadezhda Sumin,Granger G. Sutton,Lakshmi D. Viswanathan,Brian P. Walenz,David Goodstein,Uffe Hellsten,Takeshi Kawashima,Simon E. Prochnik,Nicholas H. Putnam,Nicholas H. Putnam,Nicholas H. Putnam,Shengquiang Shu,Bruce Blumberg,Catherine E. Dana,Lydia Gee,Dennis F. Kibler,Lee Law,Dirk Lindgens,Daniel E. Martínez,Jisong Peng,Philip A. Wigge,Philip A. Wigge,Bianca Bertulat,Corina Guder,Yukio Nakamura,Suat Özbek,Hiroshi Watanabe,Konstantin Khalturin,Georg Hemmrich,Andre Franke,René Augustin,Sebastian Fraune,Eisuke Hayakawa,Shiho Hayakawa,Mamiko Hirose,Jung Shan Hwang,Kazuho Ikeo,Chiemi Nishimiya-Fujisawa,Atshushi Ogura,Atshushi Ogura,Toshio Takahashi,Patrick R. H. Steinmetz,Xiaoming Zhang,Roland Aufschnaiter,Marie Kristin Eder,Anne Kathrin Gorny,Anne Kathrin Gorny,Willi Salvenmoser,Alysha M. Heimberg,Benjamin M. Wheeler,Kevin J. Peterson,Angelika Böttger,Patrick Tischler,Alexander Wolf,Takashi Gojobori,Karin A. Remington,Karin A. Remington,Robert L. Strausberg,J. Craig Venter,Ulrich Technau,Bert Hobmayer,Thomas C. G. Bosch,Thomas W. Holstein,Toshitaka Fujisawa,Hans R. Bode,Charles N. David,Daniel S. Rokhsar,Daniel S. Rokhsar,Robert Steele +81 more
TL;DR: Comparisons of the Hydra genome to the genomes of other animals shed light on the evolution of epithelia, contractile tissues, developmentally regulated transcription factors, the Spemann–Mangold organizer, pluripotency genes and the neuromuscular junction.
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Analysis of a piwi-Related Gene Implicates Small RNAs in Genome Rearrangement in Tetrahymena
TL;DR: The authors found that small RNAs function to specify sequences to be eliminated by a mechanism similar to RNA-mediated gene silencing in Tetrahymena thermophila, and they were not observed in TWI1 knockout cells and required PDD1, another gene required for rearrangement, for expression.
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Universal occurrence of the vasa-related genes among metazoans and their germline expression in Hydra.
TL;DR: The results suggest that the vas-related genes occur universally among metazoans and that their expression in germline cells was established at least before cnidarian evolution.
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Systematic isolation of peptide signal molecules regulating development in hydra: LWamide and PW families
Toshio Takahashi,Yojiro Muneoka,Jan U. Lohmann,Maria S. Lopez de Haro,Gaby Solleder,Thomas C. G. Bosch,Charles N. David,Hans R. Bode,Osamu Koizumi,Hiroshi Shimizu,Masayuki Hatta,Toshitaka Fujisawa,Tsutomu Sugiyama +12 more
TL;DR: The evidence obtained so far suggests that hydra contains a large number of peptide signal molecules involved in regulating developmental or other processes in cnidaria, which can be isolated and their functions examined systematically with the new approach developed in this study.
Journal ArticleDOI
Expression and evolutionary conservation of nanos- related genes in Hydra
Kazufumi Mochizuki,Hiroko Sano,Satoru Kobayashi,Chiemi Nishimiya-Fujisawa,Toshitaka Fujisawa +4 more
TL;DR: The function of nanos-related genes in the germline appears to be well conserved from primitive to highly evolved metazoans.