T
Tucker A. Patterson
Researcher at National Center for Toxicological Research
Publications - Â 87
Citations - Â 6662
Tucker A. Patterson is an academic researcher from National Center for Toxicological Research. The author has contributed to research in topics: Neurotoxicity & Anesthetic. The author has an hindex of 28, co-authored 80 publications receiving 6176 citations. Previous affiliations of Tucker A. Patterson include Food and Drug Administration & Elsevier.
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Journal ArticleDOI
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
Leming Shi,Laura H. Reid,Wendell D. Jones,Richard Shippy,Janet A. Warrington,Shawn C. Baker,Patrick J. Collins,Francoise de Longueville,Ernest S. Kawasaki,Kathleen Y. Lee,Yuling Luo,Yongming Andrew Sun,James C. Willey,Robert Setterquist,Gavin M. Fischer,Weida Tong,Yvonne P. Dragan,David J. Dix,Felix W. Frueh,Federico Goodsaid,Damir Herman,Roderick V. Jensen,Charles D. Johnson,Edward K. Lobenhofer,Raj K. Puri,Uwe Scherf,Jean Thierry-Mieg,Charles Wang,Michael A Wilson,Paul K. Wolber,Lu Zhang,William Slikker,Shashi Amur,Wenjun Bao,Catalin Barbacioru,Anne Bergstrom Lucas,Vincent Bertholet,Cecilie Boysen,Bud Bromley,Donna Brown,Alan Brunner,Roger D. Canales,Xiaoxi Megan Cao,Thomas A. Cebula,James J. Chen,Jing Cheng,Tzu Ming Chu,Eugene Chudin,John F. Corson,J. Christopher Corton,Lisa J. Croner,Christopher Davies,Timothy Davison,Glenda C. Delenstarr,Xutao Deng,David Dorris,Aron Charles Eklund,Xiaohui Fan,Hong Fang,Stephanie Fulmer-Smentek,James C. Fuscoe,Kathryn Gallagher,Weigong Ge,Lei Guo,Xu Guo,Janet Hager,Paul K. Haje,Jing Han,Tao Han,Heather Harbottle,Stephen C. Harris,Eli Hatchwell,Craig A. Hauser,Susan D. Hester,Huixiao Hong,Patrick Hurban,Scott A. Jackson,Hanlee P. Ji,Charles R. Knight,Winston Patrick Kuo,J. Eugene LeClerc,Shawn Levy,Quan Zhen Li,Chunmei Liu,Ying Liu,Michael Lombardi,Yunqing Ma,Scott R. Magnuson,Botoul Maqsodi,Timothy K. McDaniel,Nan Mei,Ola Myklebost,Baitang Ning,Natalia Novoradovskaya,Michael S. Orr,Terry Osborn,Adam Papallo,Tucker A. Patterson,Roger Perkins,Elizabeth Herness Peters,Ron L. Peterson,Kenneth L. Philips,P. Scott Pine,Lajos Pusztai,Feng Qian,Hongzu Ren,Mitch Rosen,Barry A. Rosenzweig,Raymond R. Samaha,Mark Schena,Gary P. Schroth,Svetlana Shchegrova,Dave D. Smith,Frank Staedtler,Zhenqiang Su,Hongmei Sun,Zoltan Szallasi,Zivana Tezak,Danielle Thierry-Mieg,Karol L. Thompson,Irina Tikhonova,Yaron Turpaz,Beena Vallanat,Christophe Van,Stephen J. Walker,Sue Jane Wang,Yonghong Wang,Russell D. Wolfinger,Alexander Wong,Jie Wu,Chunlin Xiao,Qian Xie,Jun Xu,Wen Yang,Liang Zhang,Sheng Zhong,Yaping Zong +136 more
TL;DR: This study describes the experimental design and probe mapping efforts behind the MicroArray Quality Control project and shows intraplatform consistency across test sites as well as a high level of interplatform concordance in terms of genes identified as differentially expressed.
Journal ArticleDOI
Ketamine-induced neuronal cell death in the perinatal rhesus monkey.
William Slikker,Xiaoju Zou,Charlotte E. Hotchkiss,Rebecca L. Divine,Natalya Sadovova,Nathan C. Twaddle,Daniel R. Doerge,Andrew C. Scallet,Tucker A. Patterson,Joseph P. Hanig,Merle G. Paule,Cheng Wang +11 more
TL;DR: Ketamine increased N-methyl-D-aspartate (NMDA) receptor NR1 subunit messenger RNA in the frontal cortex where enhanced cell death was apparent and a shorter duration of ketamine anesthesia did not result in neuronal cell death in the 5-day-old monkey.
Journal ArticleDOI
Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys
Merle G. Paule,Mi Li,Richard R. Allen,Fang Liu,X. Zou,Charlotte E. Hotchkiss,Joseph P. Hanig,Tucker A. Patterson,William Slikker,Cheng Wang +9 more
TL;DR: It is demonstrated that a single 24-h episode of ketamine anesthesia, occurring during a sensitive period of brain development, results in very long-lasting deficits in brain function in primates and provides proof-of-concept that general anesthesia during critical periods of brainDevelopment can result in subsequent functional deficits.
Journal ArticleDOI
Performance comparison of one-color and two-color platforms within the Microarray Quality Control (MAQC) project
Tucker A. Patterson,Edward K. Lobenhofer,Stephanie Fulmer-Smentek,Patrick J. Collins,Tzu-Ming Chu,Wenjun Bao,Hong Fang,Ernest S. Kawasaki,Janet Hager,Irina Tikhonova,Stephen J. Walker,Liang Zhang,Patrick Hurban,Francoise de Longueville,James C. Fuscoe,Weida Tong,Leming Shi,Russell D. Wolfinger +17 more
TL;DR: Cumulatively, these comparisons indicate that data quality is essentially equivalent between the one- and two-color approaches and strongly suggest that this variable need not be a primary factor in decisions regarding experimental microarray design.
Journal ArticleDOI
Expression of genes related to oxidative stress in the mouse brain after exposure to silver-25 nanoparticles.
M.F. Rahman,J. Wang,Tucker A. Patterson,U.T. Saini,Bonnie L. Robinson,Glenn D. Newport,Richard C. Murdock,John J. Schlager,Saber M. Hussain,Syed F. Ali +9 more
TL;DR: The data suggest that Ag-25 nanoparticles may produce neurotoxicity by generating free radical-induced oxidative stress and by altering gene expression, producing apoptosis and neurotoxicity.