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Baitang Ning

Researcher at Food and Drug Administration

Publications -  34
Citations -  3985

Baitang Ning is an academic researcher from Food and Drug Administration. The author has contributed to research in topics: microRNA & Biology. The author has an hindex of 16, co-authored 29 publications receiving 3641 citations. Previous affiliations of Baitang Ning include National Center for Toxicological Research & United States Department of Health and Human Services.

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The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

Leming Shi, +136 more
- 01 Sep 2006 - 
TL;DR: This study describes the experimental design and probe mapping efforts behind the MicroArray Quality Control project and shows intraplatform consistency across test sites as well as a high level of interplatform concordance in terms of genes identified as differentially expressed.
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The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

Leming Shi, +201 more
- 01 Aug 2010 - 
TL;DR: P predictive models for classifying a sample with respect to one of 13 endpoints indicative of lung or liver toxicity in rodents, or of breast cancer, multiple myeloma or neuroblastoma in humans are generated.
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Comparison of RNA-seq and microarray-based models for clinical endpoint prediction.

Wenqian Zhang, +81 more
- 25 Jun 2015 - 
TL;DR: It is demonstrated thatRNA-seq outperforms microarrays in determining the transcriptomic characteristics of cancer, while RNA-seq and microarray-based models perform similarly in clinical endpoint prediction.
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Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

TL;DR: The basal gene expression profiles of 251 drug-metabolizing enzymes in untreated primary human hepatocytes from six donors, four commonly used hepatoma cell lines, and one transfected human liver epithelial cell line are characterized, providing references for researchers to choose carefully appropriate in vitro models for studies of drug metabolism and toxicity.
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Comparing next-generation sequencing and microarray technologies in a toxicological study of the effects of aristolochic acid on rat kidneys.

TL;DR: It is found that RNA-Seq was more sensitive in detecting genes with low expression levels, while similar gene expression patterns were observed for both platforms, which helped to maintain a consistent biological interpretation with time-tested microarray platforms.