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Damir Herman

Researcher at University of Arkansas for Medical Sciences

Publications -  18
Citations -  4594

Damir Herman is an academic researcher from University of Arkansas for Medical Sciences. The author has contributed to research in topics: Gene expression profiling & Cancer. The author has an hindex of 12, co-authored 18 publications receiving 4389 citations. Previous affiliations of Damir Herman include National Institutes of Health.

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The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

Leming Shi, +136 more
- 01 Sep 2006 - 
TL;DR: This study describes the experimental design and probe mapping efforts behind the MicroArray Quality Control project and shows intraplatform consistency across test sites as well as a high level of interplatform concordance in terms of genes identified as differentially expressed.
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The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

Leming Shi, +201 more
- 01 Aug 2010 - 
TL;DR: P predictive models for classifying a sample with respect to one of 13 endpoints indicative of lung or liver toxicity in rodents, or of breast cancer, multiple myeloma or neuroblastoma in humans are generated.
Journal ArticleDOI

The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

TL;DR: The results provide practical guidance to choose the appropriate FC and P-value cutoffs when selecting a given number of DEGs and recommend the use of FC-ranking plus a non-stringent P cutoff as a straightforward and baseline practice in order to generate more reproducible DEG lists.
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Rat toxicogenomic study reveals analytical consistency across microarray platforms

TL;DR: The real-world toxicogenomic data set reported here showed high concordance in intersite and cross-platform comparisons and gene lists generated by fold-change ranking were more reproducible than those obtained by t-test P value or Significance Analysis of Microarrays.