V. S. Nadarajan

TL;DR: The results offer an explanation for the heterogeneity of TKI responses across individuals and suggest the possibility of personalizing therapy with BH3 mimetics to overcome BIM-polymorphism–associated TKI resistance.

TL;DR: The allele frequencies of HPA in Malays and Chinese were found to be similar those of other East and South-East Asian populations, while those of Indians were comparable to the frequencies found in Europeans.

TL;DR: A 60-year-old man who initially presented with phenotype of polycythemia vera, which evolved into chronic myeloid leukemia and back to PV once treatment with imatinib was commenced, implies that two independent clones exist with the JAK2 V617F clone only achieving clonal dominance when BCR-ABL positive clones are suppressed by imatinIB.

TL;DR: It is concluded that a high prevalence of iron deficiency is present among regular male blood donors and all female donors and the use of the copper sulphate screening test as a sole criterion for anaemia screening should be reviewed.

TL;DR: The parameter RBC‐Y can be useful as a screening measure for iron deficiency in blood donors, and compare favourably with haemoglobin which only showed a sensitivity of 50%, although specificity was 91% at a cut‐off value of 125 g L−1.