V
Vikrant Kumar
Researcher at National University of Singapore
Publications - 30
Citations - 2036
Vikrant Kumar is an academic researcher from National University of Singapore. The author has contributed to research in topics: Population & Haplogroup. The author has an hindex of 15, co-authored 28 publications receiving 1762 citations. Previous affiliations of Vikrant Kumar include Genome Institute of Singapore & Indian Statistical Institute.
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Journal ArticleDOI
Mapping human genetic diversity in Asia
Mahmood Ameen Abdulla,Ikhlak Ahmed,Anunchai Assawamakin,Anunchai Assawamakin,Jong Bhak,Samir K. Brahmachari,Gayvelline C. Calacal,Amit Kumar Chaurasia,Chien-Hsiun Chen,Jieming Chen,Yuan-Tsong Chen,Jiayou Chu,Eva Maria Cutiongco-de la Paz,Maria Corazon A. De Ungria,Frederick C. Delfin,Juli Edo,Suthat Fuchareon,Ho Ghang,Takashi Gojobori,Junsong Han,Sheng Feng Ho,Boon Peng Hoh,Wei Huang,Hidetoshi Inoko,Pankaj Jha,Timothy A. Jinam,Li Jin,Jongsun Jung,Daoroong Kangwanpong,Jatupol Kampuansai,Giulia C. Kennedy,Preeti Khurana,Hyung Lae Kim,Kwangjoong Kim,Sangsoo Kim,Woo Yeon Kim,Kuchan Kimm,Ryosuke Kimura,Tomohiro Koike,Supasak Kulawonganunchai,Vikrant Kumar,Poh San Lai,Jong-Young Lee,Sunghoon Lee,Edison T. Liu,Partha P. Majumder,Kiran Kumar Mandapati,Sangkot Marzuki,Wayne Mitchell,Wayne Mitchell,Mitali Mukerji,Kenji Naritomi,Chumpol Ngamphiw,Norio Niikawa,Nao Nishida,Bermseok Oh,Sangho Oh,Jun Ohashi,Akira Oka,Rick Twee-Hee Ong,Carmencita Padilla,Prasit Palittapongarnpim,Henry B. Perdigon,Maude E. Phipps,Maude E. Phipps,Eileen Png,Yoshiyuki Sakaki,Jazelyn M. Salvador,Yuliana Sandraling,Vinod Scaria,Mark Seielstad,Mohd Ros Sidek,Amit Sinha,Metawee Srikummool,Herawati Sudoyo,Sumio Sugano,Helena Suryadi,Yoshiyuki Suzuki,Kristina A. Tabbada,Adrian Tan,Katsushi Tokunaga,Sissades Tongsima,Lilian P. Villamor,Eric Wang,Ying Wang,Haifeng Wang,Jer-Yuarn Wu,Huasheng Xiao,Shuhua Xu,Jin Ok Yang,Yin Yao Shugart,Hyang Sook Yoo,Wentao Yuan,Guoping Zhao,Bin Alwi Zilfalil +94 more
TL;DR: The results suggest that there may have been a single major migration of people into Asia and a subsequent south-to-north migration across the continent, and that genetic ancestry is strongly correlated with linguistic affiliations as well as geography.
Journal ArticleDOI
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer.
King Pan Ng,Axel M. Hillmer,Charles Chuah,Charles Chuah,Wen Chun Juan,Tun Kiat Ko,Audrey S.M. Teo,Pramila N. Ariyaratne,Naoto Takahashi,Kenichi Sawada,Yao Fei,Yao Fei,Sheila Soh,Wah Heng Lee,John W.J. Huang,John Carson Allen,Xing Yi Woo,Niranjan Nagarajan,Vikrant Kumar,Anbupalam Thalamuthu,Wan Ting Poh,Ai Leen Ang,Hae Tha Mya,Gee Fung How,L.Y. Yang,Liang Piu Koh,Balram Chowbay,Chia-Tien Chang,V. S. Nadarajan,Wee Joo Chng,Hein Than,Lay Cheng Lim,Yeow Tee Goh,Shenli Zhang,Dianne Poh,Patrick Tan,Patrick Tan,Ju Ee Seet,Mei-Kim Ang,Noan-Minh Chau,Quan Sing Ng,Daniel Shao-Weng Tan,Manabu Soda,Kazutoshi Isobe,Markus M. Nöthen,Tien Yin Wong,Atif Shahab,Xiaoan Ruan,Valere Cacheux-Rataboul,Wing-Kin Sung,Eng Huat Tan,Yasushi Yatabe,Hiroyuki Mano,Hiroyuki Mano,Ross A. Soo,Tan Min Chin,Wan-Teck Lim,Yijun Ruan,Yijun Ruan,S. Tiong Ong +59 more
TL;DR: The results offer an explanation for the heterogeneity of TKI responses across individuals and suggest the possibility of personalizing therapy with BH3 mimetics to overcome BIM-polymorphism–associated TKI resistance.
Journal ArticleDOI
Y-chromosome evidence suggests a common paternal heritage of Austro-Asiatic populations
Vikrant Kumar,Arimanda N. S. Reddy,Jagedeesh P. Babu,Tipirisetti Nageswar Rao,Banrida T. Langstieh,Banrida T. Langstieh,Kumarasamy Thangaraj,Alla G. Reddy,Lalji Singh,Battini Mohan Reddy +9 more
TL;DR: The findings are consistent with the linguistic evidence, which suggests that the linguistic ancestors of the Austro-Asiatic populations have originated in India and then migrated to Southeast Asia.
Journal ArticleDOI
GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-Cell Lymphoma
Karin E. Smedby,Jia Nee Foo,Christine F. Skibola,Hatef Darabi,Lucia Conde,Henrik Hjalgrim,Vikrant Kumar,Ellen T. Chang,Ellen T. Chang,Nathaniel Rothman,James R. Cerhan,Angela Brooks-Wilson,Angela Brooks-Wilson,Emil Rehnberg,Ishak D. Irwan,Lars P. Ryder,Peter de Nully Brown,Paige M. Bracci,Luz Agana,Jacques Riby,Wendy Cozen,Scott Davis,Scott Davis,Patricia Hartge,Lindsay M. Morton,Richard K. Severson,Sophia S. Wang,Sophia S. Wang,Susan L. Slager,Zachary S. Fredericksen,Anne J. Novak,Neil E. Kay,Thomas M. Habermann,Bruce K. Armstrong,Anne Kricker,Sam Milliken,Mark P. Purdue,Claire M. Vajdic,Peter Boyle,Qing Lan,Shelia Hoar Zahm,Yawei Zhang,Tongzhang Zheng,Stephen Leach,John J. Spinelli,Martyn T. Smith,Stephen J. Chanock,Leonid Padyukov,Lars Alfredsson,Lars Klareskog,Bengt Glimelius,Bengt Glimelius,Mads Melbye,Edison T. Liu,Hans-Olov Adami,Hans-Olov Adami,Keith Humphreys,Jianjun Liu +57 more
TL;DR: The results reveal the presence of allelic heterogeneity within the HLA class II region influencing FL susceptibility and indicate a possible shared genetic etiology with diffuse large B-cell lymphoma.
Journal ArticleDOI
Single-cell atlas of lineage states, tumor microenvironment and subtype-specific expression programs in gastric cancer.
Vikrant Kumar,Kalpana Ramnarayanan,Raghav Sundar,Nisha Padmanbahan,Supriya Srivastava,Mayu Koiwa,Tadahito Yasuda,Vivien Koh,Kie Kyon Huang,Su Ting Tay,Shamaine Wei Ting Ho,Angie Lay Keng Tan,Takatsugu Ishimoto,Guowei Kim,Asim Shabbir,Qingfeng Chen,Zhang Biyan,Shengli Xu,Kong-Peng Lam,Huey Yew Jeffrey Lum,Ming Teh,Wei Peng Yong,Jimmy Bok Yan So,Patrick Tan +23 more
TL;DR: In this article, a comprehensive single-cell atlas of Gastric cancer (GC) heterogeneity was generated, comprising 48 samples from 31 patients across clinical stages and histological subtypes, including 34 distinct cell-lineage states including novel rare cell populations.