V
Vadim A. Soloshonok
Researcher at University of the Basque Country
Publications - 417
Citations - 16252
Vadim A. Soloshonok is an academic researcher from University of the Basque Country. The author has contributed to research in topics: Enantioselective synthesis & Amino acid. The author has an hindex of 64, co-authored 406 publications receiving 14170 citations. Previous affiliations of Vadim A. Soloshonok include University of Oklahoma & Centre national de la recherche scientifique.
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Journal ArticleDOI
Efficient Large-Scale Synthesis of Picolinic Acid-Derived Nickel(II) Complexes of Glycine
TL;DR: An efficient large-scale method for the preparation of 2-[N-(α-picolyl)amino]acetophenone (PAAP) and 2-[n-amino]-benzophenone(PABP) with NiII complexes with glycine is described in this paper.
MonographDOI
Current fluoroorganic chemistry : new synthetic directions, technologies, materials, and biological applications
TL;DR: In this paper, 30 top-notch chapter-reviews on recent methodological developments in the area of synthetic fluoro-organic chemistry, Fluoric technology, and biological applications of fluorinated compounds are presented.
Journal ArticleDOI
Detrifluoroacetylative in Situ Generation of Free 3-Fluoroindolin-2-one-Derived Tertiary Enolates: Design, Synthesis, and Assessment of Reactivity toward Asymmetric Mannich Reactions
TL;DR: The discovery of detrifluoroacetylative in situ generation of a new type of fluorinated amide enolates derived from 3-fluoroindolin-2-one and their asymmetric Mannich additions with sulfinylaldimines bearing fluoroalkyl groups is reported.
Journal ArticleDOI
Fluorine-containing pharmaceuticals approved by the FDA in 2020: Synthesis and biological activity
Yingjie Yu,Aiyao Liu,Gagan Dhawan,Haibo Mei,Wei Zhang,Kunisuke Izawa,Vadim A. Soloshonok,Vadim A. Soloshonok,Jianlin Han +8 more
TL;DR: Thirteen new fluorine-containing drugs, which have been granted approval by the US Food and Drug Administration in 2020, are profiled in this review, providing a spectrum of biological activity, medicinal chemistry discovery, and synthetic approaches.
Journal ArticleDOI
New generation of nucleophilic glycine equivalents
TL;DR: In this article, a new generation of nucleophilic glycine equivalents, designed to contain a functional framework, that allows control over the physical properties as well as the reactivity, is described.