V
Vadim A. Soloshonok
Researcher at University of the Basque Country
Publications - 417
Citations - 16252
Vadim A. Soloshonok is an academic researcher from University of the Basque Country. The author has contributed to research in topics: Enantioselective synthesis & Amino acid. The author has an hindex of 64, co-authored 406 publications receiving 14170 citations. Previous affiliations of Vadim A. Soloshonok include University of Oklahoma & Centre national de la recherche scientifique.
Papers
More filters
Journal ArticleDOI
Asymmetric synthesis of (3S,1'S)-3-(1-amino-2,2,2-trifluoroethyl)-1-(alkyl)-indolin-2-one derivatives by addition of (S)-N-t-butylsulfinyl-3,3,3-trifluoroacetaldimine to 1-(alkyl)-indolin-2-ones.
Ping Qian,Chen Xie,Lingmin Wu,Haibo Mei,Vadim A. Soloshonok,Vadim A. Soloshonok,Jianlin Han,Yi Pan +7 more
TL;DR: This paper presents the first study of the addition reactions between amide-derived nucleophiles and chiral CF3-containing N-sulfinyl-imines and shows them to be of general practical application for preparation of various oxindole derivatives in a diastereomerically pure form.
Journal ArticleDOI
Concise asymmetric synthesis of configurationally stable 4-trifluoromethyl thalidomide.
TL;DR: A reliable asymmetric approach is developed for preparation of hitherto unknown 4-trifluoromethyl-substituted thalidomide in (3S,4R) and (3R,4S) enantiomerically pure forms that may serve as useful lead compounds for the development of a new generation of thalidmide-based pharmaceuticals.
Journal ArticleDOI
Practical Methods for the Synthesis of Symmetrically α,α-Disubstituted α-Amino Acids
Journal ArticleDOI
Design and Synthesis of a New Generation of ‘NH’-Ni(II) Complexes of Glycine Schiff Bases and their Unprecedented C-H vs. N-H Chemoselectivity in Alkyl Halide Alkylations and Michael Addition Reactions
TL;DR: In this paper, the synthesis of Ni(II) complexes that contain a secondary rather than a tertiary amino group, as well as the unusual chemoselectivity, was demonstrated in alkyl halide alkylations and Michael addition reactions.
Journal ArticleDOI
Self-Disproportionation of Enantiomers (SDE) via achiral gravity-driven column chromatography of N-fluoroacyl-1-phenylethylamines
Alicja Wzorek,Alicja Wzorek,Angelika Kamizela,Azusa Sato,Vadim A. Soloshonok,Vadim A. Soloshonok +5 more
TL;DR: In this paper, the self-disproportionation of enantiomers via gravity-driven achiral column chromatography of a series of N -fluoroacetylated amides derived from 1-phenylethylamine is described.